Enantiomeric excess
Two kinds of the smectic C subphases in a liquid crystal and their relative stability dependent on the enantiomeric excess as elucidated by the electric field induced birefringence experiment
... range and to foster theoretical understanding of the short- pitch helical structure by using a model recently proposed by Emelyanenko and Osipov based on the novel discrete flexo- electric polarization 关 40–42 兴 . ...
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Towards deracemization in the absence of grinding through crystal transformation, ripening, and racemization
... fast enantiomeric excess increase in the absence of grinding for aspartic ...induce enantiomeric enrichment in a similar manner 28,29,44 ...phase enantiomeric excess, even in the ...
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The effect of deep eutectic solvents on the asymmetric hydrolysis of styrene oxide by mung bean epoxide hydrolases
... Results: Adding deep eutectic solvents with hydrogen bond donor of acids to phosphate buffer resulted in an obvi‑ ous decrease in the optical purity of product; nevertheless, the relative slight change was observed by ...
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Ibuprofen Maltodextrin Interaction: Study of Enantiomeric Recognition and Complex Characterization
... NMR based methods, such as 1 H-NMR, have been used to evaluate enantiomeric recognition and to deter- mine the enantiomeric excess of chiral compounds. The development of new types of chiral ...
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Determination of Enantiomeric Composition of Substituted Tetrahydroisoquinolines Based on Derivatization with Menthyl Chloroformate
... ee (3) Symbols R, α and ee represent the resolution factor, selectivity factor and enantiomeric excess, respectively. Symbols t, w and c are retention time, peak width at the baseline and concentration of ...
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Scaling up temperature cycling-induced deracemization by suppressing nonstereoselective processes
... After the successful TCID on a small scale, TCID was tested in a 300 ml suspension (Medium scale setup M) using temperature profile TP1 (TP1-M) and a 1L suspension (large scale setup L) with temperature profile TP1 ...
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Chemoenzymatic Synthesis of Some Bioactive Compounds
... The enantiomeric excess has been obtained by chiral HPLC and the configurations were assigned by comparing the observed rotation data with the literature ...with enantiomeric excess ranging ...
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Stereo-selective oxidations of terpinolene by cytochrome P450 monooxygenases in the microsomal fraction of Cupressus lusitanica cultured cells
... Abstract We showed previously that in Cupressus lusi- tanica (Mexican cypress), the first two steps of terpinolene oxidation, beginning at hydroxylation at the aryl position and then forming epoxide at the double bond, ...
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Enantioselective Aldol Reactions and Michael Additions Using Proline Derivatives as Organocatalysts
... the enantiomeric excesses were very low except for catalyst ...the enantiomeric excess of the reaction was measured several times through- out the reaction, showing no significant variation in ...
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Organocatalyzed transformations of alpha,beta-unsaturated carbonyl compounds through iminium ion intermediates
... the enantiomeric excess values of the products is due to rapid hydrolysis of the iminium ion adducts (4) before they can undergo retro Diels–Alder reaction (Step ...
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UV/VIS Spectrometry with multivariate calibration as a new approach for the Chiral analysis of Fluoxetine
... Each enantiomer of the chiral drug has different pharmacokinetic, pharmacological and psychological properties. One enantiomer of a chiral molecule may be therapeutically active the other one may be inactive or may have ...
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Enantiomeric Analysis of Citalopram in Human Plasma by SPE and Chiral HPLC Method
... the enantiomeric resolution of citalopram on amylase column is governed by - interactions, hydrogen bondings, and dipole induced dipole interactions and ...
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METHOD DEVELOPMENT AND VALIDATION OF ZOLMITRIPTAN IN BULK AND TABLET DOSAGE FORM BY RP-HPLC
... Several studies for the estimation of the Zolmitriptan drug using various techniques have been carried out, some of them being ; dose proportionality and tolerability of single and repeat doses of a nasal spray ...
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Enantiomeric analysis of monoterpenes in Oba-kuromozi (Lindera umbellata var. membranacea)
... We clarified the terpenoid composition of the different tissues of Oba-kuromozi and showed that there was a dif- ference in the composition of the extracts of these tissues. The leaf extract had much greater amounts of ...
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DETERMINATION OF ENANTIOMERIC IMPURITY IN BESIFLOXACIN HYDROCHLORIDE BY CHIRAL HIGHPERFORMANCE LIQUID CHROMATOGRAPHY
... of Enantiomeric impurity (Impurity-A) in Besifloxacin Hydrochloride by using amylose tris (3,5- dichlorophenylcarbamate) as stationary phase with column dimension of ...of enantiomeric impurity in ...
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Peptide dendrimers as “lead compounds” for the treatment of chronic lung infections by <em>Pseudomonas aeruginosa</em> in cystic fibrosis patients: in vitro and in vivo studies
... Aim: In the present work, the potential of the D-enantiomeric dendrimers dG3KL and dTNS18 was evaluated in relation to tobramycin (Tob), for the development of novel antibacterials to treat Pseudomonas aeruginosa ...
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A Validated Stability Indicating And Enantiospecific Upc2 Sfc-Ms Method For Separation And Quantification Of (S)- Isomer In Tenofovir Disoproxil Fumarate In Presence Of Its Degradation Impurities
... used in the treatment of HIV pollution & chronic hepatitis B infection in combination with other antiretroviral (3). Tenofovir consumes in vitro motion beside H.I.V-1, H.I.V-2 and humanoid hepatitis B virus (4–7) ...
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Ultrasonic Study of Excess thermoacoustic Parameters in Binary Mixtures of Propylene Glycol and Hexanol
... The excess thermodynamic functions are sensitively dependent not only on the differences in intermolecular forces, but also on the differences in the size of the ...these excess values with temperatures and ...
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Optical properties of planar chiral meta materials
... enantiomeric structures were always of the same amplitude, but of strictly opposite sign. We have also compared the polarization azimuth rotation for the same samples for positive and negative incident angles, ± β ...
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Liquid Chromatographic method for the Determination of Enantiomeric Purity of Levobetaxolol by Chiral Chromatography
... A simple precise, accurate Normal phase High performance liquid chromatographic method has been developed for the Determination Of Enantiomeric Purity of Levobetaxolol by Chiral Chromatography. In this method a ...
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