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Drug-resistant epilepsy

Cost-effectiveness of cannabinoids for pediatric drug-resistant epilepsy: protocol for a systematic review of economic evaluations

Cost-effectiveness of cannabinoids for pediatric drug-resistant epilepsy: protocol for a systematic review of economic evaluations

... Drug-resistant epilepsy (inadequate response to two or more trials of appropriate antiepileptic drugs [1]) affects between 28% and 37% of people with epilepsy [2] and can have profound ...

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Association between ABCB1-T1236C Polymorphism and Drug-Resistant Epilepsy in Iranian Female Patients

Association between ABCB1-T1236C Polymorphism and Drug-Resistant Epilepsy in Iranian Female Patients

... are resistant to several anti-epileptic drugs ...with drug-resistant epilepsy in Iranian ...were drug responsive and 132 drug ...and drug-resistant epilepsy ...

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Functional Connectivity MR Imaging of the Language Network in Patients with Drug Resistant Epilepsy

Functional Connectivity MR Imaging of the Language Network in Patients with Drug Resistant Epilepsy

... with drug- resistant epilepsy underwent an fMRI presurgical assessment to local- ize and lateralize language ...(27%). Epilepsy was cryptoge- netic in 4 (18%) patients, whereas it was ...

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Syncope and Epilepsy coexist in ‘possible’ and ‘drug-resistant’ epilepsy (Overlap between Epilepsy and Syncope Study - OESYS)

Syncope and Epilepsy coexist in ‘possible’ and ‘drug-resistant’ epilepsy (Overlap between Epilepsy and Syncope Study - OESYS)

... “drug-resistantepilepsy followed in the Epilepsy Centers were ...of epilepsy (not enrolled in our study) may be easier recognized, the detection of syncope in patients with “possible” ...

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Characteristics and predictive biomarkers of drug resistant epilepsy -- study in Georgia

Characteristics and predictive biomarkers of drug resistant epilepsy -- study in Georgia

... of drug resistant epilepsy, however, polytherapy also could be considered as a result of epilepsy cases where seizures are difficult to ...

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VNS in drug resistant epilepsy: preliminary report on a small group of patients

VNS in drug resistant epilepsy: preliminary report on a small group of patients

... absence drug-resistant epilepsy showed a reduction in seizure frequency of 91,7% and a reduc- tion in seizure duration of more than 50% after 9 months of ...absence epilepsy according to the ...

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Localizing Seizure Onset Zones in Presurgical Evaluation of Drug Resistant Epilepsy by Electroencephalography/fMRI: Effectiveness of Alternative Thresholding Strategies

Localizing Seizure Onset Zones in Presurgical Evaluation of Drug Resistant Epilepsy by Electroencephalography/fMRI: Effectiveness of Alternative Thresholding Strategies

... Simultaneous EEG/fMRI is an effective noninvasive tool for identifying and localizing the SOZ in patients with focal epi- lepsy. In this study, we evaluated different thresholding strat- egies in EEG/fMRI for the ...

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Role of hippocampal volumetry in drug resistant epilepsy

Role of hippocampal volumetry in drug resistant epilepsy

... for drug resistant epilepsy between the age group of 10-60 years were enrolled in the ...non drug resistant controls and normal healthy individuals were taken from same ...

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Neuroimaging in drug resistant epilepsy

Neuroimaging in drug resistant epilepsy

... Background: Epilepsy is a common serious neurological condition and 30 to 40 % of people with epilepsy have seizures that are not controlled by ...have drug resistant epilepsy if ...

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Oxcarbazepine effectiveness as add-on therapy in Bulgarian patients with drug-resistant epilepsy

Oxcarbazepine effectiveness as add-on therapy in Bulgarian patients with drug-resistant epilepsy

... The study purpose was to perform an open, prospective study on various aspects of oxcarbazepine (OCBZ) effectiveness in Bulgarian patients with drug-resistant epilepsy. The study was performed with ...

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Lamotrigine: how effective is it as add-on therapy in Bulgarian patients with drug-resistant epilepsy

Lamotrigine: how effective is it as add-on therapy in Bulgarian patients with drug-resistant epilepsy

... The study purpose was to perform an open, prospective study on various aspects of Lamotrigine (LTG) effectiveness in Bulgarian patients with drug-resistant epilepsy. The study was performed with the ...

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Managing drug-resistant epilepsy: challenges and solutions

Managing drug-resistant epilepsy: challenges and solutions

... with epilepsy remain refractory to treatment and are said to have drug-resistant epilepsy ...particular epilepsy (associated syndrome/lesion, initial response to AED, and the number and ...

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Long-term EEG monitoring and positron emission tomography in evaluating patients with drug-resistant epilepsy

Long-term EEG monitoring and positron emission tomography in evaluating patients with drug-resistant epilepsy

... after epilepsy surgery as an indicator of accurate EZL and concluded that SSA had a high lateralizing and localizing value especially when combined with interictal as well as ictal scalp EEG, MRI, and PET ...

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Adjunctive use of electroconvulsive therapy in patients with Lennox-Gastaut syndrome and drug-resistant epilepsy: A pilot study

Adjunctive use of electroconvulsive therapy in patients with Lennox-Gastaut syndrome and drug-resistant epilepsy: A pilot study

... lepsy in the pediatric population before (7). All our patients (both children and adults) had severe intellectual handicap and their care-givers consented in writing to their participation, after the scope of the study ...

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Clinical Applications of Simultaneous PET/MR Imaging Using (R) [11C] Verapamil with Cyclosporin A: Preliminary Results on a Surrogate Marker of Drug Resistant Epilepsy

Clinical Applications of Simultaneous PET/MR Imaging Using (R) [11C] Verapamil with Cyclosporin A: Preliminary Results on a Surrogate Marker of Drug Resistant Epilepsy

... with epilepsy to compare the expression of Pgp between patients with DRE and healthy controls, by using the percentage changes in verapamil influx or the efflux rate before and after Pgp inhibitor ...

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β Hydroxybutyrate Detection with Proton MR Spectroscopy in Children with Drug Resistant Epilepsy on the Ketogenic Diet

β Hydroxybutyrate Detection with Proton MR Spectroscopy in Children with Drug Resistant Epilepsy on the Ketogenic Diet

... astatic epilepsy; MCD, malformation of cortical development; LGS, Lennox-Gastaut Syndrome; “Seizure Type”: T, tonic; TS, tonic spasms; GTC, generalized tonic-clonic; MY, myoclonic; AT, atonic; RFL, reflexive ...

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Principles of therapeutic drug monitoring: a case of drug-resistant epilepsy in a dog

Principles of therapeutic drug monitoring: a case of drug-resistant epilepsy in a dog

... clearance of this drug thus with repeated dosing, the metabolic clearance of phenobarbitone is markedly enhanced and this may alter steady state serum concentrations. Typically, significant enzyme induction is ...

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Quantitative Multimodal Mapping Of Seizure Networks In Drug-Resistant Epilepsy

Quantitative Multimodal Mapping Of Seizure Networks In Drug-Resistant Epilepsy

... are drug-resistant ...of drug-resistant epilepsies are localization-related, meaning that there is a presumed focus in the brain from which seizures arise ...

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MR Imaging in the Presurgical Workup of Patients with Drug Resistant Epilepsy

MR Imaging in the Presurgical Workup of Patients with Drug Resistant Epilepsy

... A second large lesion group comprised patients with epilepsy-associated tumors. Sixteen of 21 gan- gliogliomas and eight of 10 DNTs were correctly di- agnosed on the basis of MR imaging findings. Four ...

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Research Progress on Drug-Resistant Bacteria

Research Progress on Drug-Resistant Bacteria

... In summary, bacterial resistance and resistance mechanisms are a very complex problem, both for pathogenic biology and for human social and behavioral reasons. Bacterial resistance is a global problem encountered during ...

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