Endogenous Retroviruses
Endogenous Retroviruses: Thierry Heidmann wins the 2009 Retrovirologyprize
... IAP endogenous retroviruses to the male germline, using lacZ-marked ele- ments introduced by transgenesis, the involvement of CpG-methylation in somatic restriction, and the evidence for somatic ...
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Evolution and Distribution of Class II-Related Endogenous Retroviruses
... exogenous retroviruses into seven genera (alpha-, beta-, gamma-, delta-, and epsilonretro- viruses; lentivirus; and spumavirus) (12, 26, 34, ...exogenous retroviruses (19, 20, ...related endogenous ...
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Distribution, Diversity, and Evolution of Endogenous Retroviruses in Perissodactyl Genomes
... ABSTRACT The evolution of mammalian genomes has been shaped by interactions with endogenous retroviruses (ERVs). In this study, we investigated the distribution and diversity of ERVs in the mammalian order ...
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Infectious Endogenous Retroviruses in Cats and Emergence of Recombinant Viruses
... or endogenous accord- ing to their mode of transmission. Endogenous retroviruses (ERVs) are present in all vertebrate genomes and are thought to be the remnants of ancestral germ line infections by ...
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Rate of Recombinational Deletion among Human Endogenous Retroviruses
... Endogenous retroviruses (ERVs) are the proviral form of exogenous viruses that have integrated into germ line cells and are passed vertically from parent to offspring ...
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Unique Spectrum of Activity of Prosimian TRIM5α against Exogenous and Endogenous Retroviruses
... an endogenous lentivirus in ...as endogenous retroviruses until the discovery of rabbit endogenous lentivirus type K (RELIK) in lagomorphs and PSIV in lemurs, pushing back the estimated origin ...
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Endogenous retroviruses and multiple sclerosis–new pieces to the puzzle
... Human endogenous retroviruses (HERVs) are rem- nants of prehistoric exogenous retroviruses, integrated in the human genome during primate evolution through germ line ...
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Expression Profiles of Endogenous Retroviruses in Old World Monkeys
... Human endogenous retroviruses (HERVs) comprise at least 8 to 9% of the human genome. They are associated with both critical biological function such as placental for- mation (6, 28) and with diseases such ...
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Human endogenous retroviruses: Their possible role in the molecular etiology of the schizophrenia
... Human endogenous retroviruses (HERVs) represent footprints of previous retroviral infections. They are integrated within the human germ line and constitute approximately 8% of our genome. They have the po- ...
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Variable Transcriptional Activity of Endogenous Retroviruses in Human Breast Cancer
... Human endogenous retroviruses (HERVs) account for up to 9% of the human genome and include more than 800 elements related to betaretroviruses. While mouse mammary tumor virus (MMTV) is the accepted ...
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Evolutionary Spread and Recombination of Porcine Endogenous Retroviruses in the Suiformes
... porcine endogenous retroviruses (PERV) in general (pol gene), while the distribution of long terminal repeat (LTR) types (with or without repeats in U3) and env genes (classes A, B, and C) were determined ...
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The identification and classification of endogenous retroviruses in the horse genome
... Endogenous retroviruses (ervs) are sequences that derived from ancient retroviral infections of germ cells and integrated in humans, mammals and other vertebrates millions years ...equine endogenous ...
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Determinants of High Titer in Recombinant Porcine Endogenous Retroviruses
... Porcine endogenous retroviruses (PERVs) pose a potential stumbling block for therapeutic xenotransplan- tation, with the greatest threat coming from viruses generated by recombination between members of the ...
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Mobilization of Endogenous Retroviruses in Mice after Infection with an Exogenous Retrovirus
... of endogenous retroviruses in the genomes of vertebrate species, including mice and humans, has been known for many years, it was not until the sequencing of the human and mouse genomes that the extent to ...
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Characterizing and Mapping Porcine Endogenous Retroviruses in Westran Pigs
... Porcine endogenous retroviruses (PERVs) are proviruses, inherited in a stable Mendelian fashion (31), although they can also be acquired through infection. Type C virus particles re- leased in two cell ...
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Genome-Wide Detection and Characterization of Endogenous Retroviruses in Bos taurus
... Endogenous retroviruses (ERVs) are the proviral phase of exogenous retroviruses that become integrated into a host germ line. They can play an important role in the host genome. Bioinformatic tools ...
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Role of DNA Methylation in Expression and Transmission of Porcine Endogenous Retroviruses
... Porcine endogenous retroviruses (PERV) represent a major safety concern in pig-to-human xenotransplantation. To date, no PERV infection of a xenograft recipient has been recorded; however, PERVs are ...
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Mapping Full-Length Porcine Endogenous Retroviruses in a Large White Pig
... Xenotransplantation may bridge the widening gap between the shortage of donor organs and the increasing number of patients waiting for transplantation. However, a major safety issue is the potential cross-species ...
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Unexpected Diversity and Expression of Avian Endogenous Retroviruses
... ABSTRACT Endogenous retroviruses (ERVs) were identified and characterized in three avian genomes to gain insight into early retroviral ...that endogenous alpharetroviruses were present in chicken ...
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Endogenous retroviruses in the human genome sequence
... protein (Figure 1b). Analysis of the draft human genome has so far found only three HERV proviruses with complete open reading frames for gag, pol and env (the three essential viral genes) [1], and at least one of these ...
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