Duchenne Muscular Dystrophy (DMD)
Clinical potential of ataluren in the treatment of Duchenne muscular dystrophy
... Abstract: Duchenne muscular dystrophy (DMD) is an autosomal dominant, X-linked neuromuscular disorder caused by mutations in dystrophin, one of the largest genes known to ...
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The golden retriever model of Duchenne muscular dystrophy
... Duchenne muscular dystrophy (DMD) is an X-linked disease caused by mutations in the DMD gene and loss of the protein ...retriever muscular dystrophy (GRMD) dog, have played a key role ...
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Clinical utility of serum biomarkers in Duchenne muscular dystrophy
... Duchenne muscular dystrophy (DMD) is a severe form of myopathy that affects 1 in 5000–20,000 male births worldwide [1, 2]. It is due to frame shift mutations in the X-linked dystrophin gene ...
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Duchenne muscular dystrophy (DMD) detail study
... Duchenne Muscular Dystrophy (DMD) is a highly severe type among all of inherited muscular ...hereditary muscular disease without any bias in terms of race or ...
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Challenges to oligonucleotides-based therapeutics for Duchenne muscular dystrophy
... therapy Duchenne muscular dystrophy (DMD) is a lethal X-linked progressive muscle-wasting disease caused by mutations, typically large deletions in the DMD gene, the largest gene in the human genome ...
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Psychosocial Management of the Patient With Duchenne Muscular Dystrophy
... In this article, we outline a comprehensive plan for the psychosocial management of patients with Duchenne muscular dystrophy (DMD) across the life span. In 2010, the Centers for Disease Control and ...
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Recent advances in Duchenne muscular dystrophy
... Abstract: Duchenne muscular dystrophy (DMD), an allelic X-linked progressive muscle- wasting disease, is one of the most common single-gene disorders in the developed ...
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Left ventricular T2 distribution in Duchenne Muscular Dystrophy
... Duchenne Muscular Dystrophy (DMD), a lethal X- linked skeletal and cardiac myopathy, affects 1/3500 males [1]. DMD is caused by mutations in the dystro- phin gene resulting in greatly reduced or ...
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Rehabilitation Management of the Patient With Duchenne Muscular Dystrophy
... of Duchenne muscular dystrophy (DMD) continues to lead to improved physical and functional status, allowing increasingly successful transitions to independence and self-actualization in ...
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An Introduction to the Duchenne Muscular Dystrophy Care Considerations
... of Duchenne muscular dystrophy, part 1: diagnosis, and neuromuscular, rehabilitation, endocrine, and gastrointestinal and nutritional management [published correction appears in Lancet ...
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Obesity and Endocrine Management of the Patient With Duchenne Muscular Dystrophy
... Duchenne muscular dystrophy (DMD) is associated with an increased risk of endocrine complications due to the effects of prolonged glucocorticoid therapy as well as progressive muscle ...
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Decreased Gait and Function in Duchenne Muscular Dystrophy
... Duchenne muscular dystrophy (DMD) is a genetic disorder linked to chromosome Xp21, due to absence of dystrophin ...of muscular dystrophies were ...
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Fatigue in Children and Adolescents with Duchenne Muscular Dystrophy
... To our knowledge, this is the first study to describe fatigue in children and adolescents with Duchenne muscular dystrophy (DMD), from the perspective of patients and their parents. Additionally, we ...
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Nutritional and Gastrointestinal Management of the Patient With Duchenne Muscular Dystrophy
... Advances in treatment and multidisciplinary management have resulted in improved survival of individuals with Duchenne muscular dystrophy (DMD). Updated DMD treatment recommendations as found in the ...
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Vascular-targeted therapies for Duchenne muscular dystrophy
... Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy and an X-linked recessive, progressive muscle wasting disease caused by the absence of a functional dystrophin ...
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Orthopedic and Surgical Management of the Patient With Duchenne Muscular Dystrophy
... Duchenne muscular dystrophy (DMD). In addition to progressive muscle weakness and loss of function, patients may develop joint contractures, scoliosis, and osteoporosis, causing fractures; all of ...
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Biomarkers of Duchenne muscular dystrophy: current findings
... as Duchenne muscular dystrophy, this endeavor has created a wealth of knowledge that, if effectively exploited, will benefit affected individuals, with respect to health care, therapy, improved ...
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Current and emerging treatment strategies for Duchenne muscular dystrophy
... Abstract: Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy in childhood. It is caused by mutations of the DMD gene, leading to progressive muscle ...
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A Transition Toolkit for Duchenne Muscular Dystrophy
... The care of individuals with Duchenne muscular dystrophy (DMD) now extends into adulthood. Childhood to adulthood transition planning is an important aspect of care, affecting health outcomes as well ...
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Computer task performance by subjects with Duchenne muscular dystrophy
... Aims: Two specific objectives were established to quantify computer task performance among people with Duchenne muscular dystrophy (DMD). First, we compared simple computational task performance ...
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