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Distemper Virus, Canine

Disease Duration Determines Canine Distemper Virus Neurovirulence

Disease Duration Determines Canine Distemper Virus Neurovirulence

... Canine distemper virus (CDV), which infects a broad range of carnivores, is a close relative of the human pathogen mea- sles virus (MV) ...

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Canine Distemper Virus Antigen Detection in External Epithelia of Recently Vaccinated, Sick Dogs by Fluorescence Microscopy Is a Valuable Prognostic Indicator

Canine Distemper Virus Antigen Detection in External Epithelia of Recently Vaccinated, Sick Dogs by Fluorescence Microscopy Is a Valuable Prognostic Indicator

... replicating virus in the external epithelia in field ...included canine clients from a well-managed clinic with complete records on vaccination, history of respiratory sickness, and clinical out- comes ...

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Phylogenetic analysis of canine distemper virus in South African wildlife

Phylogenetic analysis of canine distemper virus in South African wildlife

... Canine distemper virus strains were recovered from three different regions in South Africa and were sampled from AWD and domestic dog from the Tswalu Kalahari Reserve, Northern Cape Province; AWD ...

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Detection of Arctic and European cluster of canine distemper virus in north and center of Iran

Detection of Arctic and European cluster of canine distemper virus in north and center of Iran

... The authors present their special thanks to Dr. Chrysostomos Dovas (Aristitol University, Thessaloniki, Greece) and Dr. Seuberlich Torsten (Neuro Centre, National and OIE Reference Laboratory for BSE and Scrapie, ...

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Establishment of a Rescue System for Canine Distemper Virus

Establishment of a Rescue System for Canine Distemper Virus

... Canine distemper virus (CDV) has been rescued from a full-length cDNA ...Measles virus (MV) and Rinderpest virus, a third morbillivirus is now available for genetic analysis using ...

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Phylogenetic analysis of the wild type strains of canine distemper virus circulating in the United States

Phylogenetic analysis of the wild type strains of canine distemper virus circulating in the United States

... Canine distemper (CD) is a highly contagious, systemic viral disease of dogs seen ...worldwide. Canine distemper virus (CDV), the causative agent of CD, is an enveloped virus in ...

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Canine Distemper Virus Spread and Transmission to Naive Ferrets: Selective Pressure on Signaling Lymphocyte Activation Molecule-Dependent Entry

Canine Distemper Virus Spread and Transmission to Naive Ferrets: Selective Pressure on Signaling Lymphocyte Activation Molecule-Dependent Entry

... measles virus, rinderpest virus, and canine distemper virus (CDV) initially target immune cells via the signaling lym- phocyte activation molecule (SLAM) before spreading to respiratory ...

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Canine distemper virus persistence in the nervous system is associated with noncytolytic selective virus spread.

Canine distemper virus persistence in the nervous system is associated with noncytolytic selective virus spread.

... Canine distemper virus (CDV), a negative-strand RNA mor- billivirus related to measles virus, causes in dogs and other carnivores a naturally occurring demyelinating disease which is ...

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The Hemagglutinin of Canine Distemper Virus Determines Tropism and Cytopathogenicity

The Hemagglutinin of Canine Distemper Virus Determines Tropism and Cytopathogenicity

... certain canine cells: MV grows to high titers in MDCK cells (22) and in the thymic canine cell line Cf2Th (data not ...be canine CD46 (22). Not all canine cell lines express this receptor: in ...

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Canine Distemper Virus Infection Requires Cholesterol in the Viral Envelope

Canine Distemper Virus Infection Requires Cholesterol in the Viral Envelope

... for virus entry for several reasons. For influenza virus it has been shown that depletion of cholesterol from the viral envelope reduces infec- tivity (39) and that this effect was caused by inhibition of ...

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Identification of a novel linear B cell epitope using a monoclonal antibody against the carboxy terminus of the canine distemper virus nucleoprotein and sequence analysis of the identified epitope in different CDV isolates

Identification of a novel linear B cell epitope using a monoclonal antibody against the carboxy terminus of the canine distemper virus nucleoprotein and sequence analysis of the identified epitope in different CDV isolates

... RNA was extracted from Vero cells infected with wild- type CDV Chinese strains. The extraction was done as in- dicated above. The first-strand cDNAs were synthesized using random primers. For each virus, the ...

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Nearby Clusters of Hemagglutinin Residues Sustain SLAM-Dependent Canine Distemper Virus Entry in Peripheral Blood Mononuclear Cells

Nearby Clusters of Hemagglutinin Residues Sustain SLAM-Dependent Canine Distemper Virus Entry in Peripheral Blood Mononuclear Cells

... vaccinia virus (MVA/T7) (33) and transfected with the plasmid containing the full-length CDV genome as well as expression plasmids for the CDV nucleo-, phospho-, and polymerase ...of canine SLAM-expressing ...

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Canine Distemper Virus detection based in Hemaglutinine Gene as target in Reverse Transcriptase-Polymerase Chain Reaction

Canine Distemper Virus detection based in Hemaglutinine Gene as target in Reverse Transcriptase-Polymerase Chain Reaction

... Canine Distemper have become a major concern within the veterinary clinical ...of canine distemper in adult animals with their vaccination plan up to date has alarmed ...of canine ...

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Molecular and Serological Detection of Canine Distemper Virus (CDV) in Rural Dogs, Iran

Molecular and Serological Detection of Canine Distemper Virus (CDV) in Rural Dogs, Iran

... of canine distemper virus isolates in fur animals from various vaccine strains by reverse transcription-polymerase chain reactionrestriction fragment length polymorphism according to phylogenetic ...

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6 methylmercaptopurine riboside, a thiopurine nucleoside with antiviral activity against canine distemper virus in vitro

6 methylmercaptopurine riboside, a thiopurine nucleoside with antiviral activity against canine distemper virus in vitro

... Initially, negative-stranded RNA viruses direct the RNA synthesis machinery to mRNA production. Replication pro- cesses are then initiated [30]. Both transcription and gen- ome replication events of paramyxoviruses are ...

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Phylogenetic analysis of canine distemper virus detected in Chile

Phylogenetic analysis of canine distemper virus detected in Chile

... For the following samples, all were considered positive for the CDV-specific IgM test with antibody titers greater than 1:40 and worked within a period of less than two weeks from obtaining the host to processing. Of the ...

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Sequencing of emerging canine distemper virus strain reveals new distinct genetic lineage in the United States associated with disease in wildlife and domestic canine populations

Sequencing of emerging canine distemper virus strain reveals new distinct genetic lineage in the United States associated with disease in wildlife and domestic canine populations

... While there have recently been multiple reports of new genotypes/lineages, questions remain as to whether the genetic differences represent significant differences in anti- genicity. It has been suggested that changes in ...

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Tropism and molecular pathogenesis of canine distemper virus

Tropism and molecular pathogenesis of canine distemper virus

... [3]. Virus persist- ence in the CNS can be observed with some CDV strains, for instance the A75/17 strain, when the virus is capable of spreading to some areas of the brain without eliciting an inflammatory ...

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Morbilliviruses Use Signaling Lymphocyte Activation Molecules (CD150) as Cellular Receptors

Morbilliviruses Use Signaling Lymphocyte Activation Molecules (CD150) as Cellular Receptors

... measles virus, canine distemper virus, rinderpest virus, and several other viruses that cause devastating human and animal diseases accompanied by severe immunosuppression and lympho- ...

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Formation of Syncytia Is Repressed by Tetraspanins in Human Immunodeficiency Virus Type 1-Producing Cells

Formation of Syncytia Is Repressed by Tetraspanins in Human Immunodeficiency Virus Type 1-Producing Cells

... regulate virus-induced fusion ...by canine distemper virus, as the anti-CD9 antibody K41 inhibits syncy- tium formation by this virus (42), and CD81 is a necessary * Corresponding ...

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