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early life adversity

The impact of early life adversity on later life health

The impact of early life adversity on later life health

... the life course theoretical perspective, the present research draws from Ferraro and colleagues’ (2009) middle-range Cumulative Inequality Theory in accounting for the effects of early life ...occur ...

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Interpersonal violence, early life adversity, and suicidal behavior in hypersexual men

Interpersonal violence, early life adversity, and suicidal behavior in hypersexual men

... childhood adversity, interpersonal violence, and suicidal behavior in hypersexual disorder ...assessing early life adversity and interpersonal violence in childhood and in adult ...of ...

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The developmental origins of chronic physical aggression: biological pathways triggered by early life adversity

The developmental origins of chronic physical aggression: biological pathways triggered by early life adversity

... to early-life adversity is genome- and system-wide, and targets mostly tissue-specific functions in both the brain and the periphery, further supporting the use of peripheral immune cells in the ...

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The 5-HTTLPR genotype, early life adversity and cortisol responsivity to psychosocial stress in women

The 5-HTTLPR genotype, early life adversity and cortisol responsivity to psychosocial stress in women

... of early life ...of early adversities, most notably regarding the nature of the event and the neurodevelopmental period when the event occurred, might be a source of inconsistent ...in early ...

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Early-life adversity, later-life mental health, and resilience resources: a longitudinal population-based birth cohort analysis.

Early-life adversity, later-life mental health, and resilience resources: a longitudinal population-based birth cohort analysis.

... psychosocial adversity and poorer mental health outcomes is well documented, (Green et ...and early-life adversity is associated with lower risk of later-life mental health, whereas ...

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Sex-specific impact of early-life adversity on chronic pain: a large population-based study in Japan

Sex-specific impact of early-life adversity on chronic pain: a large population-based study in Japan

... of early-life adversity on chronic pain ranging from 0 (not at all) to 4 (extremely), regarding each of seven symptoms during the past 7 days: faintness or diz- ziness, pain in the heart or chest, ...

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Early life adversity is associated with a smaller hippocampus in male but not female depressed in patients: a case–control study

Early life adversity is associated with a smaller hippocampus in male but not female depressed in patients: a case–control study

... If they could be replicated in further studies, our re- sults may have several implications. Generally speaking, it would be useful to pay more attention to ELA in boys and men, their assessment and potential impact on ...

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An investigation into stress response axis, serotonin system and adaptive immunity in depression : a focus on early life adversity and epigenetic mechanisms

An investigation into stress response axis, serotonin system and adaptive immunity in depression : a focus on early life adversity and epigenetic mechanisms

... Although many studies published to date indicate a role of hypermethylation of the NR3C1 gene in depression, particularly when patients have experienced early life adversity, the findings are not ...

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Early-life adversity and long-term neurobehavioral outcomes: epigenome as a bridge?

Early-life adversity and long-term neurobehavioral outcomes: epigenome as a bridge?

... in early life, both pre- and postnatal, can lead to neuroendocrine perturbations, including hypothalamic-pituitary-adrenal axis dysregulation and inflammation persisting up to ...adverse ...

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The Lasting Damage to Mortality of Early-Life Adversity: Evidence from the English Famine of the late 1720s

The Lasting Damage to Mortality of Early-Life Adversity: Evidence from the English Famine of the late 1720s

... The mechanism by which disease experienced early in life affect the waiting time to the onset of illness are still unclear. But scholars seem to agree that exposure to undernourishment during periods when ...

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Early life adversity programs long term cytokine and microglia expression within the HPA axis in female Japanese quail

Early life adversity programs long term cytokine and microglia expression within the HPA axis in female Japanese quail

... ABSTRACT Stress exposure during prenatal and postnatal development can have persistent and often dysfunctional effects on several physiological systems, including immune function, affecting the ability to combat ...

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History of early life adversity is associated with increased food addiction and sex-specific alterations in reward network connectivity in obesity.

History of early life adversity is associated with increased food addiction and sex-specific alterations in reward network connectivity in obesity.

... tiate early during CNS development, with sex differences in the serotonergic system of the rat brain established as early as the second postnatal week, likely mediated by in- tracellular oestrogen receptors ...

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The role of FKBP5 genetics and epigenetics in mediating the effects of early life adversity on emotional processing brain regions in major depressive disorder

The role of FKBP5 genetics and epigenetics in mediating the effects of early life adversity on emotional processing brain regions in major depressive disorder

... interaction between a high-risk SNP of the FKBP 5 gene, its epigenetic changes, chronic environmental stress in the form of childhood mal- treatment and functional as well as structural [r] ...

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A cross- sectional study of stress biomarkers and their associations with post-trauma complaints, and how those associations are moderated by early life adversity

A cross- sectional study of stress biomarkers and their associations with post-trauma complaints, and how those associations are moderated by early life adversity

... of early identification and intervention in those people with acute pain that are likely to transition into a state of chronicity, attempting to prevent the onset of chronic pain before it emerges and becomes ...

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The Lasting Legacy of Childhood Adversity for Disease Risk In Later Life

The Lasting Legacy of Childhood Adversity for Disease Risk In Later Life

... childhood adversity and later dis- ease simply reflects the correlation of early life adversity with adult socioeconomic ...to adversity during childhood represents residual con- ...

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Epigenetic Embedding of Early Adversity and Developmental Risk

Epigenetic Embedding of Early Adversity and Developmental Risk

... heightened, adversity-related epigenetic changes in ...20 Early adolescents who had been physically abused showed increased epigenetic marking of the GR gene compared to peer ...

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The biological embedding of early-life socioeconomic status and family adversity in children's genome-wide DNA methylation.

The biological embedding of early-life socioeconomic status and family adversity in children's genome-wide DNA methylation.

... and adversity compared with prior studies that have relied on a single item or a dichotomized item, our use of SES and adversity measures collected in childhood to prospectively predict later biological ...

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Like Father, like Child: Early Life Family Adversity and Children's Bullying Behaviors in Elementary School.

Like Father, like Child: Early Life Family Adversity and Children's Bullying Behaviors in Elementary School.

... For several reasons, we hypothesized that adverse family char- acteristics of the father predict child bullying behavior inde- pendently of maternal family adversity. First, the manifesta- tion of fathers’ ...

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Exploring The Link Between Early Adversity And Behavioral Health

Exploring The Link Between Early Adversity And Behavioral Health

... between Early Adversity and Behavioral Health Background/Rationale Adverse childhood experiences (ACE) and their lasting sequelae are a significant public health ...

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The Lifelong Effects of Early Childhood Adversity and Toxic Stress

The Lifelong Effects of Early Childhood Adversity and Toxic Stress

... the life prospects of children and to strengthen the social and economic fabric of ...how early experiences and envi- ronmental in fl uences can leave a lasting signature on the genetic predispositions that ...

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