Endocrine Disruption
Routes and mechanisms of embryonic hormone exposure and endocrine disruption in a viviparous lizard
... metallicus are well known (Stewart and Thompson 1994; Jones and Swain 1996; Stewart 2013). Importantly aromatase activity in placental tissue is high (comparable with that in maternal ovaries), at the time of embryonic ...
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Application of Molecular Biological Biomarkers to Endocrine Disruption Studies
... EDCs may bring about great impact on the ecological environment and human health, and people have begun to understand the importance of studying the potential risks resulted from the pollution of EDCs. It is important to ...
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Effects of multiwalled carbon nanotubes and triclocarban on several eukaryotic cell lines: elucidating cytotoxicity, endocrine disruption, and reactive oxygen species generation
... To date, many studies on the safety of different CNT materials have been conducted but the results are often controversial and depending of the species of the applied CNT. A wide range of results from in vitro studies, ...
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Influence of diet and maternal dioxin on endocrine disruption : puberty, metabolic syndrome, and breast cancer
... This study examined how environmental estrogen exposures, such as obesegenic diet- and maternal TCDD exposure, impact breast cancer. A better understanding of the biological and molecular history of breast cancer among ...
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Endocrine Disruption and Female Pubertal Timing.
... Age of pubertal onset in girls is advancing in western societies (1). This is not only a concern because of the psychological and social burdens which accompany it, but also because it may be an indication of early onset ...
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Evidence of ectoparasite induced endocrine disruption in an imperiled giant salamander, the eastern hellbender (Cryptobranchus alleganiensis)
... Parasitic leeches and trypanosomes release chemical signals into their hosts to evade immuno-detection, but it is unknown whether these compounds manipulate host behavior or endocrine physiology. We determined ...
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An integrated assessment of estrogenic endocrine disruption in the Irish marine envrionment, with particular emphasis on chemical measurements
... polychlorinated biphenyls (PCBs), dioxins and furans, alkylphenol ethoxylates (APEs), phthalates, butylated hydroxyanisole (BHA) and bisphenol A (BPA) and mixtures of estrogen mimicking chemicals were reviewed, using ...
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Association of environmental chemicals & estrogen metabolites in children
... to disruption of endocrine pathways and altered hormonal status in both animal and human ...with endocrine disruption or hormonally derived cancers in vitro and in animal models [7, 23 – ...
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Endocrine Disruptor Compounds (EDC) Effects on Reproduction
... as endocrine disruptor compounds ...to endocrine disruption are described: either by direct interaction with hormone receptors leading to its stimulation or inhibition, or by effect on endogenous ...
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Ameliorative Effects of Sesame Seed Oil Against Penconazole-Induced Testicular Toxicity and Endocrine Disruption in Male Rats
... and endocrine disruption induced by the oral intoxication with penconazole (PENZ), a commonly used systemic triazole fungicide, in adult male Wistar ...the endocrine-disrupting potential and ...
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EFFECT OF DERMAL EXPOSURE OF PREGNANT RATS TO DIAZINON ON THE TESTIS OF MALE OFFSPRING
... the endocrine disruption hypothesis, exposure to chemicals, including pesticides, results in a range of reproductive disturbances in humans and in various wildlife species, some of which may be used as ...
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Search | Preprints
... neurological disorder where there are observable patches of depigmented skin 183, 182 . TSC is characterized by neurological manifestations such as infantile spasms, epilepsy, cognitive disabilities and autism 182 . ...
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Cushing syndrome: uncovering Carney complex due to novel PRKAR1A mutation
... PPNAD can occur as part of CNC, a rare multiple neoplasia syndrome characterized by spotty skin pigmentation, myxomas and endocrine tumors. The diagnosis of CNC can be made based on major clinical manifestations, ...
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Multiple endocrine neoplasia type 1
... Multiple Endocrine Neoplasia type 1 (MEN1) is a rare autosomal dominant hereditary cancer syndrome presented mostly by tumours of the parathyroids, endocrine pancreas and anterior pituitary, and ...
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Multiple endocrine neoplasia type 1 presenting with concurrent insulinoma and prolactinoma in early-adolescence
... In pediatrics, hypoglycemia most commonly presents in infants and toddlers. Presentation in early adolescence is unusual, but can be due to ingestions including hypoglycemic agents or ethanol or hormonal causes, such as ...
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Case Report A case of breast primary neuroendocrine carcinoma treated with neoadjuvant endocrine therapy
... neoadjuvant endocrine therapy was well demonstrated to treat breast primary neuroendocrine carcinoma with hor- mone receptor positive, which provided a good reference for similar ...
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Human endometrial cell coculture reduces the endocrine disruptor toxicity on mouse embryo development
... chemicals and several studies have reported the detri- mental effects PCBs on animal reproduction systems. In human beings, complications such as reduced birth weight, diminished head circumference and reduced ges- ...
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Comparative study of immunocytochemical patterns of somatotrophs, mammotrophs, and mammosomatotrophs in the porcine anterior pituitary
... The anterior pituitary consists of three regions (pars distalis, pars intermedia, and pars tuberalis) within the sella turcica and lies outside blood-brain barrier. It does not belong to nerve terminals and forms of a ...
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Haematological profile of Channastriatus exposed to sublethal concentrations of endocrine disruptor chemical Triclosan
... The results of the present investigation show that the triclosan exposure imposed a drastic reduction in the total count of RBC’s. Triclosan treated fish showed a stastically significant decrease in RBC. The reduction ...
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Frailty and the endocrine system
... Persistently high 206 levels of cortisol have been associated with increased catabolism of skeletal 207 muscle 33, so a link between chronically elevated cortisol and frailty is 208 biol[r] ...
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