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Endocannabinoid System

Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise

Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise

... There are limited data regarding the effects of weigh loss and/or exercise training on adipose tissue endocan- nabinoid system in obesity. In two previous studies, weight loss by 5% did not change abdominal ...

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Regulation of Adipose Tissue Metabolism by the Endocannabinoid System

Regulation of Adipose Tissue Metabolism by the Endocannabinoid System

... the endocannabinoid system (ECS) is a central modulator of metabolic physiology, and the ECS is now increasingly recognized as a regulator of adipose tissue ...

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Expression of matrix metalloproteinases and components of the endocannabinoid system in the knee joint are associated with biphasic pain progression in a rat model of osteoarthritis

Expression of matrix metalloproteinases and components of the endocannabinoid system in the knee joint are associated with biphasic pain progression in a rat model of osteoarthritis

... the endocannabinoid system (ECS) is implicated in joint function and modulation of nociceptive ...ECS system were revealed at a later stage of OA ...

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The Role of the Endocannabinoid System in the Gynaecological Malignancy

The Role of the Endocannabinoid System in the Gynaecological Malignancy

... the endocannabinoid system may play a decisive role in the development and progression of gynaecological ...The endocannabinoid system activity is very complex, involving different signalling ...

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Fatty acid modulation of the endocannabinoid system and the effect on food intake and metabolism

Fatty acid modulation of the endocannabinoid system and the effect on food intake and metabolism

... acid, AA, AEA, and 2-AG and decreased DHA and EPA, accompanied by weight gain and adipose tissue inflammation when compared to control fed animals [127]. This effectively demonstrated how changes in the linoleic acid ...

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Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa

Lack of association of genetic variants in genes of the endocannabinoid system with anorexia nervosa

... The endocannabinoid system further interacts with the leptinergic system; obese rodents with disturbed leptin signal transduction (ob/ob and db/db mice as well as fa/fa rats) show elevated levels of ...

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Effects of endocannabinoid system, synthetic and nonsynthetic cannabinoid drugs on traumatic brain injury outcome: a narrative review

Effects of endocannabinoid system, synthetic and nonsynthetic cannabinoid drugs on traumatic brain injury outcome: a narrative review

... The endocannabinoid system (ECS) consists of ligands, such as anandamide and 2-arachidonoyl-glycerol (2-AG), receptors ...this system plays a role in compensatory repair ...

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The multiple functions of the endocannabinoid system: a focus on the regulation of food intake

The multiple functions of the endocannabinoid system: a focus on the regulation of food intake

... the endocannabinoid system, not only in the central nervous system but also in peripheral tissues, points to its involvement in the regulation of appetite, food intake and energy metabolism ...

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Endocannabinoid system as a regulator of tumor cell malignancy – biological pathways and clinical significance

Endocannabinoid system as a regulator of tumor cell malignancy – biological pathways and clinical significance

... The endocannabinoid system (ECS) comprises cannabinoid receptors (CBs), endogenous cannabinoids, and enzymes responsible for their synthesis, transport, and degradation of ...of endocannabinoid and ...

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The Effect of Eight Weeks of Aerobic, Anaerobic and Resistance Training on Some Factor of Endocannabinoid System, Serotonin, Beta-Endorphin and BDNF in Young Men

The Effect of Eight Weeks of Aerobic, Anaerobic and Resistance Training on Some Factor of Endocannabinoid System, Serotonin, Beta-Endorphin and BDNF in Young Men

... some endocannabinoid, serotonin, beta-endorphin and BDNF agents of young ...measure endocannabinoid system, serotonin, beta-endorphin and BDNF ...the endocannabinoid system, it is ...

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Function of the Endocannabinoid System in Neurodegenerative Diseases and Cancers

Function of the Endocannabinoid System in Neurodegenerative Diseases and Cancers

... Alzheimer’s disease (AD) is a chronic neurodegenerative disease that presents in patients as short-term memory loss, aphasia, and apraxia [5] [14]. As AD ad- vances, patients develop judgement and language impairment, ...

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The role of the endocannabinoid system in female reproductive tissues

The role of the endocannabinoid system in female reproductive tissues

... the endocannabinoid system in female reproductive tissues and ...which endocannabinoid signaling can affect ovarian function in both physiological and pathophysiological ...

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The role of the endocannabinoid system in the pathophysiology of mood disorders

The role of the endocannabinoid system in the pathophysiology of mood disorders

... the endocannabinoid system in the neurobiology of mood ...(i.e., endocannabinoid reuptake inhibition or reduced enzymat- ic degradation) stimulation of cannabinoid CB1 receptors exerts an ...

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The in vitro GcMAF effects on endocannabinoid system transcriptionomics, receptor formation, and cell activity of autism-derived macrophages

The in vitro GcMAF effects on endocannabinoid system transcriptionomics, receptor formation, and cell activity of autism-derived macrophages

... and GoTaq Flexi DNA polymerase (Promega, Madison, WI, USA), and amplification reactions using specific primers and conditions for human genes under analysis were carried out. Sequences for the human mRNAs from GeneBank ...

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The effects of obesity, diabetes and metabolic syndrome on the hydrolytic enzymes of the endocannabinoid system in animal and human adipocytes

The effects of obesity, diabetes and metabolic syndrome on the hydrolytic enzymes of the endocannabinoid system in animal and human adipocytes

... was also observed without the diabetic rats. Given that MGL has distinct roles in lipolysis and signalling, the in- creased activity of MGL in our studies may reflect an in- crease in the endocannabinoid ...

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Tapping into the endocannabinoid system to ameliorate acute inflammatory flares and associated pain in mouse knee joints

Tapping into the endocannabinoid system to ameliorate acute inflammatory flares and associated pain in mouse knee joints

... cannabinoid system is a promising target for treating arthritis because of the localization of CB1 re- ceptors on joint primary afferents [17] and CB2 receptors in the synovium ...cannabinoid system can ...

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Acute administration of beta-caryophyllene prevents endocannabinoid system activation during transient common carotid artery occlusion and reperfusion

Acute administration of beta-caryophyllene prevents endocannabinoid system activation during transient common carotid artery occlusion and reperfusion

... cannabinoidergic system that may contribute to regulate cellular functions that depend upon CB1 receptor activa- ...the endocannabinoid and endovanilloid pathways have been found to antagonistically ...

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The endocannabinoid system and its therapeutic exploitation in multiple sclerosis: Clues for other neuroinflammatory diseases.

The endocannabinoid system and its therapeutic exploitation in multiple sclerosis: Clues for other neuroinflammatory diseases.

... practice. All these strategies are subject of intense research. Several clinical trials have been reported or are ongoing with MAGL and FAAH inhibitors (see for a recent review Chicca et al., 2015). For example, the ...

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Gene Expression o Endocannabinoid System Components in Skeletal Muscle and Adipose Tissue of South Asians and White Caucasians with Overweight

Gene Expression o Endocannabinoid System Components in Skeletal Muscle and Adipose Tissue of South Asians and White Caucasians with Overweight

... studies showed that tissue contrast enhancement curves and TKA parameters strongly depend on the injection protocol.. Increased injection duration.[r] ...

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Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion

Involvement of the endocannabinoid system in the physiological response to transient common carotid artery occlusion and reperfusion

... extensive system with relative basic levels of each component that is modulated by different and concurring molecular mechanisms [8, ...eCB system in neuroprotection is somewhat controversial, data on focal ...

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