DEAD box
Conserved requirement for DEAD box RNA helicase Gemin3 in Drosophila oogenesis
... The DEAD-box RNA helicase Gemin3 (also referred to as DP130 or DDX20) is a core member of the SMN (survival of motor neurons) complex ...other DEAD-box family members within the nine motifs ...
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An Essential Role for the Saccharomyces cerevisiae DEAD-Box Helicase DHH1 in G1/S DNA-Damage Checkpoint Recovery
... DED1, DEAD-box Previous studies have suggested associations between helicases with roles in mRNA export and translation Dhh1p and several proteins with roles in mRNA degra- initiation, respectively ...
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Alterations in the expression of DEAD box and other RNA binding proteins during HIV 1 replication
... certain DEAD box protein RNA helicases, DDX3 and DDX1, play an important role in the HIV infection cycle by facilitating the export of long, singly spliced or unspliced HIV RNAs from the nucleus via the ...
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DDX3 DEAD-Box RNA Helicase Inhibits Hepatitis B Virus Reverse Transcription by Incorporation into Nucleocapsids
... Experimental strategy. To search for host factors that bind to HBV Pol, we utilized affinity purification of HBV Pol fol- lowed by mass spectrometry to identify copurified host factors. A cell line that stably expresses ...
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Molecular identification and characterization of host DEAD-box RNA helicases that are associated with Turnip mosaic virus infection
... replication. DEAD-box RNA helicases (RHs) have been shown to play multiple roles in RNA metabolism, including remodeling RNA structures and promoting RNA-protein ...Arabidopsis DEAD- box RNA ...
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DDX3 DEAD-Box RNA Helicase Is a Host Factor That Restricts Hepatitis B Virus Replication at the Transcriptional Level
... DDX3 downregulates HBV RNA via transcriptional regula- tion. DDX3 has been implicated in the transcriptional regulation of several promoters (14–16). Thus, it is possible that DDX3 in- hibits viral RNA synthesis by ...
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Subsite-specific association of DEAD box RNA helicase DDX60 with the development and prognosis of oral squamous cell carcinoma
... novel DEAD box RNA helicase, is induced after a virus ...homolog DEAD box polypeptide 60-like (DDX60L) have recently been described as interferon-stimulated products upon a viral ...
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SpolvlgA is a DDX3/PL10-related DEAD-box RNA helicase expressed in blastomeres and embryonic cells in planarian embryonic development
... Planarian flatworms have an impressive regenerative power. Although their embryonic de- velopment is still poorly studied and is highly derived it still displays some simple character- istics. We have identified ...
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Centroid, a novel putative DEAD box RNA helicase maternal mRNA, is localized in the mitochondrial cloud in Xenopus laevis oocytes
... of DEAD- box RNA helicase consensus motifs and centroid showed that centroid contains motifs Q, I (Walker A), II (Walker B), which are involved in ATP binding and hydrolysis, motifs Ia, Ib involved in RNA ...
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A HIV 1 Tat mutant protein disrupts HIV 1 Rev function by targeting the DEAD box RNA helicase DDX1
... type Tat [37,45-47] or Nullbasic [37]. To pursue this idea, we used a proteomics-based approach and identified 46 host proteins that co-immunoprecipitated with Nullbasic. Many of the identified proteins can regulate Rev ...
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The Me31B DEAD Box Helicase Localizes to Postsynaptic Foci and Regulates Expression of a CaMKII Reporter mRNA in Dendrites of Drosophila Olfactory Projection Neurons
... Citation: Hillebrand J, Pan K, Kokaram A, Barbee S, Parker R and Ramaswami M (2010) The Me31B DEAD-box helicase localizes to postsynaptic foci and regulates expression of a CaMKII re[r] ...
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DEAD-box helicase 27 plays a tumor-promoter role by regulating the stem cell-like activity of human colorectal cancer cells
... DeaD-box helicase 27 plays a tumor-promoter role by regulating the stem cell-like activity of human colorectal cancer cells.. chunxing Yang 1, * Daojiang li 1, * Yang Bai 1 shenglei so[r] ...
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The DEAD box RNA helicase Vasa functions in embryonic mitotic progression in the sea urchin
... Its DEAD-box motif, its physical interaction with eIF5B and the observation that several proteins do not accumulate in Vasa-mutant flies suggests that it functions in translational regulation (Linder, 2003; ...
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The DEAD box RNA helicase Vad1 regulates multiple virulence associated genes in Cryptococcus neoformans
... The study of fungal regulatory networks is essential to the understanding of how these pathogens respond to host environmental signals with effective virulence-associated traits. In this study, a virulence-associated ...
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The DEAD box RNA helicase Ddx39ab is essential for myocyte and lens development in zebrafish
... the DEAD-box RNA helicase family have been shown to be involved in nearly all aspects of RNA metabolism, from transcription to mRNA ...of DEAD-box RNA helicases in a broader context, including ...
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Unexpected roles for DEAD box protein 3 in viral RNA sensing pathways
... The DEAD-box helicase DDX3X is a critical component of the TANK-binding kinase 1-dependent innate immune ...DExD/H box RNA helicases: multifunctional proteins ...
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Involvement of a Toxoplasma DEAD-box RNA Helicase in Post-transcriptional Gene Regulation
... The transgenic TgHoDI-SG and TgHoDI-YFP strains exhibited similar doubling time in comparison to the parental strain, which showed an approximate replication time of approximately 8 hours for the two transgenic clones, ...
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DDX3 DEAD-Box RNA Helicase Is Required for Hepatitis C Virus RNA Replication
... DDX3, a DEAD-box RNA helicase, binds to the hepatitis C virus (HCV) core protein. However, the role(s) of DDX3 in HCV replication is still not understood. Here we demonstrate that the accumulation of both ...
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Regulation of Notch Signaling by an Evolutionary Conserved DEAD Box RNA Helicase, Maheshvara in Drosophila melanogaster
... ABSTRACT Notch signaling is an evolutionary conserved process that influences cell fate determination, cell proliferation, and cell death in a context-dependent manner. Notch signaling is fine-tuned at multiple levels and ...
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The Sole DEAD Box RNA Helicase of the Gastric Pathogen Helicobacter pylori Is Essential for Colonization
... the DEAD-box helicases distribution in the Epsilonpro- teobacteria class highlighted a striking feature: every member of the Campylobacter and Helicobacter genera, which included major pathogens such as ...
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