D-gal
Ampelopsin attenuates brain aging of D-gal-induced rats through miR-34a-mediated SIRT1/mTOR signal pathway
... with D-gal-induced brain aging revealed an obvious expression of miR- 34a; in contrast, it could be significantly suppressed upon DHM ...inhibited D-gal-induced apoptosis and rescued impaired ...
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α-D-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal α-galactosidase A in Fabry disease
... and Gal-DNJ 8 in cell culture media, agalsidase beta was incubated with increasing concentrations of these compounds, followed by capture of the enzyme on concanavalin A (ConA) sepharose beads, washing to remove ...
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Original Article rhEPO affects apoptosis in hippocampus of aging rats by upregulating SIRT1
... tem. Bcl-xl knockout embryonic mice do not survive and have a large number of apoptotic cells in the central nervous system. However, although Bax knockout embryonic rat do not survive, their central nervous system do ...
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Metabolomics study of the therapeutic mechanism of <em>Schisandra chinensis</em> lignans on aging rats induced by D-galactose
... from d -gal (9 weeks) samples and close to that of d -gal (3 weeks) samples in both negative and positive ion ...from d -gal (9 weeks) samples and close to that of d ...
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Original Article Erythropoietin suppresses D-galactose-induced aging of rats via the PI3K/Akt/Nrf2-ARE pathway
... Western blot was performed to evaluate the protein expression of Akt, p-Akt, Nrf2, and Cu-Zn SOD in neurons of the hippocampal CA1 region. The results showed that the expression of Akt changed little in each group, while ...
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Acute kidney injury and inflammatory response of sepsis following cecal ligation and puncture in D-galactose-induced aging rats
... in d -gal-induced aging ...H d -gal group was most likely to suffer from severe septic shock and hypothermia, and this group exhibited high mortality, impaired renal function, severity of ...
10
Characterizing Human Norovirus Binding to Fresh Strawberries.
... (2012) demonstrated that the binding of HuNoV VLPs to Romaine lettuce leaves was significantly inhibited by pre-treating CWM with lectins that bind the carbohydrate moieties α-D-Gal, α[r] ...
150
C-phycocyanin protects against low fertility by inhibiting reactive oxygen species in aging mice
... Mammalian ovaries possess antioxidant defenses including the antioxidant tripeptide glutathione (GSH), and ROS-scavenging enzymes such as SOD, GSH-Px, CAT, glutathione S-transferase (GST), and peroxiredoxin (PRDX) [4, ...
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The positive effects of Ginsenoside Rg1 upon the hematopoietic microenvironment in a D Galactose induced aged rat model
... a D-gal induced aged rat model, we performed cell cycle phase distribution and apoptosis analysis of BMSCs through flow ...following D-gal administration, which is in agreement with previous ...
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Polysaccharides from Athyrium multidentatum (Doll ) Ching an Attenuated D Galactose Induced Mouse Aging via SIRT1 p53 p21 Pathway
... Age-associated decline in protective and immune regulatory functions may result in an increased susceptibility to infections [13]. In our studies, AMC polysaccharides exhibited significant immune regulatory activity by ...
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Original Article Anti-Alzheimer’s disease effect of essential oil from aerial parts of Salvia miltiorrhiza Bge
... by D-gal plus AlCl 3 , and then the mice in the experimental group were treated with essential oil from aerial parts of ...by D-gal plus AlCl 3 ...by D-gal and AlCl 3 , and has ...
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Gal Gal pili vaccines prevent pyelonephritis by piliated Escherichia coli in a murine model Single component Gal Gal pili vaccines prevent pyelonephritis by homologous and heterologous piliated E coli strains
... the D-Gal p alpha 1----4 D-Gal p beta 1 (Gal-Gal) ...with Gal-Gal pili and challenged 2 wk later intravesicularly with ...
8
Gal80 Dimerization and the Yeast GAL Gene Switch
... HIS3 gal80-⌬BglII) was used to evaluate the GAL gene switch sented the entire GAL80 ORF. The four regions, together with phenotype conferred by all isolated GAL80 mutations. The the PCR primer sets were as ...
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Original Article Overexpression of the galectin-3 during tumor progression in prostate cancer and its clinical implications
... 14]. Gal-3 is known to serve as a tumor suppressor in tumorigenesis and progression in prostate ...of gal-3 in prostate cancer cells was related with reduced cell prolifera- tion, cell migration and ...
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The search for the gene mutations underlying enterotoxigenic Escherichia coli F4ab/ac susceptibility in pigs: a review
... Together with the findings of Bijlsma et al., Billey et al. proposed three different types of F4 receptors [9,17]. The first kind of receptors “bcd” are receptors for all three F4 variants, F4ab, F4ac and F4ad. A second ...
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Introducing intelligence-led conservation: bridging crime and conservation science
... d By doing so, INTERPOL has highlighted the value of utilising ILP in reducing a diverse set of environment crimes (including the illegal exploitation of big cats, ille- gal fishing, a[r] ...
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Role of Nucleoid Associated Protein HU in the Intercellular and Extracellular Milieu
... Hyperthermophilic Thermotoga maritime HU (TmHU) exhibits DNA protection activity and shows remarkable resistant to DNase I-mediated degradation. It also binds to a ~35 bp stretch of DNA unlike E.coli HU with shorter ...
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A carboxy terminal truncation of human alpha galactosidase A in a heterozygous female with Fabry disease and modification of the enzymatic activity by the carboxy terminal domain Increased, reduced, or absent enzyme activity depending on number of amino acid residues deleted
... allele to that of the mutant allele to be 1:1 in cultured fibro- blasts from the heterozygous female of the family. Lympho- cytes a-Gal A activity was lower than that expected, to be z 30% of the normal control. ...
10
Requirement for integrin-linked kinase in neural crest migration and differentiation and outflow tract morphogenesis
... Wnt1-Cre lineage analysis was performed to examine the migration and colonization of NKO mutant cardiac NCCs into the pharyngeal arches and OFT. Wnt1-Cre; ILK f/+ mice were crossed with ILK f/f mice on a Rosa- LacZ [31] ...
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Immunogenicity of Influenza Virus Vaccine Is Increased by Anti-Gal-Mediated Targeting to Antigen-Presenting Cells
... This study describes a method for increasing the immunogenicity of influenza virus vaccines by exploiting the natural anti-Gal antibody to effectively target vaccines to antigen-presenting cells (APC). This method ...
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