Dextran sulfate sodium (DSS)
Fermented barley and soybean (BS) mixture enhances intestinal barrier function in dextran sulfate sodium (DSS) induced colitis mouse model
... 5% dextran sulfate sodium (DSS) drinking water to induce ...using DSS-treated Caco-2 cells by assessing ZO-1 immunofluorescence staining and Western blotting and in vivo by measuring ...
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Soybean and fish oil mixture increases IL-10, protects against DNA damage and decreases colonic inflammation in rats with dextran sulfate sodium (DSS) colitis
... by DSS was significantly less severe in group SF, showing that the mixture of fish oil and soybean oil balanced the w6:w3 PUFA ratio (2:1) and improved colonic inflamma- ...
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Knockout of the c-Jun N-terminal Kinase 2 aggravates the development of mild chronic dextran sulfate sodium colitis independently of expression of intestinal cytokines TNFα, TGFB1, and IL-6
... The DSS concentration of 1% for induction of mild chronic colitis was determined in previous studies (data not shown) and is suitable for experimental ...of DSS treatment (molecular weight 36–44 kDa; MP ...
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Regulatory effect of Garidisan on dysbiosis of the gut microbiota in the mouse model of ulcerative colitis induced by dextran sulfate sodium
... models, DSS- induced colitis model is widely used because of its sim- plicity and many similarities with human ulcerative col- ...itis. DSS carries a highly negative charge contributed by sulfate ...
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Umbilical cord mesenchymal stem cells modulate dextran sulfate sodium induced acute colitis in immunodeficient mice
... acute DSS colitis, suggesting that T cells, B cells and natural killer cells are not required for disease onset, and that the acute disease may be driven more by neutrophils or other innate immune cell types, in ...
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Interplay between craniofacial stem cells and immune stimulus
... cell; DSS: Dextran sulfate sodium; FasL: Fas Ligand; FGF: Fibroblast growth factor; GM-CSF: Granulocyte-macrophage colony stimulating factor; GMSC: Mesenchymal stem cell derived from gingiva; ...
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Th17-related cytokines: new players in the control of chronic intestinal inflammation
... of dextran sulfate sodium (DSS) [48]. DSS delivered with drinking water to mice causes disruption of the epithelial layer, which is followed by translocation of luminal bacteria to the ...
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PubMedCentral-PMC5319916.pdf
... (AOM)/Dextran Sulfate Sodium (DSS)-induced colon cancer model, intestine-specific Sirt1 heterozygous deletion mice (Villin-Cre + /Sirt1 flox/+ , Sirt1 iHet) developed significantly more and ...
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Original Article The effects of Qing Hua Chang Yin on the epithelial tight junctions of mice with inflammatory bowel disease
... the dextran sulfate sodium (DSS)-induced ulcerative colitis mouse ...of DSS-induced colitis was monitored daily in a blinded manner, including the observation of changes in body weight, ...
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Red Seaweed Eucheuma cottonii Ethanol Extract
... curcumin in dextran sulfate sodium (dss)-induced ulcerative colitis murine model. Defining the microbial transcriptional response to colitis[r] ...
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TSG-6 released from intraperitoneally injected canine adipose tissue-derived mesenchymal stem cells ameliorate inflammatory bowel disease by inducing M2 macrophage switch in mice
... cell; DSS: Dextran sulfate sodium; ELISA: Enzyme-linked immunosorbent assay; FITC: Fluorescein isothiocyanate; GAPDH: Glyceraldehyde 3-phosphate dehydrogenase; IACUC: Institutional Animal Care ...
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Ferrous sulfate, but not iron polymaltose complex, aggravates local and systemic inflammation and oxidative stress in dextran sodium sulfate-induced colitis in rats
... (DSS, DSS + IPC, DSS + FS), gross anatomy of the colon showed numerous areas with loss of mucosal folds and a variable degree of mucosal edema and congestion, along with submucosal hemorrhage and ...
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Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial mesenchymal transition and myeloid derived suppressor infiltration
... The epithelial-mesenchymal transition (EMT) is a process in which epithelial cells trans-differentiate and ac- quire an invasive mesenchymal phenotype. Activated nu- clear factor-κB (NF-κB), signal transducer and ...
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Expression of Blimp-1 in Dendritic Cells Modulates the Innate Inflammatory Response in Dextran Sodium Sulfate-Induced Colitis
... of DSS treatment of Blimp-1 cko mice exhib- ited highly inflamed phenotypes (Fig- ure 3B), increased weight with a shorter length of colon and an increased histol- ogy score, compared with WT mice (Fig- ure ...
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Invitro and invivo pharmacological studies using chitosan
... employs dextran sodium sulfate (DSS), a chemicalcolitogen with anticoagulant properties, to induce ...disease. DSS is a water- soluble, negatively charged sulfated polysaccharide with a ...
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Mak'Anyengo, Rachel (2017): Role of the NIrp3 inflammasome in regulation of the tolerogenic function of CD103+ dendritic cells in CD4+CD45RbHigh T cell transfer colitis and in steady state. Dissertation, LMU München: Medizinische Fakultät
... inflammasome. Dextran sodium sulphate (DSS)-induced colitis is an important model for the study of mucosal damage and innate immunity in ...up DSS, leading to activation of the Nlrp3 ...
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Comparative Study on Nigerian Wild and Edible Beans in Reversing Incidence of Colon Cancer in Albino Rats
... of Dextran Sodium Sulphate (DSS) dissolved in water for seven days to induce colonic ...the DSS-water was given to the singly caged rat under group A-E ...weight DSS treated water, ...
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In Vitro and In Vivo Evaluations of Sodium Lauryl Sulfate and Dextran Sulfate as Microbicides against Herpes Simplex and Human Immunodeficiency Viruses
... Our results also showed that DS was a potent inhibitor of the infectivity of HSV-1 and HSV-2 strains in vitro. A similar effect of DS was observed for various enveloped viruses, such as HSV, cytomegalovirus, vesicular ...
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Absence of bacterially induced RELMβ reduces injury in the dextran sodium sulfate model of colitis
... tion of colonic crypt structures containing isolated goblet cells despite the presence of an intense inflammatory infiltrate (Figure 3, D and F). The dilated crypt structures lined with isolated goblet cells suggest ...
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The Role of Lactic Acid Bacteria in the Pathophysiology and Treatment of Irritable Bowel Syndrome (IBS)
... The Role of Lactic Acid Bacteria in the Pathophysiology and Treatment of Irritable Bowel Syndrome IBS croflora but Does not Heal Chronic Dextran-Sodium Sulfate-Induced Colitis or Reinfor[r] ...
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