Disseminated candidiasis
Physiologic Expression of the Candida albicans Pescadillo Homolog Is Required for Virulence in a Murine Model of Hematogenously Disseminated Candidiasis
... Physiologic PES1 expression is required for full virulence of C. albicans in a murine model of hematogenously disseminated candidiasis. To determine the effect of PES1 expression on viru- lence of C. ...
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Intestinal Lesions Associated with Disseminated Candidiasis in an Experimental Animal Model
... In this study, oral inoculation of a highly susceptible animal was used to develop an experimental model for gastrointestinal and disseminated candidiasis. Gnotobiotic (GB) infant piglets were chosen for ...
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Live Imaging of Disseminated Candidiasis in Zebrafish Reveals Role of Phagocyte Oxidase in Limiting Filamentous Growth
... lethal disseminated disease that shares important traits with disseminated candidiasis in mammals, including dimorphic fungal growth, dependence on hyphal growth for virulence, and dependence on the ...
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Chronic disseminated candidiasis manifesting as hepatosplenic abscesses among patients with hematological malignancies
... invasive candidiasis [1, 2]. Chronic disseminated candidiasis (CDC) is a unique clinical manifestation of invasive candidiasis; it usually develops during recovery from neutropenia after ...
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Leukocyte myeloperoxidase deficiency and disseminated candidiasis: the role of myeloperoxidase in resistance to Candida infection
... These findings suggest that hereditary MPO deficiency is transmitted as an autosomal recessive characteristic, that the homozygous state conveys enhanced susceptibility to disseminated candidiasis, and that ...
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Competitive Binding Inhibition Enzyme-Linked Immunosorbent Assay That Uses the Secreted Aspartyl Proteinase of Candida albicans as an Antigenic Marker for Diagnosis of Disseminated Candidiasis
... acute disseminated candidiasis (found in both oncologic and nononcologic patients [59]) rather than the chronic, hepato- splenic infection most often observed in patients treated for acute leukemia and in ...
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Diagnosis of disseminated candidiasis by measurement of urine D arabinitol/L arabinitol ratio
... of disseminated yeast infection in leukemia patients using colonized patients and neutropenic patients without infection as a reference population in addition to healthy ...
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Gas chromatographic determination of D arabinitol/L arabinitol ratios in urine: a potential method for diagnosis of disseminated candidiasis
... To determine intraindividual variation over time, six urine samples were collected from each of 20 individuals one sample every second day; 10 individuals were healthy adults and childre[r] ...
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Candida antigenemia, as detected by passive hemagglutination inhibition, in patients with disseminated candidiasis or Candida colonization
... If just the complete reactions are considered, then 50% of patients with disseminated invasive candidiasis were positive for circulating antigen, whereas all of the colonized patients an[r] ...
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Candida Antigen Detection in Two Premature Neonates with Disseminated Candidiasis
... had systemic candidiasis; we utilized a rapid, en- zyme-linked immunosorbent assay for the Candida antigen mannan.’#{176} Mannan detection is useful in the evaluation of invasive candidi[r] ...
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Comparison of serum mannan, arabinitol, and mannose in experimental disseminated candidiasis
... Elevated concentrations of mannose, adjusted for renal function, and elevated arabinitol/creatinine ratios were observed in both infected and uninfected animals receiving cortisone aceta[r] ...
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Recovery From Disseminated Candidiasis in a Premature Neonate
... Four days later, after three negative blood cultures and a negative cerebrospinal fluid culture were obtained, the amphotericin B was discontinued.. On the 26th hospital day, 17 days aft[r] ...
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Micafungin: an evidence-based review of its place in therapy
... esophageal candidiasis and prophylaxis of invasive Candida infections in patients undergoing hematopoietic stem cell ...acute disseminated candidiasis, Candida abscesses, and ...
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Diagnostic value of the enzyme linked immunosorbent assay for detection of Candida albicans cytoplasmic antigen in sera of cancer patients
... All seven patients with proven disseminated candidiasis showed high concentrations of cytoplasmic antigen ranging from 500 tt 1,700 ng/ml X = 1,200 ng/ml.. Four patients in this group ha[r] ...
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Nonvalue of antigen detection immunoassays for diagnosis of candidemia
... Outlines of the various clinical groups and Cand-Tec titers in sera from candidemic patients, negative control patients, and those with focal and disseminated candidiasis with organ invo[r] ...
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In Vitro and In Vivo antifungal activities of selected Cameroonian dietary spices
... the control (Figure 1A). At this extract concentration, the number of cfu/mL in blood dropped below the de- tection limit within 72 h, while the control (nystatin) showed similar effect within 48 h. This result suggests ...
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Distinct Roles of Candida albicans-Specific Genes in Host-Pathogen Interactions
... Human fungal pathogens are distributed throughout their kingdom, suggesting that pathogenic potential evolved indepen- dently. Candida albicans is the most virulent member of the CUG clade of yeasts and a common cause of ...
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ERG2 and ERG24 Are Required for Normal Vacuolar Physiology as Well as Candida albicans Pathogenicity in a Murine Model of Disseminated but Not Vaginal Candidiasis
... Given their reduced growth rates, deficiencies in stress toler- ance, reduced protease secretion, and impaired hyphal growth, we were anticipating that both the erg2⌬/⌬ and erg24⌬/⌬ mutants would be avirulent in vivo. ...
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Comparison of antibody, antigen, and metabolite assays for hospitalized patients with disseminated or peripheral candidiasis
... Repeat serum samples from 22 patients with proven disseminated candidiasis and 42 with simple peripheral colonization were assayed for Candida antibodies by coelectrosyneresis, immunopre[r] ...
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Oral Candidiasis in Human Immunodeficiency Virus Patients and Its Correlation with CD4 Count
... Oral candidiasis (49 [59%]) was found to be the most common oral lesion among the 83 HIV-infected ...of candidiasis, erythematous candidiasis ...
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