Detrusor Smooth Muscle
The electrophysiological properties of freshly isolated and cultured human and guinea-pig detrusor smooth muscle cells
... the detrusor smooth muscle (uncontrolled detrusor contraction, ...are detrusor instability and detrusor hyperreflexia. Detrusor instability occurs when the detrusor ...
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Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle
... Human detrusor samples were obtained from 41 pa- tients with an average age of 67 ± 10 years (mean ± S.D.; range 46–84 years old; 33 male and 8 female patients, Table 1). These specimens (1–2 cm width) were pre- ...
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Calcium currents in isolated human detrusor smooth muscle cells
... of detrusor instability remains ...on detrusor muscle strip contractility is also unknown and suggests an underlying difference between bladder and other smooth muscle ...determining ...
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Activation of bitter taste receptors (tas2rs) relaxes detrusor smooth muscle and suppresses overactive bladder symptoms
... Bitter taste receptors (TAS2Rs) are traditionally thought to be expressed exclusively on the taste buds of the tongue. However, accumulating evidence has indicated that this receptor family performs non-gustatory ...
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The characterisation of human detrusor smooth muscle cell cultures
... human detrusor smooth muscle by examining aspects of its physiological and biochemical ...of detrusor smooth muscle on tissue metabolism and ...
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Original Article Effect of glucose concentration on the expression of HSP27, CaD and TM proteins in rat detrusor smooth muscle cells
... Abstract: Objective: To investigate the effect of glucose concentration on the expression of proteins related to the contraction of rat detrusor smooth muscle cells (DSMCs). Methods: DSMCs were ...
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Adhesion molecules of detrusor muscle cells are influenced by a hypercholesterolemic diet or bladder outlet obstruction in a wistar rat model
... between detrusor smooth muscle cells are important in bladder dysfunction ...of muscle fibres that are caused by loss of intercellular adhesion has been demonstrated to be the morphological ...
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Two differentially structured collagen scaffolds for potential urinary bladder augmentation: proof of concept study in a Göttingen minipig model
... scaffold (OptiMaix 3D ® ), has already been used in differ- ent approaches of tissue engineering for diverse organs, such as esophagus, cartilage, vascular and smooth tis- sue, with promising outcomes [26–31]. The ...
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... All rats were anesthetized with isoflurane and euthanized. Urinary bladders were removed and sectioned horizontally at the level of the ureters. Two bladder strips were prepared x mm, taking special care to preserve ...
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Identification of atropine-and P2X1 receptor antagonist-reistant, neurogenic contractions of the urinary bladder
... Dysfunction of the urinary bladder is a major and ever expanding condition for which highly effective therapeutic options are still limited (de Groat and Yoshimura, 2001; Andersson and Wein, 2004; Fry et al., 2005). ...
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Prevention of smooth muscle cell outgrowth from human atherosclerotic plaque by a recombinant cytotoxin specific for the epidermal growth factor receptor
... on smooth muscle cell outgrowth from human atherosclerotic ...human smooth muscle cells proliferating in culture and can prevent smooth muscle cell outgrowth from "growth- ...
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Localization of P2X receptor subtypes 2, 3 and 7 in human urinary bladder
... the muscle layer. This observation was confirmed by the low correlation between vimentin and P2X7 immunore- activity in the smooth muscle layer of the human urinary bladder (Fig. 1c-d). By ...
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Conceptual Anatomical consideration of peśī regarding Human Female Body Constitution with its Applied Relevance
... Suśruta, Aṣṭāṃga hṛdaya, Bhāvaprakāśa, Śārṅgadhara has described about 500 muscles and Caraka has described 400 muscles. This mentioned number is denoted for the group of muscle having general consitiutional ...
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Immune interferon inhibits proliferation and induces 2' 5' oligoadenylate synthetase gene expression in human vascular smooth muscle cells
... Proliferation of vascular smooth muscle cells (SMC) contributes to formation of the complicated human atherosclerotic plaque. These lesions also contain macrophages, known to secrete SMC mitogens, and T ...
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Nicotinamide Riboside and the Aortic Response to Angiotensin II Infusion in Mice
... Animal and emerging human data have demonstrated that there is a progressive NAD + decline over the course of an organism’s lifespan. The reason for this decline appears to be multifaceted, with evidence of increased NAD ...
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Myolipoma Affecting the Erector Spinae: A Case Report in a Child
... well-differentiated smooth muscle tissue. The smooth muscle nature of the nonfatty component was demonstrated by a diffuse and strong immunoreactivity for smooth muscle actin and ...
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CArG elements control smooth muscle subtype–specific expression of smooth muscle myosin in vivo
... Expression of smooth muscle myosin heavy chain (SM-MHC) is tightly controlled depending on the differentiated state of smooth muscle cells (SMCs). To better understand the mechanisms that reg- ...
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Patent ductus arteriosus in mice with smooth muscle specific Jag1 deletion
... for smooth muscle cells (orange, anti-SM22a antibody) and endothelial cells (green, anti- PECAM1 antibody) revealed reduced vascular smooth muscle cell differentiation in the ductus arteriosus ...
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Gastrointestinal stromal tumour and hypoglycemia in a Fjord pony: Case report
... for smooth muscle actin (mouse monoclonal antihuman smooth muscle actin visualized by staining with AEC (3- amino-9ethylcarbazole) labelled secondary antibody, Dako Cytomation, Glostrup, ...
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MicroRNAs in cardiovascular disease: from pathogenesis to prevention and treatment
... The let-7 family of miRNAs was first identified through forward genetics as a regulator of developmental timing in C. elegans (51), but has been shown to exert a powerful effect on growth and metabo- lism in mammals ...
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