Diffuse-type gastric cancer
Prognostic factors in patients with diffuse type gastric cancer (linitis plastica) after operative treatment
... the diffuse type gastric cancer is characterized by infiltration of neoplastic cells with significant desmo- plastic response, imparting a rigid, fibrotic appearance to the wall ...
5
Original Article Down-regulated expression of Rap1GAP predicts unfavorable prognosis in diffuse type gastric cancer and may be correlated with EMT
... with gastric cancer. Methods: A total of 219 patients with gastric cancer who were underwent surgery were enrolled in this ...of diffuse type gastric cancer and in ...
11
A subset of diffuse-type gastric cancer is susceptible to mTOR inhibitors and checkpoint inhibitors
... and diffuse-type GC tissues ...that diffuse-type GC patients with strong p-mTOR expression had a significantly worse prognosis than those with weak p-mTOR expression ( n = 227; P = ...
23
Notch1 directly induced CD133 expression in human diffuse type gastric cancers
... including gastric cancers, and Notch1 signaling is known to play an important role in the maintenance and differentiation of stem-like ...of gastric cancers and CD133 ...of diffuse type ...
10
Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer
... mixed type, and as well, a trend toward a negative correlation between HES1 and HATH1 was found in the diffuse and mixed ...in gastric cancer compared to normal mucosa has been reported ...
11
Low frequency of E cadherinalterations in familial breast cancer
... breast cancer Thus far, E-cadherin germline mutations have been reported in 17 diffuse gastric cancer families ...by gastric cancer, and the age of onset of at least one case was ...
9
Genomic profile analysis of diffuse type gastric cancers
... of diffuse-type gastric cancer, using matched tumor and normal samples from 14 diffuse-type and five intestinal-type gastric cancer ...the ...
15
Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma
... Gastric cancer (GC) is one of the most prevalent cancer types ...subtypes, diffuse-type GC and intestinal-type GC, according to the Laurén classification ...the ...
17
Non-Destructive Determination of Magnetic Audio Tape Degradation for Various Tape Chemistries Using Spectroscopy and Chemometrics
... of gastric adenocarcinomas can be classified into one of two categories: intestinal-type or ...intestinal-type gastric cancers are on the decline, while diffuse-type are on the ...
67
A short guide to hereditary diffuse gastric cancer
... stomach cancer, the intestinal and the diffuse type (DGC) ...with diffuse-type gastric adenocarcinoma but not with other types of stomach cancer in the absence of a ...
12
<p>CDH1 (E-Cadherin) Mutation and Gastric Cancer: Genetics, Molecular Mechanisms and Guidelines for Management</p>
... The Rho family of GTPases belongs to the RAS super- family. They act as binary molecular switches and regulate many aspects of intracellular cytoskeleton dynamics, moti- lity and cell polarity, cell proliferation. ...
10
A novel diffuse gastric cancer susceptibility variant in E-cadherin (CDH1) intron 2: A case control study in an Italian population
... the gastric mucosal surface [3], DGC is usually diagnosed at an advanced stage and consequently associated with a poorer outcome ...intestinal type on the basis of its abnormal expression of the cell-cell ...
10
Case Report Epithelioid malignant mesothelioma presenting with features of gastric tumor in a child
... and gastric stromal ...of gastric cancer and gastric stromal ...of diffuse malignant epithelioid mesothelioma, so the diagnosis of primary localized malignant mesothelioma, epithelial ...
5
Familial gastric cancer: detection of a hereditary cause helps to understand its etiology
... both diffuse and intes- tinal type GC has been shown in several well known hereditary cancer syndromes, besides ...ovarian cancer [27,28], familial aden- omatous polyposis (FAP) [29-31], ...
6
Different clinical significance of FGFR1–4 expression between diffuse type and intestinal type gastric cancer
... lung cancer [19] and colorectal cancer ...Colorectal cancer cell lines cocultured with tumor-associated fibroblasts (TAF) induced signifi- cant overexpression of FGFR4, but not of other FGFRs ...
9
The Morphological Features of “Cavitary” Type Angiogenesis in Diffuse and Intestinal Types of Gastric Cancer and Its Relationship with Tumor-Infiltrating Immune Cells
... second type of CS formation (CS type-2) was associated with the formation of CS directly into the GM or the tumor stroma, without involvement of the tumor ...of gastric pits or directly in the stroma ...
13
Original Article GSTP1 exon 5 rs200139798 polymorphism and clinicopathological characteristics of gastric cancer in Chinese patients
... in gastric cancer in relation to histological ...216 gastric cancers and 300 benign gastric diseases as ...and gastric cancer was observed in subjects carrying at least one G ...
6
Breast Cancer in Western Iraq: Clinicopathological Single Institution Study
... breast cancer is suspected, BRCA1, BRCA2, TP53 and ...for gastric cancer of the diffuse type, but the excess of breast cancers of the lobular type in CDH1families led researchers ...
7
Using fruitflies to help understand the molecular mechanisms of human hereditary diffuse gastric cancer
... Two other observations were of interest: if hEcad is driven in cells ubiquitously expressing GFP-tagged DEcad, the amounts of GFP-DEcad decrease, indicating that DEcad is subject to a posttranslational downregulation ...
5
Prophylactic gastrectomy in familial gastric cancer: case report and review of literature
... the diffuse histo- logical type, frequently resulting in linitis plas- tic, as a result, mucosal abnormalities tend to occur late and delay the endoscopic ...of gastric cancer cases are ...
6