Degenerative Diseases
EGF and the potassium channel Kv1.3 are promising pharmacological targets against neuro-degenerative diseases
... brain progenitor cells where participates in modulating their final fate. This review summarizes the major findings concerning Kv1.3 and neural stem cell modulation, emphasizing the combination of Kv1.3 with EGFR as ...
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Cantilever Transforaminal Lumbar Interbody Fusion for Upper Lumbar Degenerative Diseases (Minimum 2 Years Follow Up)
... primary diseases studied were disc herniation, ossification of posterior longitudinal ligament (OPLL), degenerative scoliosis, lumbar spinal canal stenosis, spondylolisthesis, and degeneration of adjacent ...
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Micronutrient, Genome Stability and Degenerative Diseases: Nutrigenomics Concept of Disease Prevention – An Overview
... of degenerative diseases and multiple micronutrient deficiency &their interaction with genes is powerfully established as influencing factor for causing DNA ...
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Association between Fas/FasL gene polymorphism and musculoskeletal degenerative diseases: a meta analysis
... from degenerative cell changes, influen- cing tissues or organs, which will gradually deteriorate over ...common degenerative diseases in musculoskeletal systems include intervertebral disc de- ...
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Suboptimal hydration remodels metabolism, promotes degenerative diseases, and shortens life
... many degenerative diseases, such as cognitive impairment and dementia (45–47), HF (48, 49), and CLD ...these diseases (49, 52, ...the diseases with elevated midlife serum sodium concentration ...
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Generating mouse models of degenerative diseases using Cre/lox mediated in vivo mosaic cell ablation
... Most degenerative diseases begin with a gradual loss of specific cell types before reaching a threshold for symptomatic onset. However, the endogenous regenerative capacities of different tissues are ...
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Is unilateral pedicle screw fixation superior than bilateral pedicle screw fixation for lumbar degenerative diseases: a meta-analysis
... lumbar degenerative diseases; Intervention: unilateral ped- icle screw fixation; Comparator: bilateral pedicle screw fix- ation; Outcomes: fusion rate, visual analog scale (VAS) at final follow-up, Oswestry ...
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Regenerative Medicine: Advances from Developmental to Degenerative Diseases
... has been limited by the lack of an adequate supply of cells, as the demand for donated tissues and organs by far outweighs the current and future clinical need. The advent of stem cell technologies has had a profound ...
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Alternative Medicine and Molecular Mechanisms in Chronic Degenerative Diseases
... chronic degenerative diseases. People with any of these diseases, accelerate the excessive pro- duction of free radicals and induce non-enzymatic glyca- tion of proteins and peroxidation of ...
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Non fusion procedure using PEEK rod systems for lumbar degenerative diseases: clinical experience with a 2 year follow up
... Lumbar degenerative diseases such as degenerative disc herniation, lumbar spinal stenosis, and lumbar instability syndrome exert a substantial impact on daily life and functional ...
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Is there a role for wine in cancer and the degenerative diseases of aging?
... Abstract: Population aging is associated with the increased incidence cancer and of degenerative diseases. Population aging is occurring on a global scale, with faster aging projected for the coming decades ...
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Correlation between Loss of Cervical Lordosis and Degenerative Diseases of the Sub-axial Cervical Spine Columns
... between degenerative process of each column of subaxial cervical spine and loss of cervical lordotic, but significant correlation was found between posterior listhesis and cervical kyphosis ...
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Sirtuin 1 mediates the obesity induced risk of common degenerative diseases: Alzheimer’s disease, coronary artery disease and type 2 diabetes
... several diseases including obesity, diabetes, atheroscle- rosis, and cancer, and PPARgamma agonists have been used successfully in the treatment of dyslipidemia and ...
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Pedicle screw fixation and posterior fusion for lumbar degenerative diseases: effects on individual paraspinal muscles and lower back pain; a single center, prospective study
... DLD: Degenerative lumbar disease; LBP: Lower back pain; MRI: Magnetic resonance imaging; FERCAP: Forum for Ethical Review Committees in Asia & the Western Pacific; EMG: Electromyography; BMI: Body mass index; ...
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Epigenetics mechanisms and degenerative diseases
... MicroRNAs [miRNAs] play a pivotal role in regula- tion of gene expression in inflammatory response. They are expressed mostly in tissue specific or developmental stage dependant manner. Nagata et al. injected miRNA15a ...
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The diagnostic value of soluble urokinase-type plasminogen activator receptor (suPAR) for the discrimination of vertebral osteomyelitis and degenerative diseases of the spine
... undetected diseases on suPAR levels cannot be excluded which may have an impact on the mean values because of the relatively small number of patients included in this single-center ...
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Obesity and Inflammation: A Way for Non- Communicable Degenerative Diseases
... From this point on, it is understood that there is a predicted relationship between higher secretion and high levels of cytokines in obese individuals, which predisposes to the risk o[r] ...
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Genetic architecture of retinal and macular degenerative diseases: the promise and challenges of next-generation sequencing
... A common-variant-based GWAS approach has not explained the complete genetic variance observed in com- plex traits. Missing heritability might be explained by rare to low frequency variants (minor allele frequency (MAF) ...
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Lipid Profile and Risk Factors of Cardiovascular Diseases in Adult Candidates for Lumbar Disc Degenerative Disease Surgery
... Disc Degenerative diseases (LDD) are among the most important causes of low back pain, and various environmental and genetic factors are involved in their development ...of degenerative Disc ...
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Is minimally invasive superior than open transforaminal lumbar interbody fusion for single-level degenerative lumbar diseases: a meta-analysis
... Minimally invasive transforaminal lumbar interbody fu- sion (MI-TLIF) was first introduced by Harms and Rolin- ger in the year of 1982 [1]. MI-TLIF has been used increasingly in lumbar degenerative diseases ...
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