double-blind randomized study
Hospice and Palliative Care: A New Movement in India
... comparative double blind randomized study with 60 patients randomized into two groups with 30 in group A in which epidural Fentanyl ( 50 microgram) followed by top up doses of 15 ...
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Milnacipran and venlafaxine at flexible doses (up to 200 mg/day) in the outpatient treatment of adults with moderate-to-severe major depressive disorder: a 24-week randomized, double-blind exploratory study
... The statistical power required to carry out a non-inferiority analysis was not achieved. However, when considering this limitation, it should be noted that the level of recruitment required to reach this statistical ...
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A multicenter, double-blind, randomized, comparison study of the efficacy and safety of tigecycline to imipenem/cilastatin to treat complicated intra-abdominal infections in hospitalized subjects in China
... Yongjie Zhao, Gang Chen, Ping Li, Jian Lei, Jiye Zhu, Dianrong Xiu, Chungen Xing, Yingyuan Zhang, Jufang Wu, Yijian Chen, Feizhou Huang, Lu Liang, Weilin Wang, Shuanghai Liu, Yongkuan Cao, Tianzheng Lou, Tienan Bi, ...
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VITALITY ALS, a phase III trial of tirasemtiv, a selective fast skeletal muscle troponin activator, as a potential treatment for patients with amyotrophic lateral sclerosis: study design and baseline characteristics
... were randomized to placebo and those randomized to tirasemtiv (pooled three target dose levels) during the placebo-controlled, double-blind ...of double-blind treatment to ...
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Evaluation the effect of dexamethasone on post-dural puncture headache in cesarean surgery
... Methods: This randomized double-blind clinical study was conducted on 104 patients aged from 15 to 45 years. They were in classes 1 or 2 according to the American Society of Anesthesiologists ...
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Everolimus in the treatment of subependymal giant cell astrocytomas, angiomyolipomas, and pulmonary and skin lesions associated with tuberous sclerosis complex
... III, randomized, double-blind, placebo-controlled—A Randomized, Double-blind, Pla- cebo-controlled Study of RAD0001 in the Treatment of Angiomyolipoma in Patients With ...
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Efficacy of combination therapy with ezetimibe and statins versus a double dose of statin monotherapy in participants with hypercholesterolemia: a meta-analysis of literature
... Only double-blind Randomized controlled study (RCTs) of efficacy evaluation in the two groups with eze- timibe and statins and a double dose of statin in partici- pants with ...
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A randomized, double blind trial of Granisetron compared with Dexamethasone in preventing Postoperative Nausea and Vomiting after laparoscopic abdominal surgery at a tertiary care hospital
... The study medication were administered immediately before the induction of ...the study prepared the drugs according to manufacturer’s instructions and placed them in numbered, sealed envelopes assigned by ...
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Comparison of Clonidine & Dexamethasone as Additive to Bupivacaine in Fascia Iliaca Compartment Block for Postoperative Analgesia in Patients Undergoing Lower Limb Orthopaedic Surgery
... Present study was conducted as a controlled, randomized, double blind, prospective study to compare the efficacy of clonidine and dexamethasone as an adjuvant to bupivacaine in FICB for ...
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Randomized, Double-Blind Trial of Olanzapine.pdf
... the study addressed an essentially new clinical en- tity, which required designing new “prodromal” assess- ment instruments and a new definition of psychosis ...
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A prospective randomized double blind study to find out the efficacy of dexmedetomidine 1μcg/kg single infusion as an adjuvant for general anaesthesia
... our study showed that even single loading dose of dexmedetomidine has clinical benefits for surgery of duration of 2 ...Our study proves that dexmedetomidine in single loading dose is an economical and ...
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Chlorproguanil−Dapsone−Artesunate versus Artemether−Lumefantrine : a randomized, double blind phase III trial in African children and adolescents with uncomplicated plasmodium falciparum malaria
... Methods and Findings: The trial was conducted at medical centers at 11 sites in five African countries between June 2006 and August 2007. 1372 patients ($1 to ,15 years old, median age 3 years) with acute uncomplicated ...
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A randomized, double-blind, placebo-controlled, dose-ranging study using Genz-644470 and sevelamer carbonate in hyperphosphatemic chronic kidney disease patients on hemodialysis
... treatment groups and placebo with regard to LDL-cholesterol, total cholesterol, and serum calcium (albumin-adjusted)- phosphorus product. In addition, a comparison of the change from baseline, to day 22/ET between ...
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A randomized, double-blind, placebo-controlled study of oral antioxidant supplement therapy in patients with dry eye syndrome
... This study was a double-blinded, randomized, parallel- group, and placebo-controlled trial aimed to evaluate the efficacy and safety of an oral antioxidant supplement in the treatment of ...the ...
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Randomized, double-blind, placebo-controlled, clinical study on the effect of Diabetinol<sup>®</sup> on glycemic control of subjects with impaired fasting glucose
... The safety analysis was based on all randomized partici- pants who were known to have taken at least one dose of the experimental or placebo product. Participants that did not meet the AACE/ADA-recommended goals ...
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Erenumab in chronic migrainePatient-reported outcomes in a randomized double-blind study
... impact of headaches (>60). At month 3, mean (SE) HIT-6 scores were 57.6 (0.5) for 70 mg and 57.0 (0.6) for 140 mg vs 60.2 (0.4) for placebo and reflected greater changes from baseline. The change from baseline in total ...
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A randomized, double-blind study of hydromorphone hydrochloride extended-release tablets versus oxycodone hydrochloride extended-release tablets for cancer pain: efficacy and safety in Japanese cancer patients (EXHEAL: a Phase III study of EXtended-release HydromorphonE for cAncer pain reLief)
... to study drugs were observed in four patients (hypercalcemia, appetite loss, somnolence, and vomiting in one patient each) in the hydromorphone group and six patients (ileus in two patients, and decreased level of ...
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Children’s International Polyposis (CHIP) study: a randomized, double-blind, placebo-controlled study of celecoxib in children with familial adenomatous polyposis
... Three patients in the celecoxib group experienced SAEs during the treatment period (depression, pneumonia, and peri- orbital cellulitis secondary to sinusitis); none were considered to be related to the study ...
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Randomized, double-blind, placebo-controlled and active-controlled study to assess the relative abuse potential of oxycodone HCl-niacin tablets compared with oxycodone alone in nondependent, recreational opioid users
... ment sequences using a computer-generated randomization schedule in a Williams square design. Each treatment was administered as a single dose with water in the fasted state. Each dose was administered at approximately ...
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Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects
... Subjects were examined at weeks 0, 6, 8, 14, 16, and 22 of the study. Subjects were examined individually at Trinity Hospital, Bangalore, India. During each visit, the following measurements were taken: body ...
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