Derivation and validation
Derivation and validation of a simple clinical bedside score (ATLAS) for Clostridium difficile infection which predicts response to therapy
... the derivation cohort, the best discrimination and correlation with cure was seen with a five-component ATLAS score (age, treatment with systemic antibiotics, leukocyte count, albumin and serum creatinine as a ...
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Multicenter derivation and validation of an early warning score for acute respiratory failure or death in the hospital
... Methods: This was an observational study of adults admitted to four hospitals in 2013 or a fifth hospital in 2017. Clinical data were extracted from the EHRs. The 2013 patients were randomly split 50:50 into a ...
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Predicting hospital stay, mortality and readmission in people admitted for hypoglycaemia: prognostic models derivation and validation
... Characteristics of the remaining admissions with complete data, by outcome and sample, are reported in Table 1. No major differences were found between the derivation and val- idation samples. A large proportion ...
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Derivation and validation phase for the development of clinical prediction rules for rehabilitation in chronic nonspecific low back pain patients: study protocol for a randomized controlled trial
... Third, we aim to include a sufficiently large sample, based on a power analysis. Hicks et al. [16] included 54 patients in their study but no power analysis is men- tioned in their paper. If there are not enough patients ...
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<p>Derivation and Validation of a Risk Prediction Model for Vancomycin-Associated Acute Kidney Injury in Chinese Population</p>
... Methods: A retrospective cohort study was performed. A total of 524 hospitalized patients treated with vancomycin were included in this study. They were divided into derivation cohort (n=341) and externally ...
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Derivation and validation of a clinical prediction rule for sleep apnoea syndrome for use in primary care
... The sensitivity, specificity, PPV, and NPV for the different cut-off points on the scale are provided in Table 5. To guarantee a high sensitivity, and therefore the detection of patients who require treat- ment, cut-off ...
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Predicting cardiovascular intensive care unit readmission after cardiac surgery: derivation and validation of the Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease (APPROACH) cardiovascular intensive care unit clinical prediction model from a registry cohort of 10,799 surgical cases
... conducted only in specialized centers. Second, the model requires validation in an external dataset; however, an internal validation with bootstrapping was applied to the derivation model. Third, no ...
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Derivation and validation of a prognostic model for postoperative risk stratification of critically ill patients with faecal peritonitis
... the derivation, geographic and tem- poral validation cohorts, respectively), accompanied by a difference in the utilisation of renal replacement therapy (21, ...the derivation, geographic and ...
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Diagnosis of pulmonary hypertension with cardiac MRI: derivation and validation of regression models
... the derivation cohort and the second 303 as the validation cohort (Figure ...between derivation and validation cohorts (Table ...the derivation cohort and 45 in the validation ...
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Diagnosis of pulmonary hypertension with cardiac MRI: Derivation and validation of regression models
... the derivation cohort and the second 303 as the validation cohort (Figure ...between derivation and validation cohorts (Table ...the derivation cohort and 45 in the validation ...
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Derivation and validation of plasma endostatin for predicting renal recovery from acute kidney injury: a prospective validation study
... Results: Seventy-six of 198 (38.4%) patients failed to recover from AKI onset, with 41 in the derivation cohort and 35 in the validation cohort. Compared with NGAL and cystatin C, endostatin showed a better ...
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Derivation and validation of text search algorithms for renal and adrenal lesion identification in radiology text reports
... independent validation cohort showed that each point system was useful in determining the probability that a lesion truly existed (Table ...the derivation cohort, lesion score distribution was highly skewed ...
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Derivation and validation of clinical phenotypes for COPD: a systematic review
... the derivation of ...for derivation and validation [12], but none of the stud- ies validated the derived phenotypes in an external population, limiting the validity of these derived pheno- ...
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Derivation and validation of a prediction score for acute kidney injury secondary to acute myocardial infarction in Chinese patients
... Results: In this prediction score, risk score 1 point included hypertension history, heart rate > 100 bpm on admission, peak serum troponin I ≥ 100 μ g/L, and time from admission to coronary reperfusion > 120 min; ...
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Derivation and validation of a simple, accurate and robust prediction rule for risk of mortality in patients with Clostridium difficile infection
... The (simplified) prediction rule derived in this study was significant at classifying those patients with increased mortality in the derivation cohort (AUC = 0.704; P < 0.001; 95% CI: 0.619-0.790) and has been ...
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Derivation and validation of a search algorithm to retrospectively identify mechanical ventilation initiation in the intensive care unit
... the derivation and validation subsets, using peak inspiratory pressure (PIP) as the reference standard, was compared to assess timing of mechanical ventilation ...
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Early prediction of noninvasive ventilation failure in COPD patients: derivation, internal validation, and external validation of a simple risk score
... the derivation cohort, we found that 14 variables col- lected at initiation and 1–2 h of NIV were associated with NIV failure in univariate analyses (Table ...
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A household level score to predict the risk of tuberculosis among contacts of patients with tuberculosis: a derivation and external validation prospective cohort study
... Ventanilla derivation cohort consisted of 3301 households, and the Callao validation cohort consisted of 924 ...the derivation cohort and 2·23 (1·80) in the validation ...the derivation ...
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IPF patients are limited by mechanical and not pulmonary-vascular factors – results of a derivation-validation cohort study
... Summary statistics were reported as mean (standard de- viation) or counts as appropriate. The primary endpoint of the study was the bias and limits of agreement be- tween VEpeak measured during CPET with both direct MVV ...
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Derivation and validation of a model predicting the likelihood of vaginal birth following labour induction
... external validation therefore should be performed simultaneously in a large number of diverse cohorts, and factors responsible for variation in per- formance be ...
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