De-escalation of antibiotics
De escalation as part of a global strategy of empiric antibiotherapy management A retrospective study in a medico surgical intensive care unit
... to de-escalate was easy. De-escalation is, however, more problematic when the clinician has a strong suspi- cion of bacterial infection with no positive microbial documentation ...of ...
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Original Article Treatment of severe pediatric pneumonia by antibiotic de-escalation therapy
... antibiotic de-escalation therapy was evaluated in this ...antibiotic de-escalation group and control ...Antibiotic de-escalation group showed significantly higher overall ...
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ANTIBIOTIC DE ESCALATION IN THE INTENSIVE THERAPY UNIT A REVIEW
... The increasing resistance rate among nosocomial pathogens is particularly disconcerting. Powerful antibiotics first became commercially available in the 1940s and have saved untold millions of lives. But after ...
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Safety and feasibility of antibiotic de-escalation in bacteremic pneumonia
... more antibiotics (at least a fluoroquinolone and a broad-spectrum antibiotic or vancomycin and a broad-spectrum antibiotic) in all ...for de-escalation, empiric antibiotic therapy was ...
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Antibiotic De-escalation Therapy in Neurosurgical Patients with Ventilator-Associated Pneumonia in Intensive Care Unit: A Retrospective Observational Study
... lower de-escalation rate in our study was the high proportion of unidentified organisms (culture-negative) from culture and sensitivity ...antibiotic de-escalation in culture-negative patients ...
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Enhanced antimicrobial de escalation for pneumonia in mechanically ventilated patients: a cross over study
... Background: Antibiotics are commonly administered to hospitalized patients with infiltrates for possible bacterial pneumonia, often leading to unnecessary treatment and increasing the risk for resistance ...
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Factors influencing the implementation of antibiotic de escalation and impact of this strategy in critically ill patients
... of antibiotics was usually achieved in the case of spectrum narrowing or when switching from beta-lactam + macro- lide or fluoroquinolone to beta-lactam alone in the case of community-acquired pneumonia, even in ...
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Frequency of empiric antibiotic de escalation in an acute care hospital with an established Antimicrobial Stewardship Program
... antibiotic de-escalation at a single center with an established ASP, and as a result, may not be applic- able to all ...antibiotic de-escalation that may have occurred during the study period ...
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Early Empiric Antibiotic De-escalation in Suspected Early Onset Neonatal Sepsis
... antibiotic de-escalation practice in suspected early onset neonatal sepsis and evaluate its outcome within 7 days of ...empiric antibiotics, namely crystalline penicillin and gentamicin were started ...
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Efficacy and safety of de escalation therapy to ertapenem for treatment of infections caused by extended spectrum β lactamase producing Enterobacteriaceae: an open label randomized controlled trial
... For patients in the intervention group (de-escalation group), the previously prescribed group 2 carbapenem was de-escalated to ertapenem. For patients in the con- trol group, the group 2 carbapenem ...
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Doctors’ preferences in de escalating DMARDs in rheumatoid arthritis: a discrete choice experiment
... that de-escalation of DMARDs is feasible in a large number of patients in LDA or disease remission ...whom de-escalation of DMARD therapy is appropriate ...for de-escalation may ...
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De escalation techniques for managing non psychosis induced aggression in adults (Review)
... 2012). De-escalation is a recommended early intervention for managing aggression in order to prevent escalation to the crisis phase (NICE ...in de-escalation techniques is an important ...
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Historic turning point or just another chapter? The results of a foreign-policy summit. EPC Post-Summit Analysis, 24 March 2014
... The €55 billion foreseen for the Single Resolution Fund is a rather small amount considering that potential losses in the European banking sector might be much bigger, maybe even amounting to hundreds of billion. This ...
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Can Interrogation of Tumour Characteristics Lead us to Safely Omit Adjuvant Radiotherapy in Patients with Early Breast Cancer?
... One of the challenges of these studies is that there is no international consensus regarding the level of local recurrence which would be acceptable to clinicians and patients with de- escalation of ...
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Impact of de escalation therapy on clinical outcomes for intensive care unit acquired pneumonia
... ICU-acquired pneumonia was diagnosed on the basis of new pulmonary infiltrates plus at least two of the fol- lowing criteria: fever ≥ 38°C, blood leukocytes ≥ 10,000/ mm 3 or ≤ 3,000/mm 3 and purulent tracheal secretions ...
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Behavioral emergency in the elderly: a descriptive study of patients referred to an Aggression Response Team in an acute hospital
... with the availability of both geriatric and psychiatry consult-liaison services. There is no locked ward or delirium– dementia unit. The ART can be alerted via the pager system when there is a severely agitated patient ...
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Infliximab dose adjustment can improve the clinical and radiographic outcomes of rheumatoid arthritis patients: REVIVE study results
... the escalation and de-escalation of the infliximab dose were selected based on the individual patient’s DAS28 with the clinical response at week ...gradually de-escalated until the dose ...
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Early use of imipenem/cilastatin and vancomycin followed by de escalation versus conventional antimicrobials without de escalation for patients with hospital acquired pneumonia in a medical ICU: a randomized clinical trial
... “ de-escalation ” dif- fered among studies, in that most defined DE with regard to Gram-negative ...with DE defined as a switch to or dis- continuation of a drug class with a less-broad ...
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"De-escalation" strategy using micafungin for the treatment of systemic <em>Candida</em> infections: budget impact in France and Germany
... Background: The incidence of azole-resistant Candida infections is increasing. Consequently, guidelines for treating systemic Candida infection (SCI) recommend a “de-escalation” strat- egy: initial ...
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Escalation and de escalation of international crises : the case of the accession of the Republic of Crimea to the Russian Federation
... changed the conflict into an international crisis. Russia played, according to the Western governments, an important part in the escalation of the conflict. According to Russian officials the internal conflict ...
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