cytotoxic drugs
Level of Adherence to Cytotoxic Drugs by Breast Cancer Patients’ in Lagos State University Teaching Hospital
... Level of Adherence to Cytotoxic Drugs by Breast Cancer Patients’ in Lagos State University Teaching Hospital Popoola Abiodun1*, Samira Makanjuola2, Sowunmi Anthonia3, Igwilo Adaeze1, Mob[r] ...
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Knowledge and Attitude about Exposure to Cytotoxic Drugs in Oncology Nurses
... 16. Ensslin AS, Pethran A, Schierl R, Fruhmann G. Urinary platinum in hospital personnel occupationally exposed to platinum- containing antineoplastic drugs. International archives of occupational and ...
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MARINE NATURAL PRODUCTS - AS A SOURCE OF CYTOTOXIC DRUGS
... selling drugs are ...summarizes cytotoxic marine compounds from various marine plants like Cephalotaxus fortunei, Scilla sibirica, Aconitum hemsleyanum var leueanthus, Murraya koenigii, Marine sponge ...
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The effect of cytotoxic drugs on the DNA metabolism and proliferation of lymphoblasts
... AraC is a known inhibitor of DNA synthesis and it is generally considered that this is its major mode of action as a cytotoxic agent. The actual cause of cytotoxicity as a result of the inhibition of DNA synthesis ...
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Chemotherapy Induced Amenorrhea in Women Treated with Chemotherapy for Breast Carcinoma in Yalgado Ouédraogo Teaching Hospital in Ouagadougou, Burkina Faso
... Breast cancer is the leading cancer in women worldwide. Almost a third (32.7%) of pa- tients affected by this disease are under 50 years [1], so probably no menopausal. Che- motherapy which is one of the main therapeutic ...
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Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
... Antifibrotic strategies discussed in this Review series Various antiinflammatory/immunosuppressive/cytotoxic drugs including colchicine, azathioprine, cyclophosphamide, prednisone, thali[r] ...
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Effects of cytotoxic immunosuppressants on tuberculin sensitive lymphocytes in guinea pigs
... showed broader immunosuppressive effects including significant toxicities for intermitotic lymphocytes. This drug depleted pools of T cells and markedly impaired the in vitro proliferative responses of residual ...
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Antibody Drug Conjugates: A Leap Ahead in Cancer Treatment
... of the immune system. Moreover, proteins that are over expressed on carcinoma cells, including the human epidermal growth factor receptor 2 (HER2); prostate- specific membrane antigen (PSMA) and cryptic family protein 1 ...
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Combinatorial effects of doxorubicin and retargeted tissue factor by intratumoral entrapment of doxorubicin and proapoptotic increase of tumor vascular infarction
... both drugs using different ...of cytotoxic drugs such as doxorubicin with tTF-NGR-induced tumor vessel infarction can improve pharmacodynamics of the drugs by new mechanisms, entrapping a ...
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Efficacy of adjuvant chemotherapy for non-small cell lung cancer assessed by metastatic potential associated with ACTN4
... for cytotoxic drugs, the metastatic potential of A549 lung adenocarcinoma cells was significantly reduced by ACTN4 shRNA in in vitro assays and in an animal transplantation ...
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A lovastatin-elicited genetic program inhibits M2 macrophage polarization and enhances T cell infiltration into spontaneous mouse mammary tumors
... other cytotoxic drugs [23-25], however, which prompted a number of ongoing phase I/II clinical trials to test whether statins improve chemotherapeutic effectiveness of other anti-cancer drugs in skin ...
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A Commentary: Herbal Medicine Offers Great Potential in Support of Metronomic Cancer Therapy
... Background: In spite of the advances in Cancer treatment, limitations exist. Re- fractory cases and late presentations are particularly worrying. The uncertainty of cure and the high costs have led to the popularly of ...
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Knowledge guided gene prioritization reveals new insights into the mechanisms of chemoresistance
... We also found direct literature evidence for eight genes among the top 15 genes for doxorubicin (Table 2; Additional file 4). As an example, CSNK2A1 (Casein kin- ase 2 alpha 1) and its paralog CSNK2A2 are serine/ ...
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Promising cytotoxic activity profile of fermented wheat germ extract (Avemar®) in human cancer cell lines
... Fermented wheat germ extract (FWGE) is currently used as nutrition supplement for cancer patients. Limited recent data suggest antiproliferative, antimetastatic and immunological effects which were at least in part ...
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Solid Tumor Therapy Using a Cannon and Pawn Combination Strategy
... anti-tumor drugs hold great promise for reducing side effects and improving tumor-site drug retention in the treatment of solid ...and cytotoxic drugs for solid tumor ...
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Determinants of health-related quality of life in patients with small cell lung cancer: a systematic PubMed review and meta-analysis
... Abstract: Objective ― Symptoms of small cell lung cancer (SCLC), along with the side-effects of treatment interventions (e.g. nausea and vomiting due to cytotoxic drugs), are supposed to influence ...
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Influence of cell cycle phase specific agents on simian fetal hemoglobin synthesis
... In that report and elsewhere, we 2 and others 3 suggested that the increase in fetal hemoglobin induced by hydroxyurea and other cell cycle-dependent, phase-specific cytotoxic drugs migh[r] ...
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The use of pyridazine thione derivative in the preparation of some new heterocyclic compounds with expected antitumor activity
... 1, it has been shown that 5,7,13,17a and 17b are the compounds of lowest IC50 which means that they are the most effective cytotoxic drugs, accordingly compounds 13,17a and 17b can be us[r] ...
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Potential anticancer properties of bioactive compounds of <em>Gymnema sylvestre</em> and its biofunctionalized silver nanoparticles
... vitro cytotoxic activity of the biofunctionalized green-synthesized SNPs (GSNPs) indicated that the sensitivity of HT29 human colon adenocarcinoma cells for cytotoxic drugs is higher than that of ...
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The Role of Pharmacoethnicity in the Development of Cytotoxic and Molecular Targeted Drugs in Oncology
... conducted. Both studies compared etoposide/cisplatin vs. irinotecan/cisplatin. The dose and administration schedules of the drugs were exactly the same. The patient demo- graphics showed that 86% and 57% of the ...
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