Drugs and Compounds
Synthesis of cysteine-reactive compounds as drugs or pharmacological tools
... drug candidates, are good examples of the pharmacological exploitability of this kind of covalent modifier. New specific cysteine reactive covalent inhibitors for Epidermal Growth Factor Receptor Tyrosine Kinase domain ...
203
Antiangiogenic compounds: well-established drugs versus emerging natural molecules
... antiangiogenic drugs have been developed, and bevacizumab was the first one to be used in therapies applied in vivo to tumor ...these drugs, the development of new treatments is becoming highly ...bioactive ...
20
Pharmacokinetic Studies of some selected isolated compounds of Herbal Drugs in various Dosage Forms
... isolated compounds of herbal drugs are needed in order to safe use of the ...isolated compounds will reveal the present scenario in the field of herbal drug development, formulation and evaluation ...
287
Identification of Natural Compounds as Possible Anti Allergic Drugs using Molecular Docking Analysis
... natural compounds for search of ideal candidates by virtual screening methods using computational analysis reduces side effects, cost and time in drug ...most drugs at the clinical ...natural ...
7
Computational drugs repositioning identifies inhibitors of oncogenic PI3K/AKT/P70S6K-dependent pathways among FDA- approved compounds
... The discovery of inhibitors for oncogenic signalling pathways remains a key focus in modern oncology, based on personalized and targeted therapeutics. Computational drug repurposing via the analysis of FDA-approved drug ...
16
In silico Molecular Docking of Lavandula Angustifolia Mill’s compounds along with a number of antianxiety Drugs with GABAA receptor for reduce stress
... plants compounds concomitant Diazepam, Amobarbital and Phenobarbital as ligand and GABAA protein as ...Mill compounds ligands are safer and milder with fewer or no side effects than the drugs ...
6
“In Silico Identification of Natural Drugs from the Compounds of Phyllanthus urinaria Lin.” by Parameshwaran R, Shanthi R, Anbazhagan S, India.
... bioactive compounds to formulate effective drugs comparable to that of paclitaxel and doxorubicin, responsible for the inhibition of the target enzymes, causing ...bioactive compounds such as gallic ...
5
<p>Pharmacokinetic studies of nanoparticles as a delivery system for conventional drugs and herb-derived compounds for cancer therapy: a systematic review</p>
... anticancer drugs have limited their clinical ...conventional drugs and herb-derived compounds for cancer ...chemotherapeutic drugs loaded into nanoparticles were ...herb-derived ...
19
Study of novel natural compounds as potential drugs in the treatment of acute leukemias
... botanical drugs as a new anticancer strategy In the last years, the anticancer therapy strategy has been focused on the selective inhibition of key targets of cancer ...anticancer drugs used in therapy were ...
113
Voltammetric, Potentiality and Thermodynamic Studies of Some Rhodanine Sulfa Drugs Azo Compounds in Aqueous Solutions
... azo compounds in Britton- Robinson universal buffers containing 40 % (v/v) ethanol was investigated at the mercury electrode using dc-polarography, cyclic voltammetry and controlled potential ...azo ...
10
Phenolic compounds as antioxidants and chemopreventive drugs from Streptomyces cellulosae strain TES17 isolated from rhizosphere of Camellia sinensis
... phenolic compounds (both phenolic acids and flavonoids) made a significant contribution to the antioxidant potential of Streptomyces ...phenolic compounds in the TES17 ex- tract was done using HPLC analysis ...
15
The Biology and Regulation of Activating Transcription Factor 3 (ATF3) by Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Dietary Compounds with Chemopreventive Activity.
... chemopreventive compounds, we hypothesized that its biological activity may be related to ...of compounds with anti- invasive properties indicating it is associated with the inhibition of invasion thereby ...
203
Toward antituberculosis drugs: in silico screening of synthetic compounds against <em>Mycobacterium tuberculosis</em> L,D-transpeptidase 2
... drug compounds initially screened for a certain disease, only a few make it to clinical trials, and even after that, ,10% of those compounds from clinical trials success- fully get the final ...drug ...
11
Are the physicochemical properties of antibacterial compounds really different from other drugs?
... antibacterial drugs do have a more polar distribution, with a lower median calculated logP, elevated donor and acceptor counts and higher TPSA (compare the MAD and MOD rows of Table ...research compounds ...
9
Compounds from natural sources for new diagnostics and drugs against biofilm infections
... b P<0.001 versus infected subjects (Kruskal-Wallis test). Table 2. Comparison of titers of IgM antibodies against SSPA, expressed as ELISA units, in sera from subjects with an ongoing staphylococcal late-onset ...
25
Compounds from Natural Sources for New Diagnostics and Drugs against Biofilm Infections
... b P<0.001 versus infected subjects (Kruskal-Wallis test). Table 2. Comparison of titers of IgM antibodies against SSPA, expressed as ELISA units, in sera from subjects with an ongoing staphylococcal late-onset ...
25
Determination of Potential Compounds of Stevia Leaves (Stevia rebaudiana Bertoni) Against DPP4 as Candidates for Antidiabetic Drugs
... synthetic drugs, a biochemical compound can also be used for diabetes therapy, one of which is stevia ...select compounds contained in stevia leaves based on their interaction with DPP4 in ...potential ...
8
Reinforcement of Condensation Reaction using DCCI to Synthesis New Compounds Derived from Phthalyl Dl Leucine and Sulfa Drugs
... New compounds derived from N-phthalyl DL-leucine as amino acid derivative and some kinds of sulfa drugs like sulfanilamide, sulfaisoxazole, sulfamethaxzole, sulfadiazine, sulfathaizole, sulfapyridine and ...
10
The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti- microtubule drugs
... quinone-containing compounds, vincristine, nanaomycin Received: June 06, 2016 Accepted: September 28, 2016 Published: October 13, 2016 ABSTRACT BET bromodomain inhibitors are very promising novel anticancer ...
16
CEMTDD: The database for elucidating the relationships among herbs, compounds, targets and related diseases for Chinese ethnic minority traditional drugs
... traditional drugs while popularizes their information about research progresses and medication of ethnic traditional ...traditional drugs have also be recognized and utilized as traditional Chinese ...
10