Disease susceptibility
Modern approaches to understanding stress and disease susceptibility: A review with special emphasis on respiratory disease
... and susceptibility with emphasis on respiratory ...natural disease outcomes may be more ...augments disease susceptibil- ...a disease but can also enhance disease ...predict ...
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Tree vigour influences disease susceptibility of 'Hass' avocado fruits
... influence disease susceptibility, fruit ripening rates and fruit size of ‘Hass’ ...increased disease resistance of fruits from non-vigorous trees was related to a 40% increase in the concentration of ...
5
The genetics of infectious disease susceptibility: has the evidence for epistasis been overestimated?
... In support of such genetic models, studies of infectious disease susceptibility have commonly documented three key indicators of epistasis. Both linkage and association mapping studies have shown that ...
5
Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci
... on disease susceptibility and assessed the predictive power of these SNPs present on the ...more disease-associated markers to be found amongst these non- GWS ...
7
The importance of the polymorphisms of the ABCB1 gene in disease susceptibility, behavior and response to treatment in inflammatory bowel disease: A literature review
... Crohn’s disease (CD) and ulcerative colitis (UD) are the 2 common clinical subtypes of idiopathic inflammatory bowel disease (IBD) characterized by chronic inflammation of the gastrointestinal ...in ...
5
Epigenetics: Impacts on Disease Susceptibility and Pharmacotherapy
... Deoxyribonucleic acid (DNA) is a hereditary material comprising of all the genetic information in humans and almost all other living creatures. It is made up of subunits called genes, which have four nucleotides. ...
12
Haplotype diversity at the CYP2D6 locus: Human demography, evolution and disease susceptibility
... Polym orphism in debrisoquine/sparteine oxidation is arguably the m ost highly studied pharmacogenetic trait. The DNA sequence encoding the enzyme has been localised to the 4.3 kb, nine-exon cytochrome P450 2D6 (CYP2D6) ...
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New methods for finding disease-susceptibility genes: impact and potential.
... the disease or phenotype under ...in disease susceptibility and to prioritize these for analyses seeking evidence of disease-associated ...significant susceptibility effects are only ...
8
Effects of Cercospora leaf spot disease on sugar beet genotypes with contrasting disease susceptibility
... sugar beet for approximately 25% and sugar cane (Saccharum officinarum L.) for about 75%. Chemical application to plants can result in the rapid development of pathogen resistance. Previously, extensive application of ...
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Mitochondrial DNA variation and disease susceptibility in primary open angle glaucoma
... on disease risk. Importantly, as POAG is a heterogeneous disease grouping, the role of mtDNA variation in patients stratified by normal-tension glaucoma, slightly elevated IOP, high IOP, progression rates, ...
5
Isolation of Arabidopsis Mutants With Enhanced Disease Susceptibility by Direct Screening
... These results show that some genes involved in SAR are also involved in limiting pathogen growth in the abscence of SAR, suggesting that a screen for enhanced diseas[r] ...
10
The X chromosome and sex-specific effects in infectious disease susceptibility
... In most countries, the TB notification rate is twice as high in HIV-negative males than in HIV-negative fe- males [80]. This ratio ranged from 1.56 to 2.73 and while it differs between countries, it was clear that more ...
12
ABCG2 polymorphisms in gout: insights into disease susceptibility and treatment approaches
... Abstract: As a result of the association of a common polymorphism (rs2231142, Q141K) in the ATP-binding cassette G2 (ABCG2) transporter with serum urate concentration in a genome-wide association study, it was revealed ...
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Common NFKBIL2 polymorphisms and susceptibility to pneumococcal disease: a genetic association study
... with disease susceptibility across different populations is perhaps of even more value than the identification of population-specific effects ...the disease associa- tion within this region, although ...
10
Genetic Background May Confer Susceptibility to PTC in Benign Multinodular Thyroid Disease
... Considering the overlap between the MNG and HN + PTC groups in unsupervised clustering approaches (data not shown) and the limited set of genes that showed high differential expression (i.e. more than 2-fold), another ...
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Utility of susceptibility weighted imaging in Parkinson’s disease and atypical Parkinsonian disorders
... with disease severity ...magnetic susceptibility of tissues where it deposits. Susceptibility-weighted imaging (SWI), a novel MRI technique, is sensitive to magnetic susceptibility of tissue, ...
8
Quantitative Susceptibility Mapping Suggests Altered Brain Iron in Premanifest Huntington Disease
... magnetic susceptibility calculated by using QSM is expected to be affected by scanning parameters to a small extent as long as the same TE range is ...calculated susceptibility values caused by the 2 ...
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“Brush Sign” on Susceptibility Weighted MR Imaging Indicates the Severity of Moyamoya Disease
... All patients underwent intra-arterial angiography to confirm Suzuki’s staging of MMD, to evaluate collateral supplies to the affected area and development of the STA as a donor vessel for direct bypass sur- gery. Brain ...
6
Keeping Pace with the Red Queen: Identifying the Genetic Basis of Susceptibility to Infectious Disease
... infectious disease, and are widely ...infectious disease, how- ever, a potentially more important problem ...infectious disease itself (Newport and Finan ...infectious disease becomes acute ...
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Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
... PNPLA3 rs738409 and evidence of hepatic inflammation, as indicated by release of liver enzymes into the circulation, and found a sig- nificant elevation in serum concentrations of alanine aminotransferase (ALT) in ...
5