DNA and Cellular Damage
Meningitis Induced by Streptococcus Pneumoniae Elicits Cellular Damage but not DNA Damage during the Acute Phase of Infection in the Hippocampus of Wistar Rats
... quantified. DNA damage was assessed by the alkaline single-cell gel electrophoresis “comet assay” ...no DNA damage observed in all the regions of the hippocampus as a ...showed cellular ...
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Phosphatases in the cellular response to DNA damage
... The data discussed here seems to reveal a scenario where multiple phosphatases target the same phosphor- ylation events. While this could be construed as exces- sive promiscuity of phosphatases we believe that a more ...
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Cellular response to dental monomers - Involvment of oxidative stress and DNA damage
... of DNA damage repair, protecting cells from copying damaged DNA [63, ...by DNA damage and activation of repair mechanisms induced by GDMA and ...
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Effects of trypsin on cellular, chromosomal and DNA damage induced by X rays
... Culture: methods and applications.(ed. London: Academic Press. The ovalbumin gene is associated with the nuclear matrix of chicken oviduct cells. Association of globin ribonucleic acid[r] ...
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Spy1 Regulation of the DNA Damage Response; Checkpoint Activation and Cellular Senescence
... and DNA damage-induced G1 checkpoint At a key regulatory site in G1, termed the “restriction point”, cells respond to the stimulation from appropriate growth factor ...their DNA or withdraw from the ...
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Serotype-Specific Inactivation of the Cellular DNA Damage Response during Adenovirus Infection
... the DNA damage repair pathways during infection with Ad3, Ad7, Ad9, and Ad11, we considered the possibility that these viruses had evolved such that they might be able to tolerate the concatemerization of a ...
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Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence
... Background: Cellular senescence is a state reached by normal mammalian cells after a finite number of cell divisions and is characterized by morphological and physiological changes including terminal cell-cycle ...
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LKB1 is a DNA damage response protein that regulates cellular sensitivity to PARP inhibitors
... in DNA repair is increased radiation sensitivity, and hence extensive apoptotic cell death following ...against DNA damage and repair of SSB-induced DNA damage ...DSB DNA repair ...
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The Papillomavirus E1 Helicase Activates a Cellular DNA Damage Response in Viral Replication Foci
... host cellular factors to replicate the viral ...a DNA damage response, resulting in phosphorylation of ATM, Chk2, and ...active DNA repair, as evidenced by incorporation of nucleotide analogs ...
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MAPKinase signaling and AP-1-regulated gene expression in cellular responses to DNA damage
... tussen DNA-schade in getranskribeerde genen en de MKP-1-JNK ...op DNA replikatie en transkriptie zijn in een aantal opzichten vergelijkbaar met de effekten van ...gereguleerde DNA herstel ...
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DNA damage and cellular abnormalities in tuberculosis, lung cancer and chronic obstructive pulmonary disease
... and/or DNA repair ...for DNA metabolism can also play a role in the process of MN formation ...of DNA damage in specific ...[12]. Damage to the oral epithelium indirectly indicates ...
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Epigenetic mechanisms involved in the cellular response to DNA damage processed by Base Excision Repair
... to DNA it bends the DNA to approximately 35° and the helical axis kinked to roughly ...with DNA phosphate on the opposite strand, and tyrosine (Y) 128 and glycine (G) 127 cross and widened the minor ...
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Enhancer function driving cellular senescence, DNA damage repair, differentiation, and nuclear organization
... other DNA damage repair pathways might also be recruited to AR-regulated ...double-strand DNA break ends), Exonuclease 1 (EXO1), the Bloom syndrome DNA helicase (BLM), and DNA ligase IV ...
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Differential Activation of Cellular DNA Damage Responses by Replication-Defective and Replication-Competent Adenovirus Mutants
... However, AdRSV gal does express E4-11kDa, albeit at reduced levels compared to Ad5 (Fig. 2B), and could therefore affect the distribution of Mre11. We measured Mre11 levels and its distri- bution in AdRSV gal ...
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Phenolic compounds isolated from Pilea microphylla prevent radiation-induced cellular DNA damage
... required for optimal antioxidant potency in vitro and in cell- based systems. Therefore, the interplay of hydrophilic and hydrophobic characteristics, together with the flavonoid struc- ture, especially the number and ...
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A Synthetic Circuit For Control Of The Bacterial Dna Damage Response Without Dna Damage
... DNA damage has also been associated with intracellular accumulation of ROS and free radicals, which may also contribute to cell lethality in the absence of ...oxidative damage to DNA, but also ...
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DNA damage induced by acrylamide: roe of genetic polymorphisms in DNA damage levels
... 1.3. DNA Damage 1.3.1. Principles DNA damage is a relatively common event in the life of a cell and may lead to mutation, cancer and cellular or organismic death ...in DNA ...
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Review on DNA damage, repair and DNA sequencing
... corrects damage to the DNA molecules that encode its ...cause DNA damage, Many of these lesions cause structural damage to the DNA molecule and can alter or eliminate the cell's ...
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MAPKinase signaling and AP-1-regulated gene expression in cellular responses to DNA damage Hamdi, M.
... UV-induced DNA damage induces apoptosis in TCR-deficient human ...of DNA damage in the transcribed strand of active genes, at UV doses that are cytotoxic for TCR-deficient fibroblasts, but not ...
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DNA damage in Molt-4 T-lymphoblastoid cells exposed to cellular telephone radiofrequency fields in vitro
... increased DNA damage in the organs of animals exposed in vivo to microwave ...in DNA dam- age after exposure to SARs of ...in DNA damage after 2 h total incubation time, while expo- ...
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