ecdysone receptor (EcR)
Three calpains and ecdysone receptor in the land crab Gecarcinus lateralis: sequences, expression and effects of elevated ecdysteroid induced by eyestalk ablation
... Caenorhabditis elegans; domain IV was replaced by a unique ‘T domain’ sequence. It was expressed in most tissues, except eyestalk ganglia and Y-organ. The effects of elevated ecdysteroid, induced by eyestalk ablation, on ...
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The Insect Ecdysone Receptor is a Good Potential Target for RNAi-based Pest Control
... insect ecdysone receptor (EcR) is a good potential target for RNAi-based pest control in the brown planthopper Nilaparvata lugens, a serious insect pest of rice ...
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Drosophila CORL is required for Smad2 mediated activation of Ecdysone Receptor expression in the mushroom body
... lacking Ecdysone Receptor (EcR-B1) expression in MB ...I receptor upstream of Smad2) cannot stimulate EcR-B1 MB expression in Df(4)dCORL larvae, which demonstrates a formal requirement for CORL in ...
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The Ecdysone receptor controls the post critical weight switch to nutrition independent differentiation in Drosophila wing imaginal discs
... hormone ecdysone, we hypothesized that ecdysone signaling switches the larva to a nutrition-independent mode of development post-critical ...the Ecdysone receptor (EcR) selectively in the ...
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The Drosophila ecdysone receptor (EcR) Gene Is Required Maternally for Normal Oogenesis
... emerges Ecdysone signaling in Drosophila is controlled by a from the pupal case, ovarioles contain only previtello- heteromeric receptor composed of the EcR and USP genic (stages 1–7) egg chambers (see King ...
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Ecdysone signaling is required for proper organization and fluid secretion of stellate cells in the Malpighian tubules of Drosophila melanogaster
... of ecdysone, most of the larval tissues degenerate, while the imaginal cells differentiate and form adult specific ...by ecdysone during metamorphosis, we show that ecdysone signaling plays an ...
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Control in time and space: Tramtrack69 cooperates with Notch and Ecdysone to repress ectopic fate and shape changes during Drosophila egg chamber maturation
... Fig. 5. Expression of activated N, TTK69 and dominant-negative Ecdysone receptor causes defects in follicle cell shape and patterning. FLP-out clones (green/arrowheads) of UAS-N-CA, UAS-ttk69 or UAS-EcR-DN. ...
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Fine tuning of secondary arbor development: the effects of the ecdysone receptor on the adult neuronal lineages of the Drosophila thoracic CNS
... the ecdysone pathway, we investigated the role of ecdysone in the development of the adult-specific neuronal lineages using a dominant-negative construct of the ecdysone receptor ...the ...
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The Ecdysone inducible zinc finger transcription factor Crol regulates Wg transcription and cell cycle progression in Drosophila
... (20-hydroxy ecdysone) is a key steroid hormone in Drosophila, which has been predominantly studied for its role in the remodelling of larval tissues, a requirement for patterning of adult structures (Thummel, ...
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JNK signaling coordinates with ecdysone signaling to promote pruning of Drosophila sensory neuron dendrites
... by ecdysone receptor B1 (EcRB1) at early pupal stages, suggesting that ecdysone signaling provides temporal control of the regulation of dendrite pruning by JNK ...and Ecdysone signaling ...
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Dehydration triggers ecdysone-mediated recognition-protein priming and elevated anti-bacterial immune responses in Drosophila Malpighian tubule renal cells
... by ecdysone in the context of development and, as shown here, by ...use ecdysone to prime innate immune in- duction of AMPs in the renal organ in response to water-stress ...
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Estrogen receptor transcription and transactivation Estrogen receptor alpha and estrogen receptor beta: regulation by selective estrogen receptor modulators and importance in breast cancer
... estrogen receptor regulates transcription Although the DNA binding domains of ERα and ERβ are nearly identical, there is considerable documentation that these receptor subtypes differ markedly in their ...
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Oriental fruit moth phenology in North Carolina apples and ecdysone agonist activity on oriental fruit moth and codling moth.
... are ecdysone agonists that mimic the steroid 20-hydroxyecdysone, the molting hormone in insects (Dhadialla et ...of ecdysone from the prothoracic gland into the insect hemolymph (Evans ...of ecdysone ...
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receptor ligands
... [25] Epix Pharmaceuticals, Inc. October 29, 2007 press release; http://www.epixpharma.com [26] R. Nirogi, R. Kambhampati, A. Shinde, V. Kandikere, K. Mudigonda, G. Bhyrapuneni, P. Jayarajan, R. abraham, S. Mulla, V. ...
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Cortini, Roberto (2018): Analysis and modeling of the ecdysone response in Drosophila melanogaster. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... if ecdysone has not ligated [Schubiger et al., 2005]. This seems to hold also in S2 cells. After stimulation, EcR is suggested to be an activator, in particular in early time points, whereas in later time points ...
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Regulation of ecdysone biosynthesis in the tobacco hornworm, Manduca sexta: titre of the haemolymph stimulatory factor during the last larval instar
... This seeming contradiction — a low ecdysteroid titre in the presence of high levels of stimulatory factor - is apparently explained by the finding that prothoracic glands are not compete[r] ...
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The ecdysone-induced puffing cascade in Drosophila salivary glands: a Broad-Complex early gene regulates intermolt and late gene transcription.
... We provide evidence for this model at the transcrip- tional level by demonstrating that the expression of at least six downstream genes located in the 71E late puff [r] ...
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Soluble Receptor-Induced Retroviral Infection of Receptor-Deficient Cells
... that receptor binding triggers changes in virus that are functionally similar to the changes observed in EnvA fol- lowing Tva ...binding. Receptor binding induces conformational changes in poliovirus, ...
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Expression of functional toll like receptor 4 in estrogen receptor/progesterone receptor negative breast cancer
... Most studies of TLRs in breast cancer have been per- formed using the ER + cell line MCF-7 and the TN cell line MDA-MB-231 [5]. To our knowledge, a detailed comparison between ER + and TN cell lines or cancers has not ...
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MicroRNAs and Toll-like Receptor/Interleukin-1 Receptor Signaling
... translation repression resulted in avid scientific interest in miRNAs over the past decade. This research has led to findings that indicate miRNAs can regulate an array of cellular functions such as cellular apoptosis, ...
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