DEPENDENT PROTEIN-KINASE
sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase.
... sckl, a High Copy Number Suppressor of Defects in the CAMP-Dependent Protein Kinase Pathway in Fission Yeast, Encodes a Protein Homologous.. to the Saccharomyces cer[r] ...
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Reduced Activity of Mutant Calcium Dependent Protein Kinase 1 Is Compensated in Plasmodium falciparum through the Action of Protein Kinase G
... a protein kinase with one with a different side ...bumped kinase inhibitors ...calcium-dependent protein kinase 1 ...of protein kinase G ...another kinase ...
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Autoantibodies to DNA dependent protein kinase Probes for the catalytic subunit
... DNA-dependent protein kinase (DNA-PK) is an important nuclear enzyme which consists of a catalytic subunit known as DNA-PKcs and a regulatory component identified as the Ku ...Ku protein, ...
6
Phosphoinositide Metabolism Links cGMP- Dependent Protein Kinase G to Essential Ca (2+) Signals at Key Decision Points in the Life Cycle of Malaria Parasites
... dynamin-related protein B (DrpB) or the VPS10/sortilin homolog TgSORTLR, proteins destined for micronemes fail to be targeted from the Golgi to secretory organelles and instead enter the constitutive secretion ...
15
DNA–dependent protein kinase in telomere maintenance and protection
... The circular types of extrachromosomal telomeric DNA, including double – stranded T – circles and the single – stranded C – circles, are commonly identified in cells with long telomeres through telomerase–mediated ...
14
Relationship of the cAMP-dependent protein kinase pathway to the SNF1 protein kinase and invertase expression in Saccharomyces cerevisiae.
... Suppression of the R a f phenotype is not due to restoration of invertase expression: T h e snfl and snf4 mutants are defective i n growth on raffinose at least i n [r] ...
10
Plasmodium falciparum Calcium Dependent Protein Kinase 2 Is Critical for Male Gametocyte Exflagellation but Not Essential for Asexual Proliferation
... (KO-C1) and clone C13 (KO-C13) parasite (iii) is shown. A common forward oligonucleotide (F3) specific to the 5=-UTR of PfCDPK2 was used for all of the amplifications. Reverse oligonucleotide R1 specific for the deleted ...
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Toxoplasma gondii Cyclic AMP Dependent Protein Kinase Subunit 3 Is Involved in the Switch from Tachyzoite to Bradyzoite Development
... of kinase domain of TgPKAc1 and ...the kinase do- main of TgPKAc3 (TgPKAc3 ⌬ 120) were cloned into the pcDNA3 mam- malian expression ...The protein kinase assay was performed with the ...
12
The Role of Dbf4-Dependent Protein Kinase in DNA Polymerase ζ-Dependent Mutagenesis in Saccharomyces cerevisiae
... cdc7 kinase-dead (KD) mutant (Hollingsworth et ...Dbf4-dependent kinase (DDK) is conserved from yeast to humans and is composed of the Cdc7 kinase catalytic and Dbf4 regulatory ...for ...
12
Integrin Linked Kinase Is a Functional Mn2+ Dependent Protein Kinase that Regulates Glycogen Synthase Kinase 3β (GSK 3β) Phosphorylation
... active kinase is important with regard to the interpretation of a recent genetic study in which knock-in of the K220M mutant resulted in a dramatic kidney development defect [45] likely due, at least in part, to ...
10
The Role of Ca2+/Calmodulin Dependent Protein Kinase II Alpha in Group 1 Metabotropic Glutamate Receptor Endocytosis and Signalling
... the generation of diacylglycerol and inositol phosphate (IP). CaMKIIα is a kinase that could contribute to the phosphorylation and desensitization of group I mGluR G protein coupling. We focused our ...
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Stress Granules Regulate Double Stranded RNA Dependent Protein Kinase Activation through a Complex Containing G3BP1 and Caprin1
... GFP-tagged protein was immunoprecipitated, and precipitates were analyzed by Western blotting with antibodies against GFP, Caprin1, and total ...GFP-tagged protein as described for panel ...
12
Regulation of hormone sensitive calcium influx by the adenylyl cyclase system in renal epithelial cells
... cAMP-dependent protein kinase with reduced affinity for cAMP and treatment with KT-5720, a specific cAMP-dependent protein kinase inhibitor, enhanced Ca influx to a degree ...
10
Hormone mediated down regulation of hepatic glutathione synthesis in the rat
... cAMP-dependent protein kinase (A-kinase) inhibited GSH synthesis from substrates (cysteine, ATP, glutamate, and glycine) by approximately 20% which was prevented by the A-kinase ...
11
In Vivo Activation of Protein Kinase A in Schizosaccharomyces pombe Requires Threonine Phosphorylation at Its Activation Loop and Is Dependent on PDK1
... Phosphoinositide-dependent protein kinase 1 (PDK1) plays a central role in cellular signaling by phos- phorylating members of the AGC family of ...includes protein kinase C (PKC), ...
12
Oligopeptide transporter PepT1 in Atlantic cod (Gadus morhua L ): cloning, tissue expression and comparative aspects
... putative protein of 729 amino ...PepT1 protein with zebrafish, bird and mammalian orthologs allowed detection of many structural features that are highly conserved among all the vertebrate proteins ...
14
A Protein Kinase A-Dependent Mechanism by Which Rotavirus Affects the Distribution and mRNA Level of the Functional Tight Junction-Associated Protein, Occludin, in Human Differentiated Intestinal Caco-2 Cells
... guanylate kinase (MAGuK) family of proteins comprising the zonula occludens 1 (ZO-1), ZO-2, and ZO-3 proteins (25, 26, 60), play a particular role in the orga- nization of the TJs ...
8
An investigation into the mecanisms mediating calcium ion stimulated ACTH secretion from AtT 20 anterior pituitary tumour cells
... GTP-blnding protein responsible for PLC activation), generation of DAG and subsequent PKC activation contributes to secretion from AtT-20 cells under these ...
265
The role of tau in neurodegeneration
... protein that does not readily aggregate into filaments, this matter has been difficult to assess in experimental models because of the resistance of tau to aggregate within an ideal time-frame for culture studies ...
19
Geminivirus-Induced Gene Silencing of the Arabidopsis RETINOBLASTOMA-RELATED
... Differentiation in all eukaryotic organisms begins with an exit from the cell cycle and depends on the proper coordination of spatial and temporal events. Animal cells enter and exit the cell cycle during G1, and whether ...
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