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Dedifferentiated Liposarcoma

Primary colonic well-differentiated / dedifferentiated liposarcoma of the ascending colon: a case report

Primary colonic well-differentiated / dedifferentiated liposarcoma of the ascending colon: a case report

... The resected specimen was approximately 6.5 × 4.0 × 3.2 cm (Fig. 2a, b), the center of the solid tumor being located in the middle of the resected specimen. Patho- logic examination revealed proliferating spindle cells ...

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Intraperitoneal dedifferentiated liposarcoma showing MDM2 amplification: case report

Intraperitoneal dedifferentiated liposarcoma showing MDM2 amplification: case report

... Dedifferentiated liposarcoma is a variant of liposarcoma with a worse prognosis and it most commonly occurs in the retroperitoneum, while an intraperitoneal location is extremely ...of ...

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Animal models of well-differentiated/dedifferentiated liposarcoma: utility and limitations

<p>Animal models of well-differentiated/dedifferentiated liposarcoma: utility and limitations</p>

... 1 Liposarcoma presents in 2 largest groups, indicated as well-differentiated liposarcoma (WDL) and dedifferentiated liposarcoma (DDL), in addition to the less frequent myxoid and pleomorphic ...

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Preclinical evaluation of potential therapeutic targets in dedifferentiated liposarcoma

Preclinical evaluation of potential therapeutic targets in dedifferentiated liposarcoma

... Sarcomas are rare cancers with limited treatment options. Patients are generally treated by chemotherapy and/or radiotherapy in combination with surgery, and would benefit from new personalized approaches. In this study ...

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Case Report Primary orbital dedifferentiated liposarcoma with leiomyosarcomatous and low-grade osteosarcomatous differentiation

Case Report Primary orbital dedifferentiated liposarcoma with leiomyosarcomatous and low-grade osteosarcomatous differentiation

... Abstract: Liposarcoma originating in the orbit is extremely ...a dedifferentiated lipo sarcoma arising from the orbit of a Chinese ...well-differentiated liposarcoma with focal areas of ...

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Paratesticular dedifferentiated liposarcoma with leiomyosarcomatous differentiation: a case report with a review of literature

Paratesticular dedifferentiated liposarcoma with leiomyosarcomatous differentiation: a case report with a review of literature

... were dedifferentiated liposarcoma (DL), and 1 showed a myxoid/round cell liposarcoma ...and dedifferentiated components that usually overlap with spindle/pleomorphic cell high-grade sarcoma or ...

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Scattered genomic amplification in dedifferentiated liposarcoma

Scattered genomic amplification in dedifferentiated liposarcoma

... was dedifferentiated liposarcoma with atypical fat cells, sclerosis, a spindle cell component, as well as a component of spindle cells with rhabdoid differentiation; no region compatible with a ...

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Case Report Retroperitoneal dedifferentiated liposarcoma with osteosarcomatous components: a case report

Case Report Retroperitoneal dedifferentiated liposarcoma with osteosarcomatous components: a case report

... well-differentiated liposarcoma (WDL), dedifferentiated liposarcoma (DDL), myxoid liposarcoma, round cell liposarcoma, and mixed-type liposarcoma ...

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Case Report Primary cardiac dedifferentiated liposarcoma with homologous and heterologous differentiation: a case report

Case Report Primary cardiac dedifferentiated liposarcoma with homologous and heterologous differentiation: a case report

... JL. Dedifferentiated liposarcoma with “homologous” lipoblastic (pleomorphic lipo- sarcoma-like) differentiation: clinicopathologic and molecular analysis of a series suggesting revised diagnostic ...

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Dedifferentiated liposarcoma of the gallbladder: first reported case

Dedifferentiated liposarcoma of the gallbladder: first reported case

... vides liposarcoma into four types: atypical lipomatous tumor (ALT), myxoid liposarcoma (MLS), pleomorphic liposarcoma (PL), and dedifferentiated liposarcoma (DL) ...

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Dedifferentiated liposarcoma with leukocytosis  A case report of G CSF producing soft tissue tumors, possible association with undifferentiated liposarcoma lineage

Dedifferentiated liposarcoma with leukocytosis A case report of G CSF producing soft tissue tumors, possible association with undifferentiated liposarcoma lineage

... of liposarcoma accompanied by leuko- cytosis and associated with G-CSF expression ...these liposarcoma cases was dedifferentiated liposarcoma in 4 cases [10-12] and pleomorphic ...

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Giant dedifferentiated liposarcoma of small bowel mesentery: a case report

Giant dedifferentiated liposarcoma of small bowel mesentery: a case report

... Dedifferentiated liposarcoma is a variant of liposarcoma having worse prognosis and higher risk of local recurrence than the well-differentiated ...

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High-dose continuous-infusion ifosfamide in advanced well-differentiated/dedifferentiated liposarcoma

High-dose continuous-infusion ifosfamide in advanced well-differentiated/dedifferentiated liposarcoma

... in liposarcoma, given their heterogeneity, being often made up of two components, a well differentiated and a dedif- ...the dedifferentiated components can be appreciated, since the former has the ...

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Identification of key genes and molecular mechanisms associated with dedifferentiated liposarcoma based on bioinformatic methods

Identification of key genes and molecular mechanisms associated with dedifferentiated liposarcoma based on bioinformatic methods

... Specifically, within the DEGs of DDLPS samples, several pathways were identified as being significantly enriched, including the PPAR signaling pathway, cell cycle pathway, and pyruvate [r] ...

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Primary cardiac dedifferentiated liposarcoma in a middle-aged female: a case report

Primary cardiac dedifferentiated liposarcoma in a middle-aged female: a case report

... DDLPS is one of the most common types of soft tissue sarcoma which represents over 60% of all liposarcoma [5] and is almost universally associated with amplifica- tion of chromosome segment 12q13–15, which carries ...

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miR-133a function in the pathogenesis of dedifferentiated liposarcoma

miR-133a function in the pathogenesis of dedifferentiated liposarcoma

... MiRNAs are evolutionarily conserved non-coding strands of RNA ~ 22 nucleotides in length that act as expression modulators of genes involved in fundamental cell processes, and their dysregulation have been impli- cated ...

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Case Report A case of dedifferentiated liposarcoma with well-differentiated liposarcomatous, inflammatory myofibroblastic tumor-like, and low- and high-grade osteosarcomatous components: common MDM2 amplification supporting divergent morphological change

Case Report A case of dedifferentiated liposarcoma with well-differentiated liposarcomatous, inflammatory myofibroblastic tumor-like, and low- and high-grade osteosarcomatous components: common MDM2 amplification supporting divergent morphological change of well-differentiated liposarcoma

... With respect to muscle mark- er positivity in the IMT-like component, it has recently been revealed that retroperi- toneal liposarcoma can be divided into different risk cat- egories according to muscle marker ...

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Case Report Retroperitoneal liposarcoma manifested as an inguinoscrotal mass: a case report

Case Report Retroperitoneal liposarcoma manifested as an inguinoscrotal mass: a case report

... a dedifferentiated liposarcoma in the inguinoscrotal ...giant liposarcoma that appeared as a dumbbell-shaped tumor extending from the retro- peritoneum to the scrotum through the inguinal ...

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Original Article Clinical outcomes of undifferentiated sarcomas are similar with that of other spindle cell sarcomas of specific histologic types: an institutional experience

Original Article Clinical outcomes of undifferentiated sarcomas are similar with that of other spindle cell sarcomas of specific histologic types: an institutional experience

... carcinoma in the form of high sarcomatoid car- cinoma should be considered. In this case, use of wide range immunohistochemical panel con- taining several antibodies for the detection of epithelial differentiation may be ...

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A unique dedifferentiated tumor of the retroperitoneum

A unique dedifferentiated tumor of the retroperitoneum

... differentiated liposarcoma and a spindle cell sarcoma with heterologous chondrosarcomatous ele- ments consistent with a dedifferentiated liposarcoma (Figure ...

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