Disruption, The
Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the generalized singular value decomposition
... the disruption of glycine, ser- ine and threonine metabolism may suggest that glycine and serine activity as co-agonists at the NMDA recep- tors may be disrupted in the PFC of PCP-treated ani- ...
20
The Presbyteries of Cupar, Dundee and St Andrews during the ten years conflict and disruption
... Ministers were generally able to rent accommodation reasonably near to their congregations. Not all were able to do so however. Robert Walker of Longforgan Free Church, vrho was aged 63 at the Disruption, had to ...
336
Disruption of clathrin dependent trafficking results in the failure of grass carp reovirus cellular entry
... and macropinocytosis pathways were considered to be the most likely candidates for GCRV entry. LY294002 is an in- hibitor of PI3K by preventing cup closure but not ruffle closure. PI3-kinase is also implicated in several ...
10
A Functional Polymorphism Mediated Disruption of EGR1/ADAM10 Pathway Confers the Risk of Sepsis Progression
... EGR1 (also known as NGFI-A, krox-24, Zif268, or TIS8) encodes a Cys2-His2-type zinc finger TF that belongs to the member of the immediate early gene family, and its expression is rapidly elicited in response to a variety ...
13
Ultrasound Induced Microalgal Cell Disruption: Experimental and Computational Research
... wave and surface friction result in strong shear tensions to break up the liquid into a chain of uniform droplets [19]. However, to the best knowledge of the authors, combining ultrasound treatment and liquid spraying ...
200
Disruption in the diabetic device care market
... Diabetes Care Devices Market, by Type (Blood Glucose Monitoring Devices, Insulin Delivery Devices), End-users (Hospitals, Homecare, Others) - Global Revenue, Trends, Growth, Share, Si[r] ...
6
“My cancer is not my deepest concern”: life course disruption influencing patient pathways and health care needs among persons living with colorectal cancer
... biographical disruption, not only related to receiving the diagnosis and living with cancer, but also with respect to disruptive events before becoming a cancer ...the disruption literature adds to a deeper ...
10
Half A Century Of Migration And Family Formation In Latin America And The Caribbean
... with ages of transition to union formation and childbearing. To the extent that both acts require resources (time, money, social support, etc.), their temporal coincidence may be more demanding for low-SES individuals ...
143
NMDA Receptor Dysfunction and Development of Translational Biomarkers for Autism and Schizophrenia
... relative disruption of interneurons and pyramidal cells following NMDA-receptor blockade, however it is not possible to quantify that distribution using the systemic administration drug ...the disruption is ...
103
When Women with Cystic Fibrosis Become Mothers: Psychosocial Impact and Adjustments
... little disruption and disruption being broadly time-limited, (ii) the utilisation of social support is not the only way of cop- ing with good evidence of other forms of “problem-solving” and displaying of ...
12
Optimisation of DNA extraction from the crustacean Daphnia
... tissue disruption where DNA quantification based on absorbance is very similar to the gold standard fluorescence method of DNA quantification, SYBR Green I (Two-way ANOVA, p > ...
17
Conductive Hearing Loss with Present Acoustic Reflex: A Case Report
... AR is a sensitive indicator of middle ear lesions and the lack of AR usually indicates a disruption of the ossicu- lar chain, including ossicular discontinuity and fixation. However, the present case showed that ...
6
Melatonin and Circadian Rhythm: Aging, Cancer, and Mechanism
... The circadian clock is an endogenous time keeping system shared by most organisms [41]. In mammals, a master pacemaker in the hypothalamus orchestrates temporal alignment of behavior and physiology by transmit- ting ...
17
HIV associated disruption of lung cytokine networks is incompletely restored in asymptomatic HIV infected Malawian adults on antiretroviral therapy
... This is thought to occur in response to HIV antigens and forms part of the host response to the presence of HIV in the lung [2, 3]. Excessive influx of inflammatory cells in the lung probably leads to tissue damage, ...
5
A comparative study of extraction techniques for maximum recovery of glutamate decarboxylase (GAD) from Aspergillus oryzae NSK
... the disruption of mycelia cell becomes less effective, which can be observed from Figure 2a where GAD activity and soluble proteins were started to decline at 12% of cell ...
9
The THO complex is required for nucleolar integrity in Drosophila spermatocytes
... During Drosophila spermatogenesis, tTAFs encoded by can-class meiotic arrest genes are known as the key players in terminal differentiation for coordinated transcriptional activation of several spermiogenesis-related ...
11
A Novel Small Molecule, 1,3-di-m-tolyl-urea, Inhibits and Disrupts Multispecies Oral Biofilms
... nucleatum (Figure S2). Selective disruption of the biomass of the bridge colonizer F. nucleatum may explain the effects on multispecies biofilms. To confirm if disruption of[r] ...
11
Managing supply chain disruptions: role of firm resilience and strategic focus on innovation
... First, organizations need a clear risk management policy to strengthen management of risks associated with innovations through proactive risk identification, risk acceptance and risk management. The policy will ensure ...
95
Calcineurin Is Essential for Candida albicans Survival in Serum and Virulence
... membrane disruption activity of the AMPs is reminiscent of the mem- brane disruption caused by fluconazole, which is lethal to strains lacking calcineurin but only fungistatic to strains with active ...
9
The Complete Makeover of Cloud Computing in the Next Decade, Will You Survive?: A Prophetic Approach
... Therefore, Forrester decided to focus instead on the major disruption in the IT industry that cloud computing is bringing about — disruption based not on technology but on the business m[r] ...
13