differentially methylated regions
De novo identification of differentially methylated regions in the human genome
... of differentially methylated regions (DMRs) between phenotypes in the human genome is of prime interest in ...most differentially methylated regions across the genome based on ...
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De novo identification of differentially methylated regions in the human genome
... of differentially methylated regions (DMRs) between phenotypes in the human genome is of prime interest in ...most differentially methylated regions across the genome based on ...
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BSmooth: from whole genome bisulfite sequencing reads to differentially methylated regions
... of differentially methylated regions To find regions exhibiting consistent differences between groups of samples, taking biological variation into account, we compute a signal-to-noise ...
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Comprehensive methylation analysis of imprinting-associated differentially methylated regions in colorectal cancer
... chromosomal regions called imprinting ...imprinting-associated differentially methylated regions (iDMRs) within these domains [1, ...maternally methylated and paternally ...
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methylCC: technology independent estimation of cell type composition using differentially methylated regions
... Bump hunting to identify differentially methylated regions in epigenetic epidemiology studies. Int J Epidemiol. 2012;41(1):200–9. https://doi.org/ 10.1093/ije/dyr238. 27. Huber W, Carey VJ, Gentleman ...
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Major chromosomal breakpoint intervals in breast cancer co-localize with differentially methylated regions
... breakpoint regions with differentially methylated regions (DMR), coupled with additional genomic parameters, such as repeat elements and designated “fragile sites” in the reference ...
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Genetic and epigenetic variation among inbred mouse littermates: identification of inter-individual differentially methylated regions
... Results: Using whole genome bisulphite sequencing of DNA from the livers of five mice from the A vy colony, we searched for sites at which DNA methylation differed among the mice. A small number of loci, 356, were ...
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Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies
... with differentially methylated regions (DMRs) whereby one of the two alleles is DNA methylated depending on the parent of ...regulatory regions associated with a particular gene, only ...
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Inter-individual methylation variability in differentially methylated regions between maternal whole blood and first trimester CVS
... of differentially methylated regions (DMRs) on chromosomes 18 and ...all regions tested, enrichment was higher in CVS than in WBF samples with mean enrichments ranging from ...
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Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population
... Abstract Age-related changes in DNA methylation have been implicated in cellular senescence and longevity, yet the causes and functional consequences of these variants remain unclear. To elucidate the role of age-related ...
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Differentially methylated regions in T cells identify kidney transplant patients at risk for de novo skin cancer
... In this retrospective study, we aimed to identify kidney transplant patients at risk for de novo post-transplant cSCC by studying genome-wide DNA methylation of T cells. We analyzed samples collected before transplant- ...
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DMRcaller: a versatile R/Bioconductor package for detection and visualization of differentially methylated regions in CpG and non-CpG contexts
... In particular, we introduce DMRcaller , a highly ef- ficient R/Bioconductor package, which implements several methods to detect differentially methylated regions (DMRs) between two samples. Most ...
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Dynamic stage specific changes in imprinted differentially methylated regions during early mammalian development and prevalence of non CpG methylation in oocytes
... with differentially methylated regions (DMRs) that are CpG methylated on one of the two parental ...corresponding regions in sperm and ...maternally methylated DMRs as well as ...
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Detection of differentially methylated regions of irradiated fig tree selections
... polymorphic regions, analyzable by bioin- formatic ...the differentially methylated sites, makes it possible to observe different patterns of methylation by sequencing the treated DNA with sodium ...
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Prediction of gestational age based on genome wide differentially methylated regions
... have differentially methylated CpGs in our study, CpGs associated with these genes were not used in either the ultrasound- or LMP-based GA prediction ...
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Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array
... promoter regions and CpG islands, and also covers other potentially relevant features, including downstream genic and intergenic ...in regions outside CGIs or CGI flanking ...CpG-poor regions near ...
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Detecting multiple differentially methylated CpG sites and regions related to dimensional psychopathology in youths
... entially methylated region of a gene involved in neurogenesis ...ferentially methylated and differentially expressed gene located at the MHC region (HLA-E), which is the most robustly associated ...
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Novel parent-of-origin-specific differentially methylated loci on chromosome 16
... 22 differentially methylated regions (DMRs) with ≥ 5 consecutive CpG methylation sites and varying tissue-specificity, including the known DMRs associated with the established imprinted gene ZNF597 ...
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Detecting differentially methylated loci for Illumina Array methylation data based on human ovarian cancer data
... 2. Rakyan VK, Down TA, Thorne NP, Flicek P, Kulesha E, Gräf S, Tomazou EM, Bäckdahl L, Johnson N, Herberth M: An integrated resource for genome- wide identification and analysis of human tissue-specific ...
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Epigenetic signature of differentially methylated genes in cutaneous melanoma
... Additional file 2: Table S1. Number of differentially methylated genes in the comparison of cutaneous melanomas carrying distinct driver mutations with the group of control melanocytes. Δ M refers to the ...
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