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EC, endothelial cells

Switched at birth: a new family for PECAM 1

Switched at birth: a new family for PECAM 1

... on endothelial cells, where up to one million molecules concentrate at intracellular junctions shortly after cell–cell ...glycoprotein-1; EC, endothelial cells; Epi, epithelial ...

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Interaction of monocytes with cocultures of human aortic wall cells involves interleukins 1 and 6 with marked increases in connexin43 message

Interaction of monocytes with cocultures of human aortic wall cells involves interleukins 1 and 6 with marked increases in connexin43 message

... EC/COL, endothelial cells grown on a layer of collagen on a filter; EC/COL/SMC, a multilayer of smooth muscle cells grown on a filter, covered with a layer of collagen, with an endotheli[r] ...

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Extracellular Superoxide Dismutase Overexpression Can Reverse the Course of Hypoxia-Induced Pulmonary Hypertension

Extracellular Superoxide Dismutase Overexpression Can Reverse the Course of Hypoxia-Induced Pulmonary Hypertension

... microvascular endothelial cells showed that cells transfected with EC-SOD had signifi- cantly less accumulation of xanthine oxidase and reactive oxygen species than nontransfected cells ...

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An Active Learning Approach for Rapid Characterization of Endothelial Cells in Human Tumors

An Active Learning Approach for Rapid Characterization of Endothelial Cells in Human Tumors

... tumor endothelial cells (EC) and EC activation and survival signaling are the direct targets of these therapies, we sought to develop an automated platform for quantifying activity of critical ...

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Palmitate-Induced Apoptosis of Microvascular Endothelial Cells and Pericytes

Palmitate-Induced Apoptosis of Microvascular Endothelial Cells and Pericytes

... of cells, endothelial cells (EC) and ...co-cultured EC, thus providing a basis for understanding how diabetic retinopathy develops consequent to pericyte loss, the earliest ...

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Active roles of dysfunctional vascular endothelium in fibrosis and cancer

Active roles of dysfunctional vascular endothelium in fibrosis and cancer

... arterial endothelial cells were propa- gated and treated with recombinant human IL-1β ...thelial cells show upregulation of genes previously observed in other fibrotic systems, including COX-2, ...

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Blocking MHC class II on human endothelium mitigates acute rejection

Blocking MHC class II on human endothelium mitigates acute rejection

... graft cells stimulate this process. In human grafts, endothelial cells (EC) that line the vasculature of the organ are primary cellular targets of acute rejection responses (10, 13, ...human ...

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Combinatorial treatment of acute myocardial infarction using stem cells and their derived exosomes resulted in improved heart performance

Combinatorial treatment of acute myocardial infarction using stem cells and their derived exosomes resulted in improved heart performance

... progenitor cells (CPCs) with MSC-derived exosomes and then transplanted the pretreated CSCs into a rat MI ...from endothelial cells (EC-Exo) with CPCs into MI mice and demonstrated that CPCs ...

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Endothelial cells influence the osteogenic potential of bone marrow stromal cells

Endothelial cells influence the osteogenic potential of bone marrow stromal cells

... dependent and the other is Runx2 independent [25]. To investigate the possible reasons underlying the changes in ALP expression described above, the key transcription fac- tor Runx2 was tested by PCR. Within 5 days of ...

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Electron microscopic study of rheumatoid synovial vasculature  Intimate relationship between tall endothelium and lymphoid aggregation

Electron microscopic study of rheumatoid synovial vasculature Intimate relationship between tall endothelium and lymphoid aggregation

... the endothelial cells (EC) of postcapillary venules (PCV) and capillaries and the cellular composition of adjacent perivascular mononuclear cell infiltrates in rheumatoid (RA) synovial membrane has ...

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Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling

Celecoxib exerts protective effects in the vascular endothelium via COX-2-independent activation of AMPK-CREB-Nrf2 signalling

... Endothelial cells. Use of human EC was approved by Hammersmith Hospitals Research Ethics Committee (ref ...vein endothelial cells (HUVEC) were isolated by colla- genase Type II ...

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Inhibition of human endothelial cell proliferation in vitro and neovascularization in vivo by D penicillamine

Inhibition of human endothelial cell proliferation in vitro and neovascularization in vivo by D penicillamine

... To investigate the effects of D-penicillamine (D-Pen) on angiogenesis, we have studied the effects of this drug on in vitro proliferation of human endothelial cells (EC) and in vivo corneal ...

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Indirubin inhibits cell proliferation, migration, invasion and angiogenesis in tumor-derived endothelial cells

Indirubin inhibits cell proliferation, migration, invasion and angiogenesis in tumor-derived endothelial cells

... Total RNA was extracted from Td-EC and HUVEC using Trizol Reagent (Thermo Fisher Scientific), and cDNA was synthesized from total RNA using RevertAid First Strand cDNA Synthesis Kit (Thermo Fisher Scientific). The ...

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A Sensitive Method for Quantifying Cytomegalic Endothelial Cells in Peripheral Blood from Cytomegalovirus-Infected Patients

A Sensitive Method for Quantifying Cytomegalic Endothelial Cells in Peripheral Blood from Cytomegalovirus-Infected Patients

... think endothelial cells (EC) are ...that EC are important targets for virus, together with epithelial cells, fibroblasts, and smooth muscle cells ...

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Comparison of apoptosis in human primary pulmonary endothelial cells and a brain microvascular endothelial cell line co cultured with Plasmodium falciparum field isolates

Comparison of apoptosis in human primary pulmonary endothelial cells and a brain microvascular endothelial cell line co cultured with Plasmodium falciparum field isolates

... preferential EC apoptosis: half of the 16 apopto- genic isolates specifically targeted hCMEC/D3 cells, while only one specifically targeted HLEC, and seven targeted both cell ...brain EC apoptosis, ...

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Severe endothelial injury and subsequent repair in patients after successful cardiopulmonary resuscitation

Severe endothelial injury and subsequent repair in patients after successful cardiopulmonary resuscitation

... that endothelial damage could be the initial step in post-resuscitation dis- ease resulting in secondary inflammatory ...for endothelial damage might be hypoxia [30] or shear stress ...

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HMGA1 promotes breast cancer angiogenesis supporting the stability, nuclear localization and transcriptional activity of FOXM1

HMGA1 promotes breast cancer angiogenesis supporting the stability, nuclear localization and transcriptional activity of FOXM1

... cancer cells governs angiogenic processes of endothelial cells Gene Ontology (GO) analysis of our RNA-Seq data re- vealed that the proteins coded by HMGA1-differentially expressed genes are enriched ...

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Long space missions, gene therapy, and the vital role of magnesium: a three-pronged plan for the next 50 years

Long space missions, gene therapy, and the vital role of magnesium: a three-pronged plan for the next 50 years

... Although the entire body is in jeopardy during a space flight, obviously it would be absurd to suggest that for a very long mission, replacement of a large portion of the genome would be required. However, it is ...

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Endothelial progenitor cells in ischemic stroke: an exploration from hypothesis to therapy

Endothelial progenitor cells in ischemic stroke: an exploration from hypothesis to therapy

... of endothelial damage, as they may be responsible for increased ET-1 expression, which may further play a role in the pathophysiology of stroke and subsequent EPC mobilization ...

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Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: a laboratory study using an in vitro model

Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: a laboratory study using an in vitro model

... derived cells (HTR8/SVneo cell line), which were re- ported to share phenotypic and functional characteristics of EVT cells [17, ...HTR8/SVneo cells express HPA-1a epitope as part of αVβ3 integrin ...

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