Drug Sensitivity
Efficient differentially private learning improves drug sensitivity prediction
... of drug sensitivity prediction increases with amount of private data for the proposed robust private linear ...by sensitivity to a drug (left; higher is better) and by weighted probabilistic ...
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Mechanically produced schistosomula as a higher-throughput tools for phenotypic pre-screening in drug sensitivity assays: current research and future trends
... schistosoma drug screening ...performed drug sensitivity assays by applying schistosomulae and adult worms to establish a proof of ...in drug sensitivity ...the drug assay ...
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Study of Organisms Cultured and their Drug Sensitivity in Peritoneal Fluid of Perforation Peritonitis Patient
... I, Dr. SREDHARAN. M, certainly declare that this dissertation titled “STUDY OF ORGANISMS CULTURED AND THEIR DRUG SENSITIVITY IN PERITONEAL FLUID OF PERFORATION PERITONITIS PATIENTS” represents a genuine ...
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A framework for personalized medicine: prediction of drug sensitivity in cancer by proteomic profiling
... and drug sensitivity (drug resistance or ...of drug sensitivity is obtained by a proposed augmented naive Bayesian classifier (ANBC) whose edges between attributes are augmented in the ...
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Cellular Morphology-Mediated Proliferation and Drug Sensitivity of Breast Cancer Cells
... The understanding the interaction between microenvironment and cancer cells is critical subject to tackle metastatic spread of cancer cells and its many associated issues [2-6]. Cancers destroy the normal balanced in the ...
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Development of an in vitro drug sensitivity assay for Trichuris muris first stage larvae
... Resazurin is a colorimetric and fluorescent dye that has been successfully used in in vitro drug sensitivity assays for several parasitic species such as African trypanosomes and more recently for adult T. ...
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Changes in drug sensitivity and anti malarial drug resistance mutations over time among Plasmodium falciparum parasites in Senegal
... High resolution melt (HRM) technology was used to genotype a set of single nucleotide polymorphisms (SNPs) associated with reduced drug sensitivity [19]. Mutations were detected based on changes in DNA se- ...
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Surveillance of drug sensitivity of bacteria in skin ulcer infections
... super drug resistant ...the drug resistance of ...multiple drug resistance of ...and drug sensitivity testing to guide clinical medication and improve the therapeutic ...
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Predict drug sensitivity of cancer cells with pathway activity inference
... to drug therapies ...predict drug responses ...of drug response and further stratify patient population for given drug therapies, with the assumption that cell line models yield clinical rele- ...
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Phenotypic and genotypic drug sensitivity of <em>Mycobacterium tuberculosis</em> complex isolated from South Omo Zone, Southern Ethiopia
... of drug-sensitivity patterns of Mycobacterium tuberculosis complex (MTBC) strains isolated from patients is an important aspect of TB control ...the drug sensitivity of MTBC isolates in South ...
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Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity
... residue is an important determinant of Hsp90 ATPase activity and drug sensitivity; T22 phosphorylation affects Hsp90 chaperone function and alters its sensitivity to Hsp90 inhibitors.. F[r] ...
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Study of drug sensitivity profile of patients with throat infections in lower Himalayan region
... This prospective study aimed at studying the infective profile of patients with throat infections and to study the drug sensitivity profile in these patients in lower Himalayan population. A total of 100 ...
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Original Article Spectrum of Bacterial Conjunctivitis and Their Drug Sensitivity (Efficacy) Pattern, in the Patients Attending in Tertiary Care Hospital at Muzaffarpur, Bihar
... Present study was conducted in the Department of Pharmacology, Sri Krishna Medical College, muzaffarpur with the help of Department of Ophthalmology and Department of Microbiology, during the period of October 2017 to ...
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Integrating heterogeneous drug sensitivity data from cancer pharmacogenomic studies
... attractive drug sensitivity metric, as it can be calculated for any dose response ...the drug into a single measure, and has been shown to be a robust metric for comparing a single drug across ...
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Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells.
... (e.g., drug or pathogen resistance 1–3,5 ) or via a suitable reporter 6 , although a screen for essential genes has been recently published 7 ...for drug sensitivity ...
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In silico modeling predicts drug sensitivity of patient derived cancer cells
... predict drug sensitivity in patient-derived GBM cell lines, we created simulation avatars (in silico profiles) for each cell line as illustrated in Figure ...
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Does the drug sensitivity of malaria parasites depend on their virulence?
... sub-optimal drug levels can facil- itate the evolution of classical drug resistance, where resistant parasites survive drug treatment through well- studied mechanisms, such as target-site mutations ...
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Functions and regulation of Hdmx and post-translational modifications in drug sensitivity and cancer.
... We have found that the treatment of several types of cells with Leptomycin B, which blocks nuclear export of proteins containing a Rev-like nuclear export signal, strongly increases al[r] ...
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Culture adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers
... There are currently six species of the genus Plasmodium known to infect humans: Plasmodium falciparum , Plas- modium vivax , Plasmodium ovale curtisi , Plasmodium ovale wallikeri , Plasmodium malariae and Plasmodium ...
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Article Bioinformatic Analysis for the Validation of Novel Biomarkers for Cancer Diagnosis and Drug Sensitivity
... individualised marker for defining the measurement of response (Toole et al 2007). Chemoresponse can be analysed by tumour microenvironment and tumour cell characteristics which includes gene expression levels, presence ...
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