Drug Screening
A drug screening assay on cancer cells chronically adapted to acidosis
... of drug resistance, likely associated with poor drug efficacy [3, 8, 11, ...acidosis-mediated drug resistance, we developed a drug screening assay to target the colon cancer HCT116 cell ...
15
Navy Drug Screening Program Client Collection Software (NDSP-CCS)
... Before setting up your pool structure, it is important to understand the definition of a pool and how the Drug Screening Program uses pools. A “Pool” is basically a specific group of personnel. Normally a ...
93
Deep Learning Based Drug Screening for Novel Coronavirus 2019-nCov
... of screening tens of thousands of drugs in a short time in a certain emergency situations, such as 2019-nCov ...based drug screening for 2019-nCov_main_protease, and provided potential compound and ...
17
A method to enhance the hit ratio by a combination of structure-based drug screening and ligand-based screening
... silico drug-screening results to achieve a high hit ...silico screening methods can be ...target screening (MSM-MTS) method was adopted as a structure-based screening method, and the ...
10
Combinatorial drug screening identifies compensatory pathway interactions and adaptive resistance mechanisms
... combinatorial drug screening technique can identify pathways that provide compensatory signaling for each other, leading to resistance to single drug ...single drug treatment on the ...
14
Spontaneously-forming spheroids as an in vitro cancer cell model for anticancer drug screening
... Multi-cellular 3-D systems represent a more relevant model of living tissue and can also provide valuable insights into processes that govern cancer progression, metastasis and drug resistance [6, 9]. At present, ...
13
Current status of drug screening and disease modelling in human pluripotent stem cells
... The emerging data for disease modelling and drug screening are encouraging. However, this is a new field with limitations yet to be overcome. Although hESCs are often considered the gold standard, these ...
18
Quantitative modeling and analysis of drug screening data for personalized cancer medicine
... provides information that is independent of the tissue origin. This complementary information could provide functional relationships in the addiction patterns across different subtypes of cancer. The TAS profile ...
70
Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula
... The aim of the present work was to develop and valid- ate an in vitro drug screening assay for S. haematobium newly transformed schistosomula (NTS). In a first step the cercarial emergence rhythms of the ...
8
Design, fabrication and characterization of an electrochemical microfluidic chip for drug screening
... This new version of design is still based on the same chip dimension because of the limitation of the chip holder which is going to be used. Besides electrochemical electrodes used for drug conversion, new fluidic ...
99
Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening
... Organotypic slice cultures are established in the study of brain disorders [80]. The most explored brain area in organotypic slice cultures is the hippocampus. Hippocam- pal organotypic slice cultures are considered ...
18
Drug screening approach combines epigenetic sensitization with immunochemotherapy in cancer
... non-simultaneous drug combinations, and used it to investigate the reprogramming potential of epigenetic ...by screening 60 epigenetic compounds on diffuse large B-cell lymphoma (DLBCL) ...
11
Deep Learning Based Drug Screening for Novel Coronavirus 2019-nCov
... Department of Disease Control, Ministry of Public Health, Thailand Pilailuk,Okada; Siripaporn,Phuygun; Thanutsapa,Thanadachakul; Supaporn,Wacharapluesadee; Sittiporn,Parnmen; Waraw[r] ...
22
Alcohol/Drug Screening and Brief Intervention in the Medical Setting
... that screening and brief intervention (SBI) for alcohol problems does work to reduce risky drinking and its harmful medical and social side effects ...recommended screening tool, an algorithm for providing ...
7
BMS Changes to Drug Screening Codes. Prior Authorization for Drug Screening Codes (G Codes) Beyond Service Limits
... G0431 (drug screen, qualitative; multiple drug classes by high complexity test method (e.g., immunoassay, enzyme assay), per patient encounter) will be used to report more complex testing methods, such as ...
29
Drug Testing in the Workplace - Drug Screening in the Public Sector: Municipalities and Government Workers
... Courts are unlikely to enforce written consent agreements. City of Plainfield, 1 Individual Empl. Von Raab, 2 Individual Empl.. employee had signed as a condition of employme[r] ...
29
Drug and bioactive molecule screening based on a bioelectrical impedance cell culture platform
... for screening of various bioactive ...for drug targeting of molecules in cells are highlighted in this ...paper. Screening of bioactive molecules based on electric cell-substrate impedance sensing is ...
21
Automatic Generation of Drug Concentration Gradient by a Modified Ink-Jet Printer and its Application in Drug Screening
... in drug screening at cellular ...for drug screening. RGB value was used as the output gauge of drug concentrations for the first ...
5
High content screening for drug discovery from traditional Chinese medicine
... and drug screening technologies (high through‑put screening, high content screening and virtual screening) have been widely applied to either identify the drug target of TCM or ...
9
High Throughput Screening For Drug Discovery In Head And Neck Squamous Cell Carcinoma
... the drug screening methodology described above, 23 of the 78 hit compounds (Appendix 2) were selected for drug validation based on three criteria: universal potency (compounds that were broadly ...
100