Cytosolic Calcium
Intracellular acidification associated with changes in free cytosolic calcium Evidence for Ca2+/H+ exchange via a plasma membrane Ca(2+) ATPase in vascular smooth muscle cells
... The purpose of this study was to define the mechanism whereby agonists that increase free cytosolic calcium (Cai2+) affect intracellular pH (pHi) in smooth muscle. Rat aortic vascular smooth muscle cells ...
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Hepatitis B Virus Replication Is Associated with an HBx-Dependent Mitochondrion-Regulated Increase in Cytosolic Calcium Levels
... basal cytosolic calcium levels are maintained at around 100 nM (10); however, hepatocytes have higher cyto- solic basal calcium levels, and our calculated basal level of 250 to 275 nM in cells ...
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Sources of variability in cytosolic calcium transients triggered by stimulation of homogeneous uro-epithelial cell monolayers
... in calcium transients observed in urothelial cells in response to application of an external agonist and to scratch ...in cytosolic calcium concentration over ...individual calcium transients ...
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Regulation of parathyroid hormone release and cytosolic calcium by extracellular calcium in dispersed and cultured bovine and pathological human parathyroid cells
... extracellular calcium, cytosolic calcium, and PTH secretion in adult, neonatal, and cultured bovine as well as pathological human parathyroid ...extracellular calcium, P less than 0.01), and a ...
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The Hepatitis B Virus X Protein Elevates Cytosolic Calcium Signals by Modulating Mitochondrial Calcium Uptake
... was calcium dependent and stimulated HBV replication (33, ...intracellular calcium signaling are incompletely under- ...extracellular calcium into HepG2 cells ...IP3-regulated cytosolic ...
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1,25 Dihydroxyvitamin D increases hepatocyte cytosolic calcium levels A potential regulator of vitamin D 25 hydroxylase
... in cytosolic calcium have been shown to regulate cellular ...on cytosolic calcium levels in ...increases cytosolic calcium levels by 24% at ...
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Role of cytosolic calcium independent plasmalogen selective phospholipase A2 in hypoxic injury to rabbit proximal tubules
... of calcium-independent PLA2 activity is associated with a cytoprotective ...in cytosolic calcium-independent PLA2, which was selective for plasmalogen substrates (control 444 +/- 69 vs hypoxia 1,675 ...
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Porcine Circovirus Type 2 Induces ORF3-Independent Mitochondrial Apoptosis via PERK Activation and Elevation of Cytosolic Calcium
... induce cytosolic ROS accumulation and loss of ...in cytosolic ROS levels after treatment with 10 M DCFH-DA for 30 min at 37°C in the ...in cytosolic ROS levels were evaluated according to the mean ...
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Nicotinic receptors on rat alveolar macrophages dampen ATP-induced increase in cytosolic calcium concentration
... In view of the natural occurrence of nAChR ligands in the alveolar compartment (e.g. choline) and of the clini- cal relevance of nicotine contained within cigarette smoke, the potential presence of a cholinergic ...
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Synaptic vesicle exocytosis and increased cytosolic calcium are both necessary but not sufficient for activity dependent bulk endocytosis
... Activity-dependent dephosphorylation of dynamin I cor- relates with the triggering of ADBE (Clayton et al. 2009). Furthermore, over-expression of dominant negative dynamin I phospho-mutants, delivery of competitive ...
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Direct preconditioning of cultured chick ventricular myocytes Novel functions of cardiac adenosine A2a and A3 receptors
... the cytosolic calcium level is not known in the present study, the data support the notion that increased cal- cium entry during the initial brief hypoxia is the mechanism down-modulating the responsiveness ...
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Vasopressin V1 receptors on the principal cells of the rabbit cortical collecting tubule Stimulation of cytosolic free calcium and inositol phosphate production via coupling to a pertussis toxin substrate
... The aim of the present study was to determine a if rabbit cortical collecting tubule RCCT cells possess a VI receptor coupled to the mobilization of cytosolic calcium [Ca+]f, in addition[r] ...
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Systems Modeling of Calcium Homeostasis and Mobilization in Platelets Mediated by Ip3 and Store-Operated Calcium Entry
... mediated calcium regulation was extended to include mechanisms for calcium influx from the extracellular ...their cytosolic calcium responses to a transient stimulatory ...platelet ...
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Isolation of a human myocardial cytosolic phospholipase A2 isoform Fast atom bombardment mass spectroscopic and reverse phase high pressure liquid chromatography identification of choline and ethanolamine glycerophospholipid substrates
... minor cytosolic calcium-independent phospholipase A2 isoform that hydrolyzes plasmenylcholine and phosphatidylcholine substrates at similar rates and possesses a pH optimum of ...major cytosolic ...
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On the mechanism of impaired insulin secretion in chronic renal failure
... It has been suggested that a sustained rise in resting levels of cytosolic calcium [Ca2+]i of pancreatic islets is responsible for impaired insulin secretion in chronic renal failure (CRF). Evidence for ...
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Transient elevations of cytosolic free calcium retard subsequent apoptosis in neutrophils in vitro
... Elevation of cytosolic calcium ([Ca2+]i) has been reported to induce apoptosis in a number of cell types. However, in the neutrophil, which undergoes apoptosis constitutively during aging in vitro, ...
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Role of cholesterol and sphingolipids in brain development and neurological diseases
... of cytosolic calcium level occurs in the astrocytes in case of AD which leads to the neur- onal ...the cytosolic calcium that causes neuronal cell death [51, ...
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Calcium signaling in neurodegeneration
... both cytosolic calcium concentrations [142] and ERK1/2 activation ...a calcium-selective cat- ion current at the plasma membrane ...in calcium signaling: Relevance for APP ...
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Impaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na/Ca exchanger 3
... Membrane preparation and immunoblot analysis. A super- natant containing membrane proteins of skeletal muscle homogenates was analyzed by SDS/PAGE. Detection by ECL Plus detection reagents (Amersham) was performed as ...
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Stimulation by leukotriene D4 of increases in the cytosolic concentration of calcium in dimethylsulfoxide differentiated HL 60 cells
... extracellular calcium and diminished by lanthanum, but not affected by nifedipine nor associated with changes in membrane potential, as measured with the fluorescent probe ...
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