Cytotoxicity and Apoptosis
Cytotoxicity and apoptosis induced by nanobacteria in human breast cancer cells
... assay. Apoptosis was examined by transmission electron microscopy and flow ...of apoptosis, such as chromatin condensation, nuclear fragmentation, nuclear dissolution, mitochondrial swelling, and the ...
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Cytotoxicity and Apoptosis Produced by Cytochrome P450 2E1 in Hep G2 Cells
... with apoptosis, such as membrane blebbing, cyto- plasmic shrinkage, as well as massive destruction into apo- ptotic bodies, were observed after treatment of E47 cells with ...developing apoptosis and in the ...
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Phycocyanin from Spirulina platensis Induces Cytotoxicity and Apoptosis in T47D Cells
... conditions of T47D cells after being treated with phy- cocyanin at the concentration of 1650 μg/mL (IC 50 ) and 3300 μg/mL (2IC 50 ). Living cells are stained green and dead cells are stained as orange under fluorescence ...
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In vitro cytotoxicity and induction of apoptosis by silica nanoparticles in human HepG2 hepatoma cells
... Discussion With their dramatically increasing applications in the indus- trial and biomedical fields, the in vitro and in vivo biodis- tribution and biosafety of silica nanoparticles have attracted more and more ...
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RasGAP-derived peptide GAP159 enhances cisplatin-induced cytotoxicity and apoptosis in HCT116 cells
... from apoptosis in a Ras/PI3K/Akt- dependent manner 5 ...induce apoptosis 4 and markedly reduce Akt ...of apoptosis induced by a variety of genotoxins and other anti-cancer treatments in several tumor ...
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Garcinia dulcis fruit extract induced cytotoxicity and apoptosis in HepG2 liver cancer cell line
... Copyright © 2015 Mohd Fadzelly Abu Bakar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, ...
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The effect of Bacillus coagulans on cytotoxicity and apoptosis induced by Salmonella Typhimurium in HT-29 cell culture
... of apoptosis by acridine orange and ethidium bromide ...of apoptosis, appeared green containing bright dots in nuclei or orange con- taining condensed nuclei, ...
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MK2206 potentiates cisplatin-induced cytotoxicity and apoptosis through an interaction of inactivated Akt signaling pathway
... shown; bars represent S.D. Figure 4 Influence of combined MK2206 treatment on CDDP-induced apoptosis in urothelial cancer cell lines. A.1, cells were exposed with MK2206 (500nM) alone for the indicated times. A.2, ...
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Second-generation proteasome inhibitor carfilzomib enhances doxorubicin-induced cytotoxicity and apoptosis in breast cancer cells
... by activation of JNK-mediated apoptotic pathway and inhibition of NF-κB. DISCUSSION The clinical success of the first-generation PI Bortezomib as an anticancer therapy for multiple myeloma and relapsed mantle cell ...
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Silver-doped graphene oxide nanocomposite triggers cytotoxicity and apoptosis in human hepatic normal and carcinoma cells
... inhibit cytotoxicity, thus suggesting that different mechanisms are responsible for cell toxicity in different ...of apoptosis by rGO–Ag nano- composite in CHANG and HepG2 ...
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The Effect Of Moringa Oleifera Leaf Extract On Cytotoxicity And Apoptosis Pathway In Breast Cancer Cell (Mcf-7)
... induce apoptosis in various cancer cell leading their death mechanism pathways by activation or inhibition of ...induced apoptosis in A459 lung cancer cells by upregulating expression of pro- apoptotic ...
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Combination of 5-fluorouracil and Lipopolysaccharide Synergistically Induces Cytotoxicity and Apoptosis in MCF-7 Human Breast Cancer Cells
... Furthermore, the expression of NF-κB was positively correlated with ERK2 (r=1, p=0.01). DISCUSSION Although 5-FU is a chemotherapeutic agent, which is commonly used for the treatment of different types of solid tumors, ...
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Combination of 5-fluorouracil and Lipopolysaccharide Synergistically Induces Cytotoxicity and Apoptosis in MCF-7 Human Breast Cancer Cells
... Furthermore, the expression of NF-κB was positively correlated with ERK2 (r=1, p=0.01). DISCUSSION Although 5-FU is a chemotherapeutic agent, which is commonly used for the treatment of different types of solid tumors, ...
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Enhancement of Cytotoxicity and Apoptosis Induction of Doxorubicin by Brazilein Containing Fraction of Secang (Caesalpinia sappan L.) on T47D Cells
... the cytotoxicity of Brazilein containing fraction (BCF) in single and its combination with doxorubicin on T47D ...potent cytotoxicity with IC 50 value of 403 nM and 68 μg/mL, ...the cytotoxicity of ...
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Effect of the Ethanolic Extract of Passiflora edulis F Flavicarpa Leaves on Viability, Cytotoxicity and Apoptosis of Colon Cancer Cell Lines
... Flavicarpa, were identified, and their biological activity on cell viability, cytotoxicity and pro-apoptotic potential were determined over SW480 and Caco-2 human cancer cell lines. Compounds with chemopreventive ...
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Trichloromethane fraction of Incarvillea compacta induces lytic cytotoxicity and apoptosis in Epstein Barr virus positive gastric cancer AGS cells
... Since R2 showed different inhibition effects on AGS cells and EBV positive AGS cells, we take further investi- gations on R2. Gastric cancer has been reported to be associated with EBV [31]. EBV persists in EBV positive ...
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In-vitro cytotoxicity and apoptosis mechanism of ethyl acetate extract from Trichoderma reesei strain TV221 associated with marine sponge: Stylissa flabelliformis
... then apoptosis test with double staining acridine orange-ethidium bromide method was performed Ethyl acetate extract fermented from ...spur apoptosis process on colon cancer cells ...
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Isochondodendrine and 2[prime or minute]-norcocsuline: additional alkaloids from Triclisia subcordata induce cytotoxicity and apoptosis in ovarian cancer cell lines
... To evaluate apoptosis caused by isochondodendrine and 2 0 - norcocsuline in OVCAR-8 cells, western blot assay was carried out according to described procedure. 7 Briey, 200 000 OVCAR- 8 cells per ml were seeded ...
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Evaluation of Cytotoxicity and Apoptosis Inducing Effects of N (5 mercapto 1,3,4 thiadiazol 2 yl) 2 phenylacetamide Derivatives as Caspase Enzymes Activators
... caspase 9 activity (%) *** Figure 8: The effects of compounds A-E on the activity of caspase-9 in HT-29 cell line compared to control drug (Doxorubicin) A new series of cytotoxic previously 1,3,4-thiadiazole derivatives ...
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Apoptosis, Cytotoxicity and Cell Proliferation. 4 th edition
... The mitochondrial transmembrane potential can be measured easily using a variety of potentiometric dyes, together with flow cytometry or fluorescence microscopy. In many publications MPT is considered to be an early ...
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