dynein light intermediate chain
Atmin is a transcriptional regulator of both lung morphogenesis and ciliogenesis
... target dynein light chain LC8-type 1 (DYNLL1) are required for normal lung morphogenesis and ...cytoplasmic dynein 2 intermediate chain that also localised to the ...cytoplasmic ...
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HIV-1 Engages a Dynein-Dynactin-BICD2 Complex for Infection and Transport to the Nucleus
... heavy chain and dynactin component depletion inhibits HIV-1 infec- ...that dynein plays a role in HIV-1 infection and intracellular transit (5, ...of dynein and the associated dynactin complex ...
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Interaction of the Rabies Virus P Protein with the LC8 Dynein Light Chain
... a light chain component of cytosolic and flagellar dynein, which forms the microtubule (MT)-associated motor protein complexes involved in the minus end-directed move- ment of chromosomes and ...
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The Herpes Simplex Virus 1 UL34 Protein Interacts with a Cytoplasmic Dynein Intermediate Chain and Targets Nuclear Membrane
... Cytoplasmic dynein is one of the major motor proteins involved in intracellular transport and is the only known ret- rograde motor in interphase cells ...production, light intermediate chains and ...
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Functional Evidence of the Involvement of the Dynein Light Chain DYNLRB2 in Murine Leukemia Virus Infection
... with dynein and dynein regulators (16); specifically, the dynein intermediate chain DYNC1I2 is required for MLV ...The dynein intermediate chain is not only ...
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The Carboxyl Terminus of Tegument Protein pUL21 Contributes to Pseudorabies Virus Neuroinvasion
... cytoplasmic dynein motor transports cargo to the minus end of microtubules ...The dynein complex is involved in the transport of herpesvirus in the early stage of infection ...two intermediate ...
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The Gene for the Intermediate Chain Subunit of Cytoplasmic Dynein Is Essential in Drosophila
... heavy chain and level of dynein intermediate chain available for cargo kinesin light chain genes (Hurd and Saxton 1996; binding below a threshold required for normal eye de- ...
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Dynein light chain binding to a 3′ untranslated sequence mediates parathyroid hormone mRNA association with microtubules
... 40 minutes at 4°C. The acceleration was chosen to allow precipitation of organelles and cytoskeletal struc- tures without precipitation of soluble elements such as tubulin in either its monomeric or ring structure. The ...
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Targeted deletion of mouse dynein 2 light intermediate chain disrupts formation of the body axes
... example, human and mouse share 87% identity and 92% similarity of amino acid charges (Table 4.1 and Figure 4.2). In addition, search results revealed a further two putative homologues from C. elegans and D. melanogaster ...
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Dynein light chain DLC 1 promotes localization and function of the PUF protein FBF 2 in germline progenitor cells
... the dynein motor complex (Pfister et al., 1982); however, extensive dynein- independent functions of DLC-1 have also been identified (Herzig et ...the dynein motor complex contribute to FBF-2 ...
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Novel 44-Kilodalton Subunit of Axonemal Dynein Conserved from Chlamydomonas to Mammals
... kinesin light chain ...between dynein d and another protein, pos- sibly participating in dynein ...or dynein d heavy chains that can be present in very small amounts in the ...where ...
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The Novel Zinc Finger Protein dASCIZ Regulates Mitosis in Drosophila via an Essential Role in Dynein Light-Chain Expression
... for dynein light-chain DYNLL1 was the most strongly downregulated transcript (10-fold) in mouse Asciz knockout cells, and similar DYNLL1 reductions were observed in ASCIZ- deficient human and chicken ...
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Structure-Function Analysis of Dynein Light Chain 1 Identifies Viable Motility Mutants in Bloodstream-Form Trypanosoma brucei
... FIG. 2. HA-tagged LC1 rescues the LC1 RNAi phenotype in procyclic cells. (A) Transmission electron microscopy analysis of flagellum ultrastructure in uninduced control cells (control), LC1 UTR RNAi cells (RNAi ⫹ Tet), ...
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Human Immunodeficiency Virus Type 1 Employs the Cellular Dynein Light Chain 1 Protein for Reverse Transcription through Interaction with Its Integrase Protein
... of dynein function by KD of dynein heavy chain (DYNC1H1) or the disruption of the intact MT filaments in cells by nocodazole treatment delayed the un- coating process during HIV-1 infection (20, ...
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Outer Dynein Arm Light Chain 1 Is Essential for Controlling the Ciliary Response to Cyclic AMP in Paramecium tetraurelia
... outer dynein arms were decreased to some extent ...outer dynein arm may be essential to produce a high ciliary beat ...outer dynein arm com- ponents, will be required to clarify the mechanisms ...
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African Swine Fever Virus Protein p54 Interacts with the Microtubular Motor Complex through Direct Binding to Light-Chain Dynein
... within dynein complexes directly contact the ...the dynein-dynactin complex results in inhibition of ...with dynein dominant-negative mutant were not infected, and no simultaneous expression of both ...
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Molecular genetic analysis of primary ciliary dyskinesia
... the dynein motor domain is dramatically different from that of kinesin or ...Each dynein heavy chain appears to have several globular elements that surround a central void and at least one prominent ...
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A vascular endothelial growth factor receptor gene variant is associated with susceptibility to acute respiratory distress syndrome
... Methods: We first performed a prioritization of candidate genes by integrating our own genomic data from a transcriptomic study in an animal model of ARDS and from the only published genome-wide association study of ARDS ...
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A new mode of mitochondrial transport and polarized sorting regulated by Dynein, Milton and Miro
... and dynein motor proteins (van Spronsen et ...that dynein serves as the primary motor for mitochondrial bristle transport, and that milton and miro are not required for mitochondrial transport per se but ...
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Development and characterization of polyclonal antibody against human kappa light chain in rabbit
... could be beneficial for many types of detection methods and shows the high quality of the product. The SDS-PAGE analysis exhibited the protein with approximately 25.00 kDa and the titer of direct ELISA was 1:16000. We ...
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