Dynein Light Chain
Functional Evidence of the Involvement of the Dynein Light Chain DYNLRB2 in Murine Leukemia Virus Infection
... FIG 3 Cytoplasmic dynein light chain DYNLRB2 is required for MLV infection. (A) DYNLRB1 and DYNLRB2 mRNA levels in cells engineered by DYNLRB1 or DYNLRB2 KD were determined by quantitative PCR. The ...
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Dynein light chain DLC 1 promotes localization and function of the PUF protein FBF 2 in germline progenitor cells
... We next performed a genetic screen to identify potential FBF-2 co- regulators inactivation of which causes synthetic enhancement of sterility in an fbf-1 loss-of-function [abbreviated as fbf-1(lf )] background, compared ...
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Extensive Attenuation of Rabies Virus by Simultaneously Modifying the Dynein Light Chain Binding Site in the P Protein and Replacing Arg333 in the G Protein
... infected in duplicate at a multiplicity of infection (MOI) of 10 with the various recombinant viruses. After 2 h of incubation at 37°C, the inoculum was removed, and the cells were rinsed three times with ...
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Human Immunodeficiency Virus Type 1 Employs the Cellular Dynein Light Chain 1 Protein for Reverse Transcription through Interaction with Its Integrase Protein
... as dynein light chain 1 (DYNLL1, LC8, DLC1), dynein light chain Tctex-type 1 (DYNLT1), and p150 Glued have been implicated in cargo recruitment to the dynein complex ...
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A Dynein Light Chain 1 Binding Motif in Rabies Virus Polymerase L Protein Plays a Role in Microtubule Reorganization and Viral Primary Transcription
... Rabies virus (RABV) polymerase L together with phosphoprotein P forms the PL polymerase complex that is essential for repli- cation and transcription. However, its exact mechanism of action, interactions with cellular ...
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Structure-Function Analysis of Dynein Light Chain 1 Identifies Viable Motility Mutants in Bloodstream-Form Trypanosoma brucei
... The flagellum of Trypanosoma brucei is an essential and multifunctional organelle that is receiving increasing attention as a potential drug target and as a system for studying flagellum biology. RNA interference (RNAi) ...
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<p>Effects of dynein light chain Tctex-type 3 on the biological behavior of ovarian cancer</p>
... of dynein light chain roadblock-type 1 (DYNLRB1) decreased the paracrine effect of colon cancer cell secretory factors in conditioned medium and fi broblast coculture, the invasion and migration of ...
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Interaction of the Rabies Virus P Protein with the LC8 Dynein Light Chain
... One quarter of the clones were analyzed further after elimi- nation of false positives, and 130 clones were partially se- quenced. Homology searches were performed at the National Center for Biotechnology Information ...
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The Novel Zinc Finger Protein dASCIZ Regulates Mitosis in Drosophila via an Essential Role in Dynein Light-Chain Expression
... of dynein light chain (DYNLL1/LC8), but its functions in other species including invertebrates are largely ...impaired dynein motor ...DYNLL/LC8-type dynein light chain ...
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Ebolavirus VP35 Interacts with the Cytoplasmic Dynein Light Chain 8
... 8-kDa dynein light chain ...cytoplasmic dynein motor complex involved in the microtubule-associated intracellular transport system (29, 33, ...
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Dynein light chain binding to a 3′ untranslated sequence mediates parathyroid hormone mRNA association with microtubules
... 40 minutes at 4°C. The acceleration was chosen to allow precipitation of organelles and cytoskeletal struc- tures without precipitation of soluble elements such as tubulin in either its monomeric or ring structure. The ...
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Atmin is a transcriptional regulator of both lung morphogenesis and ciliogenesis
... target dynein light chain LC8-type 1 (DYNLL1) are required for normal lung morphogenesis and ...cytoplasmic dynein 2 intermediate chain that also localised to the ...cytoplasmic ...
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Calcium sensors of ciliary outer arm dynein: functions and phylogenetic considerations for eukaryotic evolution
... heavy chain of two-headed outer arm dynein in a Ca 2+ -dependent manner and regulates ‘ asymmetric ’ wave propagation at high concentrations of Ca 2+ ...arm dynein in Chlamydomonas reinhardtii, the ...
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The Carboxyl Terminus of Tegument Protein pUL21 Contributes to Pseudorabies Virus Neuroinvasion
... cytoplasmic dynein motor transports cargo to the minus end of microtubules ...The dynein complex is involved in the transport of herpesvirus in the early stage of infection ...two light-intermediate ...
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Novel 44-Kilodalton Subunit of Axonemal Dynein Conserved from Chlamydomonas to Mammals
... crude dynein extracts us- ing the anti-p44 antibody and protein A-conjugated ...a dynein heavy chain, as detected by gel patterns and specific antibodies ...the dynein d heavy chain ...
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spn F encodes a novel protein that affects oocyte patterning and bristle morphology in Drosophila
... In addition to the effects on the oocyte, we have found that spn-F affects the development of the bristles. The highly elongated bristles of Drosophila have proven to be a valuable model system for studying cellular ...
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A new mode of mitochondrial transport and polarized sorting regulated by Dynein, Milton and Miro
... and dynein motor proteins (van Spronsen et ...that dynein serves as the primary motor for mitochondrial bristle transport, and that milton and miro are not required for mitochondrial transport per se but ...
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African Swine Fever Virus Protein p54 Interacts with the Microtubular Motor Complex through Direct Binding to Light-Chain Dynein
... cytoplasmic dynein and kinesin are believed to be responsible for organelle movement in opposite directions along microtubules ...mic dynein mediates the return of vesicles to the microtubular organizing ...
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Primary cerebral low-grade B-cell lymphoma, monoclonal immunoglobulin deposition disease, cerebral light chain deposition disease and “aggregoma”: an update on classification and diagnosis
... monotypic light and/or heavy chain proteins in various tissues and ...(Ig) light and/or heavy chain producing B-cells ...the light chain-derived amyloidosis (AL) subgroup, ...
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Development and characterization of polyclonal antibody against human kappa light chain in rabbit
... kappa light chain are used to diagnose diseases producing free light ...lambda light chains are products of immunoglobulin synthesis and released into the circulation in minor amounts such as ...
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