Cytotoxic T lymphocytes (CTLs)
Dynamic changes of cytotoxic T lymphocytes (CTLs), natural killer (NK) cells, and natural killer T (NKT) cells in patients with acute hepatitis B infection
... blood cytotoxic T lymphocytes (CD3 + CD8 + ) in AHB patients in the early stage of infection were higher than in the healthy control group and among CHB ...+ lymphocytes might reflect ...
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Human Papillomavirus Type 16 (HPV-16) Virus-Like Particle L1-Specific CD8+ Cytotoxic T Lymphocytes (CTLs) Are Equally Effective as E7-Specific CD8+ CTLs in Killing Autologous HPV-16-Positive Tumor Cells in Cervical Cancer Patients: Implications for L1 Dendritic Cell-Based Therapeutic Vaccines
... ⴙ T lymphocytes responses in cervical cancer patients, L1 VLP-loaded dendritic cells (DCs) were used to stimulate peripheral blood lymphocytes from cervical cancer patients and such responses were ...
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Increased frequency of antigen specific CD8+ cytotoxic T lymphocytes infiltrating an Epstein Barr virus–associated gastric carcinoma
... of cytotoxic T cell epitopes within Epstein-Barr virus (EBV) onco- gene latent membrane protein 1 (LMP1): evidence for HLA A2 super- type-restricted immune recognition of EBV-infected cells by LMP1-specific ...
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Cytotoxic T lymphocytes form an antigen independent ring junction
... helper T cells, in which initial MHCp complex accumulation occurs in the periphery of the contact area before a ring junction ...helper T cells, which predisposes CTL to rapid ring junction formation in ...
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Vaccinia virus-specific CD8+ cytotoxic T lymphocytes in humans.
... After infection with vaccinia virus, the 10% infected, gamma-irradiated autologous PBMC and the 90% uninfected, gamma-irradiated autologous feeder PBMC were combined and resuspended to 1[r] ...
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Engineering Nanoparticles for Targeted Remodeling of the Tumor Microenvironment to Improve Cancer Immunotherapy
... antigen-4; CTLs: cytotoxic T lymphocytes; DCs: dendritic cells; ECM: extracellular matrix; EGFR: epidermal growth factor receptor; EPR: enhanced permeability and retention; ERBB2IP: erbb2 ...
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Validation of analytical methods in compliance with good manufacturing practice: a practical approach
... and Cytotoxic T Lymphocytes (CTLs), both cell therapy products that we will produce, in GMP conditions, for clinical trials of immunotherapy and regenerative medicine, and dendritic cells ...
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Effector differentiation is not prerequisite for generation of memory cytotoxic T lymphocytes
... cytokine treatment. Our results also indicate that mem- ory cells can arise independently of the strength of TCR stimulus or the number of cell divisions. The fact that effector cells that were generated with high-dose ...
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Molecular Imaging in Tracking Tumor-Specific Cytotoxic T Lymphocytes (CTLs)
... Although T cell therapy has made impressive progress on cancer treatment from bench to bedside these years, the process to gain regulatory approval is still slow partly due to lack of knowledge of biodis- ...
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DNA vaccination for prostate cancer: key concepts and considerations
... cancer; CTLs: Cytotoxic T lymphocytes; DNA: Deoxyribonucleic acid; DOM: Domain of fragment C tetanus toxin; DTH: Delayed-type hypersensitivity; EP: Electroporation; FDA: US food and drug ...
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Simian immunodeficiency virus-specific CD8+ lymphocyte response in acutely infected rhesus monkeys.
... 1707 Downloaded from http://jvi.asm.org/ on November 9, 2019 by guest To assess the possible role of cytotoxic T lymphocytes CTLs in containing the spread of human immunodeficiency virus[r] ...
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Immunomodulatory effects of Rhipicephalus haemaphysaloides serpin RHS2 on host immune responses
... 2; CTLs: cytotoxic T lymphocytes; BMDC: bone marrow-derived dendritic cells; DCs: dendritic cells; OVA: ovalbumin; TBD: tick-borne diseases; IL-2: interleukin 2; IL-4: interleukin 4; IFN-γ: ...
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<p>Resistance Mechanism of PD-1/PD-L1 Blockade in the Cancer-Immunity Cycle</p>
... receptor; CTLs, Cytotoxic T lymphocytes; CTLA-4, Cytotoxic T-lymphocyte-associated antigen-4; DCs, Dendritic cells; DDR, DNA damage repair; EGFR, Epidermal growth factor ...
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Overlapping cytotoxic T-lymphocyte and B-cell antigenic sites on the influenza virus H5 hemagglutinin.
... 6246 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest To define the recognition site of cytotoxic T lymphocytes CTLs on influenza virus H5 hemagglutinin HA, an H5 HA-spe[r] ...
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Tim-3 expression and its role in hepatocellular carcinoma
... CTLA-4: Cytotoxic T lymphocyte-associated protein 4; CTLs: CD8+ cytotoxic T lymphocytes; DC: Dendritic cell; EMT: Epithelial-mesenchymal transition; EpCAM: Epithelial cell ...
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Memory and distribution of virus-specific cytotoxic T lymphocytes (CTLs) and CTL precursors after rotavirus infection.
... 65, 1991 tinal and nonintestinal lymphocytes after rotavirus infection, adult mice were inoculated orally or via the hind footpad with RRV; virus-specific cytotoxic activities in intesti[r] ...
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HLA dependent tumour development: a role for tumour associate macrophages?
... and cytotoxic T lymphocytes function while HLA-G induces the secretion of pro-angiogenic cytokines and chemokine thanks to an activator KIR receptor expressed by a minority of peripheral NK ...
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MUC1 Antigen Specific CD8 T Lymphocytes Targeting MCF7 and MDA MB 231 Human Breast Adenocarcinoma Cell Lines
... patients. Cytotoxic T lymphocytes gener- ated from naïve CD8 T cells seem to have potent cytotoxic activity and can be used in adoptive immunotherapy [3] ...to T cells, have ...
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A phase II trial of stereotactic body radiotherapy with concurrent anti PD1 treatment in metastatic melanoma: evaluation of clinical and immunologic response
... events; CTLs: cytotoxic T cells; CTLA-4: cytotoxic T lymphocyte- associated antigen 4; ELISA: enzyme-linked immunosorbent assay; EORTC: European Organization of Research and Treatment ...
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Prognostic significance of PD-L1 expression and CD8+ T cell infiltration in pulmonary neuroendocrine tumors
... CD8+ T cells, as an adaptive immune-resistance mechanism that suppresses local effector T-cell function ...CD8+ T cell infiltration manifests as a result of the body’s efforts at immune protection ...
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