dextran sulfate sodium
Gallic acid attenuates dextran sulfate sodium-induced experimental colitis in BALB/c mice
... Abstract: Gallic acid (GA) is a polyhydroxy phenolic compound that has been detected in various natural products, such as green tea, strawberries, grapes, bananas, and many other fruits. In inflammatory bowel disease, ...
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Original Article Chebulagic acid reduces inflammation and regulates enteric glial cells in mouse models of dextran sulfate sodium-induced colitis
... In summary, CA treatment can effectively re- duce inflammation and improve glial function in mouse models of dextran sulfate sodium- induced colitis. However, this study did not eval- uate S100β ...
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Umbilical cord mesenchymal stem cells modulate dextran sulfate sodium induced acute colitis in immunodeficient mice
... BiP: binding immunoglobulin protein; DAI: disease activity index; DSS: dextran sulfate sodium; ER: endoplasmic reticulum; IBD: inflammatory bowel diseases; MMP: matrix metalloproteinase;[r] ...
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Knockout of the c-Jun N-terminal Kinase 2 aggravates the development of mild chronic dextran sulfate sodium colitis independently of expression of intestinal cytokines TNFα, TGFB1, and IL-6
... The aim of this study was to examine the function of JNKs by using a low-dose dextran sulfate sodium (DSS) model in JNK1 knockout mice (Mapk8–/–), JNK2 knockout mice (Mapk9–/–), and wi[r] ...
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Article: Dextran sulfate sodium-induced colitis mice up-regulated extracellular matrix tenascin-C
... Abstract: Tenascin-C, an extracellular matrix glycoprotein, expresses high level during embryogenesis and almost absent during the normal postnatal life. However, it is re-appeared in a diverse condition such as tissue ...
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Tanshinone IIA ameliorates dextran sulfate sodium-induced inflammatory bowel disease via the pregnane X receptor
... 12% sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and was subsequently transferred electrophoretically to a polyvinylidene fluoride ...
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TSG-6 released from intraperitoneally injected canine adipose tissue-derived mesenchymal stem cells ameliorate inflammatory bowel disease by inducing M2 macrophage switch in mice
... DSS: Dextran sulfate sodium; ELISA: Enzyme-linked immunosorbent assay; FITC: Fluorescein isothiocyanate; GAPDH: Glyceraldehyde 3-phosphate dehydrogenase; IACUC: Institutional Animal Care and Use ...
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Inflammation associated lymphangiogenesis: a double edged sword?
... the dextran sulfate sodium colitis model (67, 68), suggesting that lymphatic vessels are functionally important for the resolution of bowel inflamma- ...
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B Cells with Regulatory Function in Animal Models of Autoimmune and Non Autoimmune Diseases
... Dextran sulfate sodium-induced intestinal injury is more severe in CD19 −/− mice where B10 cells are absent than in wild type mice [49], suggesting these inflammatory responses are negatively ...
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Original Article Effect of Torin 1 on suppressing inflammation in mice with dextran sodium sulfate-induced colitis
... Abstract: The etiology of inflammatory bowel diseases (IBDs), such as ulcerative colitis (UC) and Crohn’s disease (CD), still remains unknown. It is also has great importance to develop new therapeutic strategies for the ...
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Adiponectin and adiponectin receptor 1 overexpression enhance inflammatory bowel disease
... Methods: We generated porcine AdipoR1 transgenic mice (pAdipoR1 mice) and induced murine colitis using dextran sulfate sodium (DSS) to study the potential role of AdipoR1 in inflammatory[r] ...
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Caffeic acid ameliorates colitis in association with increased Akkermansia population in the gut microbiota of mice
... Emerging evidence shows that dietary agents and phytochemicals contribute to the prevention and treatment of ulcerative colitis (UC). We first reported the effects of dietary caffeic acid (CaA) on murine experimental ...
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Red Seaweed Eucheuma cottonii Ethanol Extract
... curcumin in dextran sulfate sodium (dss)-induced ulcerative colitis murine model. Defining the microbial transcriptional response to colitis[r] ...
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PubMedCentral-PMC5319916.pdf
... (AOM)/Dextran Sulfate Sodium (DSS)-induced colon cancer model, intestine-specific Sirt1 heterozygous deletion mice (Villin-Cre + /Sirt1 flox/+ , Sirt1 iHet) developed significantly more and larger ...
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In Vitro and In Vivo Evaluations of Sodium Lauryl Sulfate and Dextran Sulfate as Microbicides against Herpes Simplex and Human Immunodeficiency Viruses
... lauryl sulfate (SLS) is a sulfated surfactant that denatures membrane proteins of cells and ...hand, dextran sulfate (DS) is a polysul- fated carbohydrate which has been shown to inhibit in vitro the ...
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THE EFFECT OF MAHKOTA DEWA (PHALERIA MACROCARPA) (SCHEFF.) FRUIT PERICARP EXTRACT ON COX-2 and β-CATENIN EXPRESSION IN MICE COLON INDUCED BY DEXTRAN SODIUM SULFATE
... Dextran sodium sulphate (DSS) 2% purchased from Regent Science Industry Ltd, Hongkong is given through drinking water for 7 days and then punctuated with 7 days without administration of ...
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Effectiveness of Ricinus communis root extract against dextran sodium sulfate induced ulcerative colitis in rats
... (b) dextran sodium sulfate treated model control rat colon, (c) 5- Aminosalicylic acid (500 mg/kg) treated rat colon, (d) Ricinus communis root extract (RCRE) (250 mg/kg) treated rat colon, and (e) ...
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Ferrous sulfate, but not iron polymaltose complex, aggravates local and systemic inflammation and oxidative stress in dextran sodium sulfate-induced colitis in rats
... ferrous sulfate treatment caused significant worsening of these ...ferrous sulfate, iron polymaltose complex caused less or no additional oxidative stress in the colon and liver compared to colitic animals ...
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Increased sensitivity to dextran sodium sulfate colitis in IRE1β deficient mice
... dextran sodium sulfate (DSS; mol wt = 40,000; lot number 7359C; ICN Biomedicals, Aurora, Ohio, USA) dissolved in the drinking water (3.5% wt/vol) (38, 39). In experiments not shown here, we ...
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Detection of a fluorescent-labeled avidin-nucleic acid nanoassembly by confocal laser endomicroscopy in the microvasculature of chronically inflamed intestinal mucosa
... 8–10 weeks) by using multiple cycles of dextran sodium sul- fate (DSS, 40 kDa, Sigma-Aldrich, St Louis, MO, USA). We performed preliminary optimization experiments to identify the optimal DSS dose and ...
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