DEAD-box RNA Helicases
Molecular identification and characterization of host DEAD-box RNA helicases that are associated with Turnip mosaic virus infection
... replication. DEAD-box RNA helicases (RHs) have been shown to play multiple roles in RNA metabolism, including remodeling RNA structures and promoting RNA-protein ...
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Conserved requirement for DEAD box RNA helicase Gemin3 in Drosophila oogenesis
... The DEAD-box RNA helicase Gemin3 (also referred to as DP130 or DDX20) is a core member of the SMN (survival of motor neurons) complex ...other DEAD-box family members within the nine ...
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Centroid, a novel putative DEAD box RNA helicase maternal mRNA, is localized in the mitochondrial cloud in Xenopus laevis oocytes
... of RNA metabolism such as transcription, RNA splicing, ribosome bio- genesis, translation initiation and RNA transport and degradation and are found in all eukaryotes and most prokaryotes (Cordin et ...
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A HIV 1 Tat mutant protein disrupts HIV 1 Rev function by targeting the DEAD box RNA helicase DDX1
... groups: RNA splicing/ transport factors, folding/transport proteins, transcription regulators, translation factors, cellular organization/ cytoskeleton and cell ...the DEAD-box RNA ...
17
The Sole DEAD Box RNA Helicase of the Gastric Pathogen Helicobacter pylori Is Essential for Colonization
... DEAD-box RNA helicases are ubiquitous enzymes that constitute the largest family of RNA helicases (9, ...of RNA helicases is designated “DEAD-boxes” because ...
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Involvement of a Toxoplasma DEAD-box RNA Helicase in Post-transcriptional Gene Regulation
... The transgenic TgHoDI-SG and TgHoDI-YFP strains exhibited similar doubling time in comparison to the parental strain, which showed an approximate replication time of approximately 8 hours for the two transgenic clones, ...
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The DEAD box RNA helicase Ddx39ab is essential for myocyte and lens development in zebrafish
... The DEAD-box RNA helicase family is a large group of proteins characterized by the presence of an Asp-Glu-Ala-Asp (DEAD) motif that is highly conserved from bacteria to humans (Bleichert and ...
12
DDX3 DEAD-Box RNA Helicase Is Required for Hepatitis C Virus RNA Replication
... Since helicases are motor enzymes that use energy derived from nucleoside triphosphate hydrolysis to unwind double- stranded nucleic acids, the DDX3–core complex might unwind the HCV double-stranded RNA and ...
5
Xp54 and related (DDX6 like) RNA helicases : roles in messenger RNP assembly, translation regulation and RNA degradation
... The DEAD-box RNA helicase Xp54 is an integral component of the messenger ribonucleoprotein (mRNP) particles of Xenopus ...export, RNA stability and translational ...these helicases in ...
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Subsite-specific association of DEAD box RNA helicase DDX60 with the development and prognosis of oral squamous cell carcinoma
... of RNA helicases, with 37 members in humans ...synthesis, RNA splicing and modification, ribosome and spliceosome assembly, and the transcriptional regulation of the genes involved in DNA repair and ...
12
DEAD box helicase DP103 defines metastatic potential of human breast cancers
... in RNA helicases by 98% (80). Additionally, the helicase-dead mutant (GNT) also retained its ability to induce invasion in MDA-MB-231 cells (Supplemental Figure 8, A–C), demonstrating that the ...
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Alterations in the expression of DEAD box and other RNA binding proteins during HIV 1 replication
... the DEAD box proteins, we noted that two genes encoding DEAD box proteins, DDX18, a DEAD-box protein induced by Myc and Max [35] and DDX39, (or URH49), a DEAD-box ...
5
The QRxGRxGRxxxG motif of the vaccinia virus DExH box RNA helicase NPH-II is required for ATP hydrolysis and RNA unwinding but not for RNA binding.
... GxGKT box, the Glu and Asp moieties just downstream of the DExH box, and various constituents of the QRxGRxGRxxxG motif (see ...DNA helicases (15, 28), the yeast RAD3 DNA helicase (27), the potyvirus ...
8
Paieri, Francesca (2018): Expression of the plant Photosystem II core proteins in the cyanobacterium Synechocystis sp. PCC6803 and characterization of the DEAD-box RNA helicase RH50 of A. thaliana. Dissertation, LMU München: Fakultät für Biologie
... chloroplast DEAD-box RNA helicase RH39 plays an important role in the introduction of the hidden-brake in the 23S rRNA together with an unknown endonuclease (Nishimura et ...of RNA ...
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Unexpected roles for DEAD box protein 3 in viral RNA sensing pathways
... the DEAD-box family of RNA ...in RNA binding and RNA-dependent cellular processes ...of RNA metabolism in the cell, and a role for DDX3 in cell cycle control and apoptosis has ...
9
Remembering the Dead
... These aide-memoires are just further impediments for the poetic persona to move on from their grief. “The dead are the bradycardia of the earth,..” (7), slowing the passage of time, much as bradycardia slows the ...
5
RECQ helicases are deregulated in hematological malignancies in association with a prognostic value
... affecting HR actors are correlated with genomic in- stability in B cell cancers [48]. By their involvement in HR and also by their ability to resolve and to continue the normal fork replication after DNA damage or rep- ...
9
Helicases and DNA dependent ATPases of Sulfolobus solfataricus
... The proximity of all of the motifs to each other and the NTP implicates them all in nucleotide binding and hydrolysis and possibly the coupling of energy from hydrolysis to DNA unwinding, despite not all motifs making ...
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Both RIG-I and MDA5 RNA Helicases Contribute to the Induction of Alpha/Beta Interferon in Measles Virus-Infected Human Cells
... FIG. 2. IFN-  mRNA expression in H358 cells and knockdown clones after MV infection or transfection with MV leader RNA. (A) The parental H358 cells, the clone expressing a nontargeting luciferase siRNA (Luc), ...
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Defaming the Dead
... the dead by urging that there was no evidence that he sought to bring the family into disrepute “and induce them to break the ...a dead man who leaves no descendants or rel- atives can be libeled with ...
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