Dengue Virus
Human T Lymphocytes Are Permissive for Dengue Virus Replication
... ABSTRACT Dengue virus (DV) infection can cause either a self-limiting flu-like dis- ease or a threatening hemorrhage that may evolve to shock and death. A variety of cell types, such as dendritic cells, ...
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Usefulness of dengue ns1 antigen as an early marker of dengue virus infection in a tertiary care hospital
... secondary dengue is low compared to that of primary dengue, due to formation of immune complexes with preexisting antibodies (Singapore study and Hu D et al, 2011), whereas some other studies have ...
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Characterization of dengue virus entry into HepG2 cells
... with dengue virus serotype 2 at MOI of 1 in presence or absence of the inhibitor following which cells were either treated with acid glycine (pH3) or subjected to three washes with ...increase virus ...
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Early T-Cell Responses to Dengue Virus Epitopes in Vietnamese Adults with Secondary Dengue Virus Infections
... acute dengue illness would be obtained by measuring ex vivo responses to a spectrum of dengue virus antigens in a patient population with a mixed HLA ...secondary dengue virus ...
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Discovery of Dengue Virus NS4B Inhibitors
... of dengue virus (DENV) alone cause 390 million human infections each year ...in dengue clinical trials, including balapiravir (a nu- cleoside inhibitor) (6), celgosivir (a cellular ␣ -glucosidase ...
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Immunization of mice with recombinant vaccinia virus expressing authentic dengue virus nonstructural protein NS1 protects against lethal dengue virus encephalitis.
... 4356-4363 0022-538X/90/094356-08$02.00/0 Copyright C 1990, American Society for Microbiology Immunization of Mice with Recombinant Vaccinia Virus Expressing Authentic Dengue Virus Nonstr[r] ...
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Suppression of Drug Resistance in Dengue Virus
... C virus polymerase (14) but also displays antiviral activity against dengue virus serotype 2 in cultured cells and in mice ...of dengue virus serotype 2 in BHK-21 cells is shown in ...
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Human antibody response to dengue virus: implications for dengue vaccine design
... Dengue virus (DENV) annually infects up to 390 million people living in tropical and subtropical areas ...large dengue epidemics due to its ability to efficiently transmit ...
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Dengue Virus Envelope Dimer Epitope Monoclonal Antibodies Isolated from Dengue Patients Are Protective against Zika Virus
... multiple dengue vaccine candidates are in phase II and III clinical trials, including a tetravalent vaccine that is currently approved for use in regions where ZIKV is emerging ...of dengue virus ...
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Development of a transmission model for dengue virus
... Dengue virus (DENV) is the most common arboviral in- fection of humans, infecting tens of millions of people each year in tropical areas [1]. There is presently no vac- cine available for DENV and reducing ...
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Mechanisms of dengue virus neutralization by antibody
... of virus strains over time and to study the evolution of DENV ...Although dengue virus infection is one of the major health concerns in the Indian subcontinent, the disease and its viruses remains ...
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Dengue virus infection induces autophagy: an in vivo study
... in dengue virus-infected mouse brain (Figure 4), which was consistent with the result of an in vitro investigation by Panyasrivanit et ...harboring dengue viruses fuses with the autophagosome to form ...
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Peptide inhibitors of dengue virus and West Nile virus infectivity
... influenza virus and human immunodeficiency virus (HIV), contain two prominent alpha ...Nile virus (WNV) and dengue virus (DENV), are class II viral fusion proteins comprised ...
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Comparison of PanBio Dengue Duo Enzyme-Linked Immunosorbent Assay (ELISA) and MRL Dengue Fever Virus Immunoglobulin M Capture ELISA for Diagnosis of Dengue Virus Infections in Southeast Asia
... MRL dengue fever virus IgM capture ELISA (MRL Diagnostics, Cypress, ...PanBio Dengue Duo IgM capture and IgG capture ELISA (PanBio Pty ...active dengue virus ...acute dengue ...
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Characterization of Dengue Virus Complex-Specific Neutralizing Epitopes on Envelope Protein Domain III of Dengue 2 Virus
... The surface of the mature dengue virus (DENV) particle is covered with 180 envelope (E) proteins arranged as homodimers that lie relatively flat on the virion surface. Each monomer consists of three domains ...
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Determinants of Dengue Virus NS4A Protein Oligomerization
... Flavivirus NS4A protein induces host membrane rearrangement and functions as a replication complex component. The molec- ular details of how flavivirus NS4A exerts these functions remain elusive. Here, we used ...
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Membrane Topology and Function of Dengue Virus NS2A Protein
... flavi- virus NS2A on the ER membrane. Using dengue virus (DENV) NS2A as a model, we show that (i) the N-terminal 68 amino acids are located in the ER lumen, with one segment (amino acids 30 to 52) ...
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Inhibition of Dengue Virus Polymerase by Blocking of the RNA Tunnel
... of dengue virus infect 50 to 100 million people each year, with approximately 500,000 cases developing into life-threatening dengue hemorrhage fever (DHF) and dengue shock syndrome (DSS), ...
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Dengue Virus- The Life Threatening Virus
... considers dengue as a major global public healthchallenge in the tropic and subtropical ...nations. Dengue has seen a 30-fold upsurge worldwidebetween 1960 and 2010, due to increased population growth rate, ...
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Dengue Virus- The Life Threatening Virus
... in dengue viruses and climate change might be responsible for theobserved increase in dengue burden across India 47, 48 ...of dengue and to a lesser extent on understandingthe relevance of climatic ...
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