Dextran sodium sulfate
Effectiveness of Ricinus communis root extract against dextran sodium sulfate induced ulcerative colitis in rats
... (b) dextran sodium sulfate induced colitis rats with extensive mucosal damage and inflammation, (c) 5- Aminosalicylic acid (500 mg/kg) treated rats with mild mucosal damage and inflammation, (d) ...
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Interleukin 1α-Deficient Mice Have an Altered Gut Microbiota Leading to Protection from Dextran Sodium Sulfate-Induced Colitis
... moderate dextran sodium sulfate (DSS)-induced colitis compared to that of wild-type (WT) mice, characterized by reduced inflammation and complete healing, as shown by parameters of weight loss, ...
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Increased sensitivity to dextran sodium sulfate colitis in IRE1β deficient mice
... dextran sodium sulfate (DSS; mol wt = 40,000; lot number 7359C; ICN Biomedicals, Aurora, Ohio, USA) dissolved in the drinking water (3.5% wt/vol) (38, 39). In experiments not shown here, we ...
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Dextran sodium sulfate inhibits the activities of both polymerase and reverse transcriptase: lithium chloride purification, a rapid and efficient technique to purify RNA
... Background: Dextran sodium sulfate (DSS) is commonly used in mouse studies to induce a very reproducible colitis that effectively mimics the clinical and histological features of human inflammatory ...
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THE EFFECT OF MAHKOTA DEWA (PHALERIA MACROCARPA) (SCHEFF.) FRUIT PERICARP EXTRACT ON COX-2 and β-CATENIN EXPRESSION IN MICE COLON INDUCED BY DEXTRAN SODIUM SULFATE
... Dextran sodium sulphate (DSS) 2% purchased from Regent Science Industry Ltd, Hongkong is given through drinking water for 7 days and then punctuated with 7 days without administration of ...
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Ferrous sulfate, but not iron polymaltose complex, aggravates local and systemic inflammation and oxidative stress in dextran sodium sulfate-induced colitis in rats
... Dawley rats, aged 6 weeks old and weighing 200–250 g, at the Laboratory of Experimental Medicine, Hospital Aléman, Buenos Aires, Argentina. The rats were housed in a temperature-controlled room at 22 ° C ± 2 ° C and were ...
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Original Article Effect of Torin 1 on suppressing inflammation in mice with dextran sodium sulfate-induced colitis
... of dextran sulphate sodium (DSS) in mice induces colitis that resembles human UC and the resulting pathological condi- tions correspond very well to human ...
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Absence of bacterially induced RELMβ reduces injury in the dextran sodium sulfate model of colitis
... Although inflammatory bowel disease (IBD) is the result of a dysregulated immune response to commensal gut bacteria in genetically predisposed individuals, the mechanism(s) by which bacteria lead to the develop- ment of ...
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Dendrophthoe pentandra (L ) Miq extract effectively inhibits inflammation, proliferation and induces p53 expression on colitis associated colon cancer
... % dextran sodium sulfate (DSS) in a cycle protocol, each cycle consisted of seven days of 5 % DSS in the drinking water and followed by seven days of regular ...
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Comparison of two models of inflammatory bowel disease in rats
... Objectives. The aim of this study was to develop 2 affordable models of IBD in rats and to compare them. Material and methods. We produced IBD in rats using either dextran sodium sulfate (DSS) or 2, ...
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Invitro and invivo pharmacological studies using chitosan
... The mammalian gastrointestinal tract is continuously exposed to numerous bacteria as well as food-derived and environmental toxins and, as such, is highly vulnerable to disease. Two major inflammatorybowel diseases (IBD) ...
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The Role of Lactic Acid Bacteria in the Pathophysiology and Treatment of Irritable Bowel Syndrome (IBS)
... The Role of Lactic Acid Bacteria in the Pathophysiology and Treatment of Irritable Bowel Syndrome IBS croflora but Does not Heal Chronic Dextran-Sodium Sulfate-Induced Colitis or Reinfor[r] ...
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Colon-targeted delivery of cyclosporine A using dual-functional Eudragit<sup>®</sup> FS30D/PLGA nanoparticles ameliorates murine experimental colitis
... UC, ulcerative colitis; GIT, gastrointestinal tract; CSA, cyclosporine A; NPs, nanoparticles; IBD, inflammatory bowel disease; DSS, dextran sodium sulfate; TNBS, trinitrobenzene–[r] ...
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The ω-3 polyunsaturated fatty acids prevented colitis-associated carcinogenesis through blocking dissociation of β-catenin complex, inhibiting COX-2 through repressing NF-κB, and inducing 15-prostaglandin dehydrogenase
... azoxymethane-initiated, dextran sodium sulfate- promoted CACs, as well as significant preservation of 15-hydroxyprostaglandin dehydrogenase (15-PGDH) and significant inhibition of Cyclooxyganase-2 ...
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Effect of exercise on chemically-induced colitis in adiponectin deficient mice
... with dextran sodium sulfate (DSS)-induced colitis [27], however, given that the greatest overall ben- efits of exercise training observed in both the general population and in other chronic ...
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Tanshinone IIA ameliorates dextran sulfate sodium-induced inflammatory bowel disease via the pregnane X receptor
... 12% sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and was subsequently transferred electrophoretically to a polyvinylidene fluoride ...
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Article: Dextran sulfate sodium-induced colitis mice up-regulated extracellular matrix tenascin-C
... Abstract: Tenascin-C, an extracellular matrix glycoprotein, expresses high level during embryogenesis and almost absent during the normal postnatal life. However, it is re-appeared in a diverse condition such as tissue ...
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Original Article Chebulagic acid reduces inflammation and regulates enteric glial cells in mouse models of dextran sulfate sodium-induced colitis
... In summary, CA treatment can effectively re- duce inflammation and improve glial function in mouse models of dextran sulfate sodium- induced colitis. However, this study did not eval- uate S100β ...
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TSG-6 released from intraperitoneally injected canine adipose tissue-derived mesenchymal stem cells ameliorate inflammatory bowel disease by inducing M2 macrophage switch in mice
... DSS: Dextran sulfate sodium; ELISA: Enzyme-linked immunosorbent assay; FITC: Fluorescein isothiocyanate; GAPDH: Glyceraldehyde 3-phosphate dehydrogenase; IACUC: Institutional Animal Care and Use ...
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Red Seaweed Eucheuma cottonii Ethanol Extract
... curcumin in dextran sulfate sodium (dss)-induced ulcerative colitis murine model. Defining the microbial transcriptional response to colitis[r] ...
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