(deoxy)thymidine kinase
Thymidine plaque autoradiography of thymidine kinase positive and thymidine kinase negative herpesviruses
... Herpes simplex virus thymidine kinase expression in trigeminal ganglion infection: correlation of enzyme activity with ganglion virus titer and evidence of in vivo complementation.. Alte[r] ...
6
Human Thymidine Kinase Can Functionally Replace Herpes Simplex Virus Type 1 Thymidine Kinase for Viral Replication in Mouse Sensory Ganglia and Reactivation from Latency upon Explant
... 1 thymidine kinase exhibits a strikingly broad substrate ...human thymidine kinase, deoxycytidine as does human deoxycytidine kinase, the cytosolic kinase whose amino acid ...
6
Mass action models versus the Hill model: An analysis of tetrameric human thymidine kinase 1 positive cooperativity
... human thymidine kinase 1 (TK1) activity data were formed as pairs of plausible hypotheses that per site activities and binary dissociation constants are equal within contiguous stretches of the number of ...
17
Origin of Thymidine Kinase in Adenovirus-Infected Human Cell Lines
... Confluent monolayer cultures of KB and HeLa BU25 cells were 446 Downloaded from http://jvi.asm.org/ on November 11, 2019 by guest Human adenovirus type 5 enhances the thymidine kinase ac[r] ...
5
Mapping and identification of the vaccinia virus thymidine kinase gene.
... This DNA fragment encodes four known early polypeptides, and to determine which of these was thymidine kinase, early VV mRNA was fractionated by sucrose gradient centrifugation and used [r] ...
7
Transfer of Thymidine Kinase to Thymidine Kinaseless L Cells by Infection with Ultraviolet-Irradiated Herpes Simplex Virus
... 813-820 Copyright 1971 American Society for Microbiology Transfer of Thymidine Kinase to Thymidine Kinaseless L Cells by Infection with Ultraviolet-Irradiated Herpes Simplex Virus Recei[r] ...
8
Selective assay for herpes simplex viruses expressing thymidine kinase.
... Introduction of herpes simplex virus thymidine kinase gene into mouse cells using virus DNA or transformed cell DNA.. Transfer of thymidine kinase to thymidine kinaseless L cells by infe[r] ...
7
Genetic and biochemical characterization of the thymidine kinase gene from herpesvirus of turkeys.
... A conserved open reading frame that overlaps the herpes simplex virus thymidine kinase gene is important for viral growth in cell culture.. Induction of both thymidine and deoxycytidine [r] ...
6
Origin of the Thymidine Kinase Induced by Polyoma Virus in Productively Infected Cells
... Origin of the Thymidine Kinase Induced by Polyoma Virus in Productively Infected Cells CLAUDIO BASILICO,1 YUTAKA MATSUYA,2 AND HOWARD GREEN Department of Pathology, New York Uniiversity [r] ...
6
Identification of the thymidine kinase gene of feline herpesvirus: use of degenerate oligonucleotides in the polymerase chain reaction to isolate herpesvirus gene homologs.
... Nucleotide sequence of the herpes simplex virus type 2 HSV-2 thymidine kinase gene and predicted amino acid sequence of the thymidine kinase polypeptide and its comparison with the HSV-1[r] ...
10
Random mutagenesis of the thymidine kinase gene of varicella-zoster virus.
... Nucleotide and predicted amino acid sequences of the Marek's disease virus and turkey herpesvirus thymidine kinase genes; comparison with thymidine kinase genes of other herpesviruses.. [r] ...
7
Isolation of mutants of bacteriophage T4 unable to induce thymidine kinase activity. II. Location of the structural gene for thymidine kinase.
... This contrasts to the finding that the total thymidine kinase activity in extracts prepared from cells infected with phage able to induce thymidine kinase is only twice as great as the a[r] ...
6
Isolation of Mutants of Bacteriophage T4 Unable to Induce Thymidine Kinase Activity
... coli cells lacking thymidine kinase are grown in the presence of BUdR and light and are infected with T4, phage lacking the ability to induce thymidine kinase should be able to form prog[r] ...
6
Induction of thymidine kinase and DNase in varicella-zoster virus-infected cells and kinetic properties of the virus-induced thymidine kinase.
... 1 Induction of Thymidine Kinase and DNase in Varicella-Zoster Virus-Infected Cells and Kinetic Properties of the VirusInduced Thymidine Kinase Received for publication 23 January 1979 Th[r] ...
6
A conserved open reading frame that overlaps the herpes simplex virus thymidine kinase gene is important for viral growth in cell culture.
... Nucleotide sequence of the herpes simplex virus type 2 HSV-2 thymidine kinase gene and predicted amino acid sequence of thymidine kinase polypeptide and its comparison with the HSV-1 thy[r] ...
5
siRNA Targeting of Thymidylate Synthase, Thymidine Kinase 1 and Thymidine Kinase 2 as an Anticancer Therapy: A Combinatorial RNAi Approach
... only in combination with higher 5FUdR concentrations that reduce TS activity and cell viability more profoundly. These possibilities are appropriate for future investigation. Issues such as those discussed above might be ...
183
Control of expression of the vaccinia virus thymidine kinase gene.
... ANDREW BALL Biophysics Laboratory, Graduate School, and Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706 m[r] ...
9
Late-onset thymidine kinase 2 deficiency: a review of 18 cases
... The clinical features and results of the diagnostic tests described in our series show a homogeneous phenotypic pattern in late-onset TK2 deficiency consisting of pro- gressive proximal [r] ...
10
Encapsidation and expression of the herpes thymidine kinase gene in polyoma virus.
... At the indicated times, 5 ml of viral supernatant extracts were prepared, and 0.1 ml was assayed for A the ability to produce at 38°C viral T-antigen by extracts of PY60TK- plus TS25B-co[r] ...
9
Epstein-Barr virus-associated thymidine kinase.
... To rule out the possibility that this new TK was induced by mycoplasma contamination of the P3HR-1 cells from which we concentrated EBV, we offer the following results: i none of the cel[r] ...
6