Dorsal-root ganglion
Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret
... activities. Dorsal root ganglion (DRG) neurons form a circuit that relays signals from peripheral sensory organs to the central nervous ...the dorsal funiculus proceed to the dorsal ...
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Anterograde Glycoprotein-Dependent Transport of Newly Generated Rabies Virus in Dorsal Root Ganglion Neurons
... Rabies virus (RABV) spread is widely accepted to occur only by retrograde axonal transport. However, examples of anterograde RABV spread in peripheral neurons such as dorsal root ganglion (DRG) ...
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Role of Nuclear Factor-κB in Oxidative Stress Associated with Rabies Virus Infection of Adult Rat Dorsal Root Ganglion Neurons
... rat dorsal root ganglion (DRG) neurons infected with the chal- lenge virus standard-11 strain of rabies virus (CVS) showed axonal swellings and immunostaining for 4-hydroxy-2-nonenal (4- HNE), ...
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Opiate mediated inhibition of calcium signaling is decreased in dorsal root ganglion neurons from the diabetic BB/W rat
... capsaicin-sensitive dorsal root ganglion (DRG) neurons from the spontaneously diabetic BioBreeding/ Worcester (BB/W)-rat model of type I human diabetes melli- tus ...in dorsal root ...
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Anterograde Transport of Herpes Simplex Virus Type 1 in Cultured, Dissociated Human and Rat Dorsal Root Ganglion Neurons
... The mechanism of anterograde transport of herpes simplex virus was studied in cultured dissociated human and rat dorsal root ganglion neurons. The neurons were infected with HSV-1 to examine the ...
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In Rat Dorsal Root Ganglion Neurons, Herpes Simplex Virus Type 1 Tegument Forms in the Cytoplasm of the Cell Body
... The herpes simplex virus type 1 (HSV-1) tegument is the least understood component of the virion, and the mechanism of tegument assembly and incorporation into virions during viral egress has not yet been eluci- dated. ...
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The efficacy of pulsed radiofrequency intervention of the lumbar dorsal root ganglion in patients with chronic lumbar radicular pain
... 14. Cho YW, Hwang SJ, Cho HK, Ahn SH, Kim EH, Sluijter ME. Changes in pain behavior and glial activation in the spinal dorsal horn after pulsed radiofrequency current administration to the dorsal ...
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Cisplatin induced apoptosis in rat dorsal root ganglion neurons is associated with attempted entry into the cell cycle
... The reason for predominant sensory neuron toxicity may relate to drug access rather than selective neuronal vulnerabil- ity. Cisplatin does not cross the blood–brain barrier and, there- fore, motor neurons and other ...
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Role of Oxidative Stress in Rabies Virus Infection of Adult Mouse Dorsal Root Ganglion Neurons
... Rabies is an acute viral infection of the central nervous system (CNS) that is usually fatal in humans and animals (10). Despite its lethality, under natural conditions only relatively mild histopathological lesions are ...
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Assessing the effectiveness of ‘pulse radiofrequency treatment of dorsal root ganglion’ in patients with chronic lumbar radicular pain: study protocol for a randomized control trial
... nerve root after it exists from the spinal canal, and before it becomes a part of the somatic ...The dorsal root ganglion (DRG) has been implicated in its pathogenesis by giving rise to ...
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Modulation of dorsal root ganglion development by ErbB signaling and the scaffold protein Sorbs3
... severe reductions in DRG in ouchless mutants (Fig. 1C,D). The few DRG that develop are most frequently found in the first eight segments. ouchless DRG contain fewer neurons than those in wild type (supplementary material ...
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A randomised, patient assessor blinded, sham controlled trial of external non invasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN PENS trial): study protocol for a randomised controlled trial
... DRG: dorsal root ganglion (stimulation); EN-PENS: External non-invasive peripheral nerve stimulation; GCP: Good clinical practice; GMC: General medical council; Hz: Hertz; LTD: Long-term depression; ...
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Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor alpha antagonism
... Lumbar radiculopathy was examined using a surgical model described previously [9]. Briefly, rats were anesthe- tized with intraperitoneal pentobarbital (60 mg/kg) and maintained on 2% isoflurane via mask inhalation for ...
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Treatment of peripheral diabetic neuropathy in Zucker diabetic fatty (ZDF) rats with cariporide
... and dorsal root ganglion were also ...in dorsal root ganglion neurons was in- creased in ZDF ...and dorsal root ganglion ...
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An Immortalized Human Dorsal Root Ganglion Cell Line Provides a Novel Context To Study Herpes Simplex Virus 1 Latency and Reactivation
... ABSTRACT A defining characteristic of alphaherpesviruses is the establishment of lifelong latency in host sensory ganglia with occasional reactivation causing recur- rent lytic infections. As an alternative to rodent ...
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Morphologic Analysis of Normal Human Lumbar Dorsal Root Ganglion by 3D MR Imaging
... the bifurcated spinal nerve into 3 types: type A, type B, and type C, according to the connecting patterns of the DRGs. Comparatively, the singular ganglion in our study coin- cides with their types A and B DRGs, ...
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The Endocannabinoid, 2 Arachidonoyl Glycerol, Induces Growth Cone Collapse and Neurite Retraction in Growing Peripheral Sensory Neurons
... Cannabis has a detrimental impact on the developing nervous system. Therefore, regular con- sumption of cannabis by pregnant and lactating woman poses a potential risk to neuronal growth in fetuses and infants. Indeed, ...
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Nerve growth factor: from the early discoveries to the potential clinical use
... the dorsal root gan- glion (DRG) the expression of neuropeptides such as Substance P (SP) and Calcitonin Gene-Related Peptide (CGRP) by primary sensory neurons is under NGF con- trol [18] and in vivo ...
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Upregulation of CXCL10 in Human Dorsal Root Ganglia during Experimental and Natural Varicella-Zoster Virus Infection
... FIG. 4. CXCL10 and CXCR3 detection in naturally infected human ganglia during herpes zoster. From a patient who died with a herpes zoster rash but not from VZV-related causes, two dorsal root ganglia (DRG) ...
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Increasing expression of substance P and calcitonin gene related peptide in synovial tissue and fluid contribute to the progress of arthritis in developmental dysplasia of the hip
... In this study, we divided patients with DDH into two groups (moderate DDH and severe DDH). By doing so, we aimed to investigate the differences in pathophysio- logical processes and inflammatory conditions between these ...
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