Endocrine tumors
Production of GAWK (chromogranin B 420 493) like immunoreactivity by endocrine tumors and its possible diagnostic value
... pheochromocytoma (GAWK [1-17]-LI, 18,173 +/- 3,915; GAWK [20-38]-LI, 17,852 +/- 2,763 [mean +/- SEM] pmol/g wet wt tissue; n = 9), which were at least ten times higher than any other tumors producing GAWK-LI. High ...
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Identification of somatostatin receptor subtypes and an implication for the efficacy of somatostatin analogue SMS 201 995 in treatment of human endocrine tumors
... expression of SSTR subtypes in insulinomas. Interestingly, SSTR3 mRNA, which is highly expressed in rat pancreatic islets, is not expressed in normal human pancreatic islets, while SSTR1, SSTR2, and SSTR4 mRNAs are ...
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Endocrine tumors of the gastrointestinal tract and pancreas:grading, tumor size and proliferation index do not predict malignant behavior
... In endocrine tumors, a number of clinicopathologic criteria proved to be useful predictors of malignant behavior; these include: site of origin; tumor type; tumor size; invasion of nearby tissue or deep ...
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Running Title: Hypothalamic endocrine tumors
... These tumors are composed of large mature ganglion cells that vary in size and shape with abundant cytoplasm containing Nissl substance (Figure 1); they may be binucleated or even ...Some tumors have focal ...
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Loss of heterozygosity suggests multiple genetic alterations in pheochromocytomas and medullary thyroid carcinomas
... in endocrine tumors, we tested 41 pheochromocytomas (34 sporadic and 7 familial) and 11 medullary thyroid cancers (MTC) (10 sporadic and 1 familial) for LOH near a variety of potentially important genetic ...
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Posttransplantation malignancy in a patient presenting with weight loss and changed bowel habits: a case report
... other endocrine tumors, oral cavity cancers, cervix and vaginal cancers, non-Hodgkin lymphoma, renal, ure- teral, and bladder cancer, colorectal cancer, lung cancer, and brain tumors ...brain ...
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Intestinal neuroendocrine tumor in a patient with pituitary adenoma A case report and review of the current screening recommendations
... We believe that screening patients suspected to have any familial type of endocrine tumors for NETs, could help early diagnosis in asymptomatic patients, and offer them the best chance for curative ...
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Multiple endocrine neoplasia type 1 presenting with concurrent insulinoma and prolactinoma in early-adolescence
... of tumors in at least two MEN1 affected organs (most commonly parathyroid, pituitary, ...two tumors at the time of diagnosis has not been previously reported in a ...additional endocrine ...
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Gastrinoma and neurofibromatosis type 2: the first case report and review of the literature
... of endocrine and non endocrine manifestations have been ...neuro- endocrine tumors in NF1 might be the loss of neurofibro- min, a tumor suppressor protein, representing the main product of the ...
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Sinonasal Undifferentiated Carcinoma—A Case Report
... neuro endocrine tumors show a varied histomorphological spectrum ranging from esthesio- neuroblastoma (ENB), sinonasal undifferentiated carcinoma (SNUC), sinonasal neuroendocrine carcinoma, and small cell ...
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Cushing syndrome: uncovering Carney complex due to novel PRKAR1A mutation
... PPNAD can occur as part of CNC, a rare multiple neoplasia syndrome characterized by spotty skin pigmentation, myxomas and endocrine tumors. The diagnosis of CNC can be made based on major clinical ...
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123I-labeled metaiodobenzylguanidine for diagnosis of neuroendocrine tumors
... pheochromocytomas are frequently associated with other endocrine tumors, for example as part of multiple endocrine neoplasia (MEN) type 2. The clinical features of familial pheochromocytomas are ...
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Composite signet-ring cell/neuroendocrine carcinoma of the stomach with a metastatic neuroendocrine carcinoma component: a better prognosis entity
... The histiogenesis of these composite tumors remains unclear. It has recently been proposed that signet-ring cell carcinomas originate from the gradual dedifferentiation from enterochromaffin-like (ECL) cells ...
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Evolving Diagnostic and Treatment Strategies for Pancreatic Neuroendocrine Tumors
... Tumor cell growth, proliferation, and apoptosis are regu- lated in part by a serine-threonine kinase called the mammalian target of rapamycin (mTOR). This enzyme also mediates downstream signaling from a number of ...
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Two Adults with Adrenal Myelolipoma and 21-Hydroxylase Deficiency
... adrenal tumors has been reported in CAH patients and in heterozygote mutation carriers, possibly due to increased levels of ACTH which acts as a growth factor ...adrenal tumors later in life [15, ...
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Perivascular epithelial cell tumor (PEComa) of the pancreas: a case report and review of previous literatures
... the tumors were composed of epithe- lioid tumor cells possessing clear to focally granular eosinophilic cytoplasm, centrally located, round to oval nucleus and inconspicuous nucleoli, diffusely prolifer- ated in ...
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Efficient development and usability testing of decision support interventions for older women with breast cancer
... Patients facing the decision only DESI-S, Primary endocrine therapy/surgery+endocrine therapy DESI; DESI-C, chemotherapy DESI; Bo, booklet; Br, brief decision aid; SUT, Primary endocrine[r] ...
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endocrine activities.pdf
... The endocrine system is responsible for many amazing bodily processes: growth, sexual development, the fight or flight response to danger, and the process by which cells make energy and synthesize ...the ...
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Endocrine Review.pdf
... Blood glucose increases → release of insulin increases → conversion of glucose into glycogen increases → blood glucose decreases.. Blood glucose decreases → release of insulin d[r] ...
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Endocrine emergencies
... many endocrine emergencies occur in patients with underlying endocrine pathology, it is important not to miss the diagnosis in de novo ...appropriate endocrine hormones have been shown to decrease ...
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