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DNA Polymerases

A new family of polymerases related to superfamily A DNA polymerases and T7-like DNA-dependent RNA polymerases

A new family of polymerases related to superfamily A DNA polymerases and T7-like DNA-dependent RNA polymerases

... between DNA polymerases and primases of different folds with diverse DNA helicases, especially those of the ring- forming AAA+ and RecA superfamilies of P-loop NTPases ...of DNA ...

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Purification, Characterization, and Comparison of the DNA Polymerases from Two Primate RNA Tumor Viruses

Purification, Characterization, and Comparison of the DNA Polymerases from Two Primate RNA Tumor Viruses

... 431-439 Copyright 0 1973 American Society for Microbiology Purification, Characterization, and Comparison of the DNA Polymerases from Two Primate RNA Tumor Viruses Received for publicati[r] ...

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A highly conserved family of inactivated archaeal B family DNA polymerases

A highly conserved family of inactivated archaeal B family DNA polymerases

... Inactivation of the enzymatic function of a protein and utilization of the inactivated protein for non-enzymatic (structural) roles, so that it retains substantial sequence conservation, is not without precedent. ...

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Temporal order of evolution of DNA replication systems inferred by comparison of cellular and viral DNA polymerases

Temporal order of evolution of DNA replication systems inferred by comparison of cellular and viral DNA polymerases

... different DNA replication systems, drawing argument from the differences in their representation among viruses and other selfish replicating ...the DNA replication systems of viruses infecting bacteria and ...

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Regulation of DNA Polymerase Exonucleolytic Proofreading Activity: Studies of Bacteriophage T4 “Antimutator” DNA Polymerases

Regulation of DNA Polymerase Exonucleolytic Proofreading Activity: Studies of Bacteriophage T4 “Antimutator” DNA Polymerases

... DNA polymerases ( Gauss et ...increased DNA replication accuracy is the possible necessity of a certain minimal mutation rate that is sufficient to allow an organism to adapt to fluctuations in the ...

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Transcription of 70S RNA by DNA polymerases from mammalian RNA viruses.

Transcription of 70S RNA by DNA polymerases from mammalian RNA viruses.

... Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest DNA polymerases purified by the same procedure from four mammalian RNA viruses, simian sarcoma virus type 1, gibbon ape [r] ...

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Lack of Serological Relationship Among DNA Polymerases of Avian Leukosis-Sarcoma Viruses, Reticuloendotheliosis Viruses, and Chicken Cells

Lack of Serological Relationship Among DNA Polymerases of Avian Leukosis-Sarcoma Viruses, Reticuloendotheliosis Viruses, and Chicken Cells

... Lack of Serological Relationship Among DNA Polymerases of Avian Leukosis-Sarcoma Viruses, Reticuloendotheliosis Viruses, and Chicken Cells Received for publication 30 May 1973 Antibodies[r] ...

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Three Mitochondrial DNA Polymerases Are Essential for Kinetoplast DNA Replication and Survival of Bloodstream Form Trypanosoma brucei

Three Mitochondrial DNA Polymerases Are Essential for Kinetoplast DNA Replication and Survival of Bloodstream Form Trypanosoma brucei

... three DNA polymerases, we found that parasites that survived RNAi (pro- liferated in clonogenic assays) still contained intact kDNA networks and remained responsive to induction for RNAi, as evidenced from ...

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Influence of salts and pcr inhibitors on the amplification capacity of three thermostable DNA polymerases

Influence of salts and pcr inhibitors on the amplification capacity of three thermostable DNA polymerases

... plify DNA more efficiently in the presence of in- hibitors without the need for extensive sample processing prior to ...rified DNA, obtained by rapid and inexpensive procedures to be suitable for PCR ...one ...

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Structural insights into DNA replication and lesion bypass by Y family DNA polymerases

Structural insights into DNA replication and lesion bypass by Y family DNA polymerases

... by DNA polymerases leads to replicative stress and genome instability (Nick McElhinny et ...all DNA polymerases that must be highly specific, in part, due to the excess of NTP concentrations ...

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Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol ε and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors

Evolution of DNA polymerases: an inactivated polymerase-exonuclease module in Pol ε and a chimeric origin of eukaryotic polymerases from two classes of archaeal ancestors

... B-family DNA polymerases ...B-family polymerases (PolBI) that is represented in nearly all archaea, whereas the rest of the eukaryotic B- family polymerases including the inactivated ...

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Contrasting Effects of W781V and W780V Mutations in Helix N of Herpes Simplex Virus 1 and Human Cytomegalovirus DNA Polymerases on Antiviral Drug Susceptibility

Contrasting Effects of W781V and W780V Mutations in Helix N of Herpes Simplex Virus 1 and Human Cytomegalovirus DNA Polymerases on Antiviral Drug Susceptibility

... This work was supported by a grant from the Consortium Québécois sur la Découverte du Médicament (CQDM) to M.G. and G.B. G.B. is the FIG 4 Structural orientation of the fingers domain in gp43, UL30, and UL54 DNA ...

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A nucleotide binding rectification Brownian ratchet model for translocation of Y-family DNA polymerases

A nucleotide binding rectification Brownian ratchet model for translocation of Y-family DNA polymerases

... Y-family DNA polymerases are characterized by low-fidelity synthesis on undamaged DNA and ability to catalyze translesion synthesis over the damaged ...the DNA template is an important event ...

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DNA polymerases in polyoma virus-infected mouse kidney cells.

DNA polymerases in polyoma virus-infected mouse kidney cells.

... DNA Polymerases in Polyoma Virus-Infected Mouse Kidney Cells Infection of arrested mouse kidney cells by polyoma virus results in the induction of the cellular 6-8S DNA polymerase activi[r] ...

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Mechanism of inhibition of herpes simplex virus and vaccinia virus DNA polymerases by aphidicolin, a highly specific inhibitor of DNA replication in eucaryotes.

Mechanism of inhibition of herpes simplex virus and vaccinia virus DNA polymerases by aphidicolin, a highly specific inhibitor of DNA replication in eucaryotes.

... Now, in the light of the observed competitive inhibition with dCTP of HSV-1, vaccinia virus, and HeLa cell replicative DNA polymerases by aphidicolin, we studied the inhibition of these [r] ...

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Specific antigenic relationships between the RNA-dependent DNA polymerases of avian reticuloendotheliosis viruses and mammalian type C retroviruses.

Specific antigenic relationships between the RNA-dependent DNA polymerases of avian reticuloendotheliosis viruses and mammalian type C retroviruses.

... DNA polymerases of avain leukosis viruses, pheasant viruses, and mammalian type B and D retroviruses and particles with RNA-dependent DNA polymerase activity from the allantoic fluid of [r] ...

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Distinguishing cytomegalovirus, mycoplasma, and cellular DNA polymerases.

Distinguishing cytomegalovirus, mycoplasma, and cellular DNA polymerases.

... The time course of appearance of salt- NH42SO4, the virus-induced DNA polymerase stimulated DNA polymerase activity in total- activity in total-cell extracts can be readily discell extra[r] ...

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Radioimmunological comparison of the DNA polymerases of avian retroviruses.

Radioimmunological comparison of the DNA polymerases of avian retroviruses.

... We extended the previous competition immunoassay "251-labeled AMV DNA polymerase and antibody to APV DNA polymerase by including several members of the ALV species subgroups A through F,[r] ...

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What is the orientation of DNA polymerases on their templates?

What is the orientation of DNA polymerases on their templates?

... acid polymerases and the orientation of the template-primers relative to the poly- merase active ...coli DNA polymerase I) showed a large groove into which DNA might bind but did not provide ...

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Two DNA polymerases may be required for synthesis of the lagging DNA strand of simian virus 40.

Two DNA polymerases may be required for synthesis of the lagging DNA strand of simian virus 40.

... In contrast, the residual incorporation into the long chains that occurred in the presence of aphidicolin was expected to be confined to leading portions, since synthesis of Okazaki piec[r] ...

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