Cytotoxic T lymphocytes
Functional Constraints of Influenza A Virus Epitopes Limit Escape from Cytotoxic T Lymphocytes
... Cytotoxic T lymphocytes (CTL) play an important role in the control of viral infections (10). To evade these CTL responses, viruses can exploit a variety of mechanisms to prevent recog- nition by ...
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Partial Escape of HIV-1 from Cytotoxic T Lymphocytes during Chronic Infection
... ⫹ cytotoxic T lymphocytes (CTLs) exert a major selective pressure that shapes viral sequences (22) through evolution to avoid CTL antiviral activity (3, ...
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Dynamics of acute hepatitis C virus subject to responses of cytotoxic T lymphocytes and antibodies
... and T- ...infection, cytotoxic T lymphocytes develop to kill host infected ...and cytotoxic T lymphocytes to study the dynamics of AHCVI by mathematical ...
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Protection from Ebola Virus Mediated by Cytotoxic T Lymphocytes Specific for the Viral Nucleoprotein
... Cytotoxic T lymphocytes (CTLs) are proposed to be critical for protection from intracellular pathogens such as Ebola virus. However, there have been no demonstrations that protection against Ebola ...
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Role of B cells and cytotoxic T lymphocytes in clearance of and immunity to rotavirus infection in mice.
... and T cells in the resolution of primary infection and protection against rotavirus ...immune cytotoxic T lymphocytes (CTLs) has been shown both to protect against acute rotavirus- induced ...
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Elicitation of Simian Immunodeficiency Virus-Specific Cytotoxic T Lymphocytes in Mucosal Compartments of Rhesus Monkeys by Systemic Vaccination
... sampling T lymphocytes from those anatomic compart- ...mucosal cytotoxic T lymphocytes (CTL) specific for simian immunodeficiency virus (SIV) and simian HIV can be reproducibly sampled ...
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Dengue virus protein recognition by virus-specific murine CD8+ cytotoxic T lymphocytes.
... We studied the recognition by murine dengue virus-specific major histocompatibility complex class I-restricted, CD8+ cytotoxic T lymphocytes CTL of dengue virus proteins using recombinan[r] ...
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Interleukin-10 Increases Th1 Cytokine Production and Cytotoxic Potential in Human Papillomavirus-Specific CD8+ Cytotoxic T Lymphocytes
... the cytotoxic activity of HPV-specific CTL against autol- ogous tumor targets could be increased by the combination of IL-2 with other cytokines previously reported to be able to act as cytotoxic ...
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Vaccinia virus-specific CD8+ cytotoxic T lymphocytes in humans.
... After infection with vaccinia virus, the 10% infected, gamma-irradiated autologous PBMC and the 90% uninfected, gamma-irradiated autologous feeder PBMC were combined and resuspended to 1[r] ...
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Cytotoxic T lymphocytes form an antigen independent ring junction
... Activated T cells hunting for antigenic MHCp com- plexes are attracted to peripheral tissues by chemoat- tractants and endothelial ...helper T cell ISs can be fully reconstituted and visu- alized in real ...
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Differences in activities of murine retroviral long terminal repeats in cytotoxic T lymphocytes and T-lymphoma cells.
... In contrast to T-lymphoma cells, in which the LTRs of T-lymphomagenic virus SL3-3 and Moloney murine leukemia virus are more active than those of other viruses, transcriptional activity [r] ...
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Normal self proteins as targets for tumour specific cytotoxic T lymphocytes (CTL)
... as T cells generated by in vitro restimulation with splenic adherent cells infected with adenovirus mdm2 followed by restimulation with DCs infected with VV mdm2 ("Protocol 1", Figure ...stable T ...
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Recognition of cloned influenza virus hemagglutinin gene products by cytotoxic T lymphocytes.
... Despite the fact that HAs derived fromn different influenza A virus subtypes are serologically non-cross-reactive, the HA has been implicated by previous experiments to be a target antig[r] ...
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Dengue virus-specific cross-reactive CD8+ human cytotoxic T lymphocytes.
... Recombinant viruses were propagated in Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest Stimulation with live dengue virus of peripheral blood mononuclear cells from a d[r] ...
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Specific cytotoxic T lymphocytes are involved in in vivo clearance of infectious bronchitis virus.
... Cytotoxic T-lymphocyte (CTL) responses to infectious bronchitis virus (IBV) were determined at regular intervals between 3 and 30 days postinfection ...2 T cells, as the CTL response could be ...
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Recognition of adenovirus E1A gene products on immortalized cell surfaces by cytotoxic T lymphocytes.
... The fact that susceptibility of target cells to lysis by CTL can be associated with the expression of early encoded prior to viral DNA replication viral gene products on cell membranes a[r] ...
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Recognition of a B cell leukemia associated minor histocompatibility antigen by cytotoxic T lymphocytes.
... Abbreviations used in this paper: mHag, minor histocompatibility antigen; BMT, bone marrow transplantation; CVHD, graft-vs-host disease; GVL, grafl-vs- leukemia; B-ALL, B-[r] ...
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Control of mucosal virus infection by influenza nucleoprotein-specific CD8+ cytotoxic T lymphocytes
... vaccinated mice. Balb/c mice were immunized intramuscu- larly with 200 μg of influenza A/PR/8/34 (H1N1) NP DNA vaccine, 2–3 weeks apart, three times, and then challenged with 1LD 50 of influenza A/HK/68 (H3N2) virus. ...
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Targeting miR 23a in CD8+ cytotoxic T lymphocytes prevents tumor dependent immunosuppression
... the T/APC interface: TCR signaling strength, coreceptor signals, and NOTCH ...Jurkat T cells were cotransfected with reporter constructs containing full-length 3′-UTRs of the indicated genes, together with ...
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Phenotypic and functional consequences of herpesvirus saimiri infection of human CD8+ cytotoxic T lymphocytes.
... Infection of CD8+ CTL with HVS led to the outgrowth of a population of cells that were maintained in medium containing IL-2 10 U/ml with viability of 85 to 95%, whereas CD8+ CTL not infe[r] ...
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