Differentiation with retinoic acid
Retinoic acid regulates olfactory progenitor cell fate and differentiation
... of retinoic acid signaling in the induction of the olfactory epithelium, the generation and maintenance of progenitor populations, and the ontogenesis and differentiation of olfactory ...
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Ethanol (Etoh)-Mediated Differentiation Of Embryonic Stem Cells Via Retinoic Acid (Ra)-Retinoic Acid Receptor-Gamma (Rar?) Signaling
... all-trans-retinoic acid (RA), which plays a critical role in differentiation and ...on differentiation, we show that mRNAs associated with differentiation are increased by EtOH and its ...
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PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology
... In this work, we explored the mechanistic and functional role of PRMT1 and PRMT8 using a multistage differentiation model of mouse embryonic stem cells (ESCs) to neurons. Our findings implicate asymmetric arginine ...
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PRMT1 and PRMT8 regulate retinoic acid-dependent neuronal differentiation with implications to neuropathology
... In this work, we explored the mechanistic and functional role of PRMT1 and PRMT8 using a multistage differentiation model of mouse embryonic stem cells (ESCs) to neurons. Our findings implicate asymmetric arginine ...
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Retinoic acid is both necessary for and inhibits myogenic commitment and differentiation in the chick limb
... ABSTRACT Retinoic acid (RA) plays an essential role in the development of many embryonic tissues, including the developing tetrapod limb ...Myogenic differentiation is initiated by expression of Myf5 ...
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Induction of thrombospondin 1 by retinoic acid is important during differentiation of neuroblastoma cells
... neuronal differentiation in the treatment of this malignancy. Retinoic acid is one agent in particular that has been shown to induce growth inhibition and terminal differentiation of ...
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Polyomavirus Small t Antigen Prevents Retinoic Acid-Induced Retinoblastoma Protein Hypophosphorylation and Redirects Retinoic Acid-Induced G0 Arrest and Differentiation to Apoptosis
... of retinoic acid (RA)-induced HL-60 myeloid differentiation as well as growth arrest, causing apoptosis ...surface differentiation marker, but inducible oxidative metabo- lism, a later and ...
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Retinoic acid can change normal differentiation of rat egg cylinders cultured in vitro
... Int J DeL BioI 35 197 202 (1991) 197 Retinoic acid can change normal differentiation of rat egg cylinders cultured in vitro VESNA CRNEK MAJA VLAHOVIC and NIKOLA SKRES* Institute of Biology, Faculty of[.] ...
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CaMKII regulates retinoic acid receptor transcriptional activity and the differentiation of myeloid leukemia cells
... USA. Retinoic acid receptors (RARs) are members of the nuclear hormone receptor family and regulate the pro- liferation and differentiation of multiple different cell types, including promyelocytic ...
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Retinoic acid enhances germ cell differentiation of mouse skin-derived stem cells
... Background: Retinoic acid (RA) signaling has been identified as a key driver in male and female gamete ...cell differentiation to germ cells, particularly on the initiation of ...
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Retinoic acid orchestrates fibroblast growth factor signalling to drive embryonic stem cell differentiation
... cell differentiation. Retinoic acid also induces differentiation in many cellular contexts, but its mechanism of action in relation to Fgf/Erk signalling in ES cells is poorly ...to ...
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Retinoic Acid Regulates Differentiation of the Secondary Heart Field and TGFβ-Mediated Outflow Tract Septation
... the differentiation of the second heart field (SHF) and heart outflow tract septation defects are combined, although the mechanistic basis for this relationship has been ...In retinoic acid (RA) ...
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Retinoic acid receptor signaling preserves tendon stem cell characteristics and prevents spontaneous differentiation in vitro
... identified retinoic acid receptor (RAR) agonists as potent inducers of nuclear Scx in the small molecule ...spontaneous differentiation rather than the anticipated induction of tenogenic ...
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Targeting the scaffolding role of LSD1 (KDM1A) poises acute myeloid leukemia cells for retinoic acid-induced differentiation
... of retinoic acid (RA) induce differentiation of APL cells, triggering degradation of the PML-RAR ...block differentiation, while RA with targeting of LSD1 releases a differentiation ...
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Midkine (MK), the product of a retinoic acid responsive gene, and pleiotrophin constitute a new protein family regulating growth and differentiation
... Inl I De, lIilll '1 183 188 (1~~3) 183 Midkine (MK), the product of a retinoic acid responsive gene, and pleiotrophin constitute a new protein family regulating growth and differentiation TAKASHI MURA[.] ...
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Retinoid activation of retinoic acid receptors but not of retinoid X receptors promotes cellular differentiation and replication of human cytomegalovirus in embryonal cells.
... on retinoic acid (RA) ...to retinoic acid involve two distinct subfamilies of nuclear receptors, the RA receptors (RARs) and retinoid X receptors (RXRs), which function by activating ...
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Retinoic acid improve germ cell differentiation from human embryonic stem cells
... hESCs differentiation into EBs, expression of the early gonocyte specific marker VASA was initiated together with expression of SCP3, GDF9 and ...hESCs differentiation in ...
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Interactions between FGF18 and retinoic acid regulate differentiation of chick embryo limb myoblasts
... development is also delayed but not abrogated (Liu et al., 2007) suggesting that the regulation of timing of differentiation may be a conserved feature of FGF18 function although muscle defects in this mouse have ...
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Retinoic acid induces HL-60 cell differentiation via the upregulation of miR-663
... Thousands of miR-663 target genes have been pre- dicted by bioinformatic analysis and interestingly, most are transcription factors of AP-1 [28]. In THP-1 cells, miR-663 decreases endogenous activator protein-1 (AP- 1) ...
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Effect of all-trans retinoic acid on the proliferation and differentiation of brain tumor stem cells
... induce differentiation through GFAP gene ...the differentiation of BTSCs from the level of molecular ...the differentiation of BTSCs into more mature ones, and prevents the differentiated BTSCs from ...
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