Direct- acting antivirals:
Therapeutic monitoring of direct-acting antivirals for the treatment of hepatitis C
... Abstract Background. Chronic hepatitis C virus (HCV) infection affects about 71 million people worldwide. Nowadays, the standard therapy of chronic HCV infection is based on direct-acting antivirals ...
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Drug–Drug Interactions Between Direct-Acting Antivirals and Psychoactive Medications
... Published online: 17 June 2016 Ó The Author(s) 2016. This article is published with open access at Springerlink.com Abstract Treatment options for chronic hepatitis C virus (HCV) infection have drastically changed since ...
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Effectiveness of Treatment of Chronic Viral Hepatitis C by Direct Acting Antivirals in Togo
... of direct acting antivirals has revolutionized the care and prognosis of patients infected with hepatitis C virus ...with direct-acting antivirals were ...
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Managing HIV/hepatitis C co-infection in the era of direct acting antivirals
... the direct fibrogenetic ef- fect of HIV in the liver and a likely consequence of HIV induced impairment of the innate and adaptive immune system leading to more inflammation, apoptosis and fi- brosis ...of ...
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Hepatitis C Virus and Hepatocellular Carcinoma: Pathogenetic Mechanisms and Impact of Direct-Acting Antivirals
... following DAA treatment is not only to eradicate the virus, but to improve liver function too, such as cirrhosis, fibrosis and HCC. In particular, the reduction of inflammation can lead to a decrease of cirrhosis and ...
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REDUCTION OF SPLENIC VOLUME AFTER DIRECT ACTING ANTIVIRALS TREATMENT IN PATIENTS WITH HCV COMPENSATED CIRRHOSIS
... of direct-acting antivirals (DAAs) treatment on spleen size and portal circulation after the achievement of sustained virological response (SVR) in patients with hepatitis C virus (HCV)-related ...
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Direct-Acting Antivirals (DAAs): Drug-Drug Interactions (DDIs) in the Treatment of Hepatitis C Virus (HCV)
... Sabina Steiner, Nikola Raguž-Lučić and Damir Erceg Additional information is available at the end of the chapter Abstract Hepatitis C virus (HCV)-infected patients often use multiple medications to treat infection, ...
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Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepatitis C
... DISCUSSION There is an unmet medical need for novel strategies for the pre- vention of HCV graft infection following LT, and a need to develop more ef ficient and better tolerated combination therap- ies for chronic ...
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The Effect of Direct Acting Antivirals on Portal Hemodynamics in Patients with Post Hepatitis C Cirrhosis: Doppler Study
... receiving direct acting drugs had been established that results in reduced morbidity and mortality due to chronic liver disease, however how this affects clinical outcomes in patients with already ...
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Impact of hepatitis C virus genotype-4 eradication following direct acting antivirals on liver stiffness measurement
... impact of hepatitis c virus genotype-4 eradication following direct acting antivirals on liver stiffness measurement.. Mohammed Tag-adeen 1,2.[r] ...
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Hepatitis C virus cell entry: a target for novel antiviral strategies to address limitations of direct acting antivirals
... Hepatitis C virus cell entry: A target for novel antiviral strategies to address limitations of direct acting antivirals Che C. Colpitts 1,2 and Thomas F. Baumert 1,2,3 1 Inserm, U1110, Institut de ...
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The Australasian Hepatology Association consensus guidelines for the provision of adherence support to patients with hepatitis C on direct acting antivirals
... subsidizing direct acting antivirals (DAAs) for the treatment of hepatitis C, which are highly effective (95% cure rate) and have few side ...
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Predictors of Direct Acting Antivirals Failure in Patients with Chronic Hepatitis C Virus in Ivory Coast: About 5 Cases
... DOI: 10.4236/ojgas.2019.910022 195 Open Journal of Gastroenterology linical profile of patients who have failed treatment with the hepatitis C virus. 2. Patients and Methodology It was a cross-sectional and descriptive ...
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Incidence and risk factors of early HCC occurrence in HCV patients treated with direct acting antivirals: a prospective multicentre study
... Methods: According to the Italian ministerial guidelines for direct-acting-antivirals treatment, 1022 consecutive HCV patients treated with direct-acting-antivirals were ...
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Predictors of Hepatitis C Treatment Failure After Using Direct-Acting Antivirals in People Living With Human Immunodeficiency Virus.
... First, a documented PHQ-9 score of 9 or higher indicative of ongoing depression symptoms within 3 months of starting DAA treatment. Second, if patients had a mental illness different than depression according to ...
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Budget impact and cost-effectiveness analyses of direct-acting antivirals for chronic hepatitis C virus infection in Hong Kong
... The purpose of this investigation was to evaluate the budget impact and cost-effectiveness of direct-acting antivirals (DAAs) for the treatment of hepatitis C virus (HCV) infection in Hong Kong. A ...
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A case series evaluating the impact of Hepatitis C eradication using direct acting antivirals on primary biliary cholangitis-associated autoimmunity
... Although not common, patients with primary biliary cholangitis (PBC) and concurrent HCV infection (PBC-HCV) have been previously described [8, 9]. PBC-HCV patients appear to have more aggressive liver disease, as ...
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Ribavirin Concentrations, Laboratory Variables, and Clinical Outcomes During Treatment of Hepatitis C Infection with First Generation Direct-Acting Antivirals
... Email address: To cite this article: Halina Michur, Phillip Morgan, Ivana Carey, Nigel Brown, Nigel Heaton, Michael Heneghan, Kosh Agarwal, John Michael Tredger. Ribavirin Concentrations, Laboratory Variables, and ...
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New Research On Direct-acting Antivirals For The Treatment Of Hepatitis C
... To determine if the combination of sofosbuvir/ledipasvir (SOF/LDV) is effective in treatment-naïve, genotype-1, HCV-infected patients, to determine whether 12 weeks of treatment is suff[r] ...
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Emerging Direct-Acting Antivirals for Treatment of Chronic Hepatitis C
... 15 DAA Classes NS3/4A PIs NS5B Polymerase Inhibitors NS5A Inhibitors Nucleoside /tide Non-nuc (multiple subclasses) Genotypic Coverage Limited* Pan- genotypic Limited Va[r] ...
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