dipeptidyl peptidase IV
Dipeptidyl Peptidase IV (DPP-IV) Inhibitory Activity of Metformin
... Dipeptidyl peptidase IV is plasma membrane glycoprotein exopeptidase, inhibition of DPP-IV activity could be a useful strategy to enhance the activity of ...DPP- IV levels and lipid ...
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RELATIONSHIP OF SERUM DIPEPTIDYL PEPTIDASE IV ACTIVITY AND ANTI CASEIN ANTIBODIES TO GASTROINTESTINAL SYMPTOMS AMONG CHILDREN WITH AUTISM SPECTRUM DISORDER: AN EGYPTIAN STUDY
... Dipeptidyl peptidase-IV (DPP-IV) (CD26), a proteolytic protein- digesting enzyme, has been contained within the cells lining the small intestine ...
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Optimization of gold nanoparticle based real time colorimetric assay of dipeptidyl peptidase IV activity
... Dipeptidyl peptidase IV (DPP-IV also referred to as CD-26) is a serine protease enzyme with remarkable diagnostic and prognostic value in a variety of health and disease ...
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Intraindividual changes of dipeptidyl peptidase IV in peripheral blood of patients with rheumatoid arthritis are associated with the disease activity
... Dipeptidyl peptidase-IV (DPP-IV, CD26, EC ...membrane peptidase that selectively cleaves an N- terminal dipeptide from peptides with a proline or alanine residue in the penultimate ...
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Dipeptidyl peptidase IV reduces trophoblast invasion by inhibiting the activity of MMPs
... ABSTRACT Preeclampsia is a severe pregnancy complication in part due to insufficient implanta- tion. This study aimed at elucidating the mechanism of action of dipeptidyl peptidase IV (DPPIV) in ...
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Inhibition of dipeptidyl peptidase IV enzyme activity protects against myocardial ischemia reperfusion injury in rats
... Figure 4 Immunohistochemical (IHC) stains of inflammatory cell infiltrations in LV myocardium at 72 h after IR procedure. A to E) Microscopic findings (400×) of IHC staining for identifying CD14+ cells (brown color) ...
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CD26/dipeptidyl peptidase IV (CD26/DPPIV) is highly expressed in peripheral blood of HIV 1 exposed uninfected Female sex workers
... A recent preliminary gene expression analysis of HIV resistant female sex workers who had been in active sex work for periods of more than seven years and remained HIV uninfected suggested a high expression of CD26/ ...
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Interaction of human dipeptidyl peptidase IV and human immunodeficiency virus type 1 transcription transactivator in Sf9 cells
... RESEARCH Open Access Interaction of human dipeptidyl peptidase IV and human immunodeficiency virus type 1 transcription transactivator in Sf9 cells Felista L Tansi1, V?ronique Blanchard2, Markus Berge[.] ...
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Placental extracellular vesicles express active dipeptidyl peptidase IV ; levels are increased in gestational diabetes mellitus
... GDM. Dipeptidyl peptidase IV (DPPIV) is known to play a role in type 2 diabetes by breaking down GLP-1, which in turn regulates glucose-dependent insulin ...
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Dipeptidyl peptidase IV, aminopeptidase N and DPIV/APN-like proteases in cerebral ischemia
... degeneration. Dipeptidyl peptidase IV, aminopeptidase N as well as the dipeptidyl peptidases II, 8 and 9 and cytosolic alanyl-aminopeptidase are involved in the regulation of autoimmunity and ...
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Synthesis and characterization of oxidovanadium complexes as enzyme inhibitors targeting dipeptidyl peptidase IV
... hyperlipidemia. Dipeptidyl peptidase IV (DPP-IV) inhibitors are a new type of oral hypoglycemic agents for the treatment of patients with type 2 diabetes ...
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Estimation of Dipeptidyl Peptidase IV in Oral Squamous Cell Carcinoma Patients undergoing Radiotherapy
... Particularly, the serine proteases (SP) comprise the best characterized family of proteases due to exhaustive studies conducted in the last 50 years with kinetic, chemical, physical and genetic techniques. A remarkable ...
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Ligand Based in-silico Study on Pyridopyrimidinedione Derivatives as Dipeptidyl Peptidase-IV Inhibitors
... Background: Type-2 diabetes mellitus can be effectively treated with dipeptidyl peptidase- IV inhibitors. Diverse classes of molecules have exhibited promising DPP-IV inhibition. Objective: In ...
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Natural dipeptidyl peptidase-IV inhibitor mangiferin mitigates diabetes- and metabolic syndrome-induced changes in experimental rats
... Results: The treatment with MNG showed beneficial effects on various components of metabolic syndrome, such as reduced dyslipidemia (decreased triglyceride, total cholesterol, low-density lipoprotein cholesterol, and ...
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Study of the stability of functionalized gold nanoparticles for the colorimetric detection of dipeptidyl peptidase IV
... Abstract: In this report, we investigated three stabilization strategies of gold nanoparticles and their practical application for the visual detection of dipeptidyl peptidase IV (DPP-IV). ...
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Glucagon-like peptide-1 (GLP-1) mediates the protective effects of dipeptidyl peptidase IV inhibition on pulmonary hypertension
... DPP-4: Dipeptidyl peptidase IV; EndMT: Endothelial-mesenchymal transition; GLP-1: Glucagon-like peptide-1; H&E: Hematoxylin and eosin; HUVECs: Human umbilical vein endothelial cells;[r] ...
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Dipeptidyl Peptidase-IV Inhibitors: Pharmacological Profile and Clinical Use
... MH, Huaibing H, Hickey G, Kowalchick JE, Leiting B, Lyons K, Marsilio F, Mccann ME, Patel R, Petrov A, Scapin G, Patel S, Ranabir A, Singa R, Wu J, Wyvratt MJ, Zhang BB, Zhu L, Thornberry NA, Weber AE: ...
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Streptokinase Promotes Development of Dipeptidyl Peptidase IV (CD26) Autoantibodies after Fibrinolytic Therapy in Myocardial Infarction Patients
... Dipeptidyl peptidase IV (DPP IV) (CD26) plays a critical role in the modulation and expression of auto- immune and inflammatory ...DPP IV and high titers of anti-DPP IV autoanti- ...
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Inhibition of dipeptidyl peptidase IV by fexofenadine: Virtual screening study
... Dipeptidyl peptidase IV (DPP IV) is relatively new anti-diabetic ...DPP IV inhibitors lower fasting and postprandial glucose concentrations by preventing the degradation of the natural ...
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Distribution of Dipeptidyl Peptidase IV in Patients with Chronic Tonsillitis
... involved. Dipeptidyl peptidase IV (DPP IV) and aminopeptidase N (APN) participate in the regulation of the immune response during ...DPP IV and the enzymatic activities of DPP IV ...
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