diagnostic biomarker
Effectiveness of urine fibronectin as a non invasive diagnostic biomarker in bladder cancer patients: a systematic review and meta analysis
... Besides, the limitations of this meta-analysis were as fol- lows. First, a not small heterogeneity was observed in this meta-analysis, especially in the Spe and DOR. Although we tried to explore the sources of the ...
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KIAA1199 as a potential diagnostic biomarker of rheumatoid arthritis related to angiogenesis
... Our previous comparative proteomic study showed that KIAA1199 was 5.19 times over-expressed in RA FLS cells as identified by automated 2D-Nano-LC-ESI- MS/MS [19]. This finding is supported by Yoshida’s re- sult showing ...
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Investigation of HNF-1B as a diagnostic biomarker for pancreatic ductal adenocarcinoma
... useful diagnostic biomarker for tumors of the pancreaticobiliary origin with high sensitivity and negative predictive value, but moderate specificity and accuracy for these ...
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Proteoglycan 4 is a diagnostic biomarker for COPD
... Objective: The objective of this study is to discover a diagnostic biomarker for COPD. Methods: Sixty-one subjects with COPD and 15 healthy controls (10 healthy non-smokers and 5 smokers) were recruited for ...
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Original Article Drebrin is a potential diagnostic biomarker for breast cancer
... Abstract: Breast cancer (BC) is the leading cause of death among solid tumors in women. Although new therapeutic agents have been developed since few decades ago, many patients still died of the disease due to relapse. ...
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Original Article MicroRNA301 is a potential diagnostic biomarker for hepatocellular cancer
... Abstract: We explored microRNA301 diagnosis value in hepatocellular cancer (HCC), attempting to provide novel insights for early detection, effective prevention, and timely treatment. 42 patients with HCC and 38 controls ...
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Chromogranin A is a reliable serum diagnostic biomarker for pancreatic neuroendocrine tumors but not for insulinomas
... Results: Serum levels of CgA in 89 PNET patients were significantly higher than that in healthy controls (P = 7.2 × 10 −9 ). Serum levels of CgA in 57 patients with insulinomas (median 64.8 ng/ml, range 25 – 164) were ...
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ProNGF is a potential diagnostic biomarker for thyroid cancer
... cancer biomarker has been found with sufficient sensitivity and specificity ...the diagnostic performance of proNGF in comparison and combination with the currently used ...
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Prospects for developing an accurate diagnostic biomarker panel for low prevalence cancers
... different biomarker subsets would increase the overall number of biomarkers necessary in the ...different biomarker set might alter the number of total biomarkers required to achieve high ...filtering ...
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Identification of an early diagnostic biomarker of lung adenocarcinoma based on co expression similarity and construction of a diagnostic model
... with diagnostic efficacy from these genes, we screened them through machine learning ...with diagnostic efficacy and used these genes as features to construct a diagnostic ...model’s ...
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Clinical utility of microRNA-378 as early diagnostic biomarker of human cancers: a meta-analysis of diagnostic test
... necessary to make decisions combined with miRNAs. because it is reported that the combination of miRNA-371 with other miRNAs generate a more accurate result [18]. Second, there are seven types of cancer in the meta- ...
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miRNA-1, miRNA-145 As A Myocardial Infarction Diagnostic Biomarker
... Rapid and correct diagnosis is crucial to treatment and prognosis of AMI. Up to date, cardiac troponins and creatine kinase-MB are the most commonly used biomarkers for AMI, but their clinical value is limited in many ...
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Is APC hypermethylation a diagnostic biomarker for bladder cancer? A meta-analysis
... area under the curve (AUC) value of APC hypermethylation for bladder cancer were calculated. Results: In total, 14 articles with 531 controls and 1,293 cases were included to assess the associations of APC promoter ...
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Estimating the optimal threshold for a diagnostic biomarker in case of complex biomarker distributions
... The present article is an application of a previously published Bayesian method to estimate the optimal threshold of a biomarker to two distributions among the most able to take into account heterogeneity in ...
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miR-17 as a diagnostic biomarker regulates cell proliferation in breast cancer
... The expression of miR-17 was significantly increased in prostate cancer, 25,32 gastric cancer, 33–35 and colon cancer cells, 36–38 which suggests a potential tumor promoter function [r] ...
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Original Article Evaluation of CK-MB as a diagnostic biomarker in acute appendicitis
... priate diagnostic approach. In a study evaluat- ing diagnostic value of MPV, PMV was identified as an important marker when evaluated prior to surgery ...no diagnostic value for ...
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Preliminary characterizations of a serum biomarker for sarcoidosis by comparative proteomic approach with tandem-mass spectrometry in ethnic Han Chinese patients
... a diagnostic biomarker of Chinese sarcoidosis compared with non-sarcoidosis groups that include healthy controls and patients with tuberculosis, interstitial lung diseases and lung ...
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<p>hsa_circRNA_101237: A Novel Diagnostic and Prognostic Biomarker and Potential Therapeutic Target for Multiple Myeloma</p>
... Circular RNA (circRNA), an emerging class of non- coding RNA, has a covalently closed loop structure in which the 3 ′ and 5 ′ ends are linked in a non-collinear way by a process termed “ back-splicing ” . 8 After its fi ...
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Serum miR-26a as a diagnostic and prognostic biomarker in cholangiocarcinoma
... non-invasively diagnostic biomarker and prognostic factor is that we used to speculate miRNAs could not keep intact in serum, as tremendous RNases are existed in circulation [38, ...valuable ...
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Original Article MiR-675 is over-expressed in patients with prostate cancer
... ising biomarker used for more accurate diagno- sis in prostate cancer combination with ...valuable diagnostic biomarker combination with PSA in prostate cancer ...
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