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Endometrial Cancer (EC)

SOX17 is a tumor suppressor in endometrial cancer

SOX17 is a tumor suppressor in endometrial cancer

... Endometrial cancer (EC) is the most common gynecologic malignancy, with an estimated 47,130 new cases and 8,010 deaths occurring in 2014 [1]. Two clinicopathological variants are distinguished: estrogen- ...

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Controversies in the management of endometrial cancer 2012

Controversies in the management of endometrial cancer 2012

... of endometrial cancer, Grade 3 endometrioid cancer, papillary serous cancer, clear cell cancer, undifferentiated, and squamous histologies have a poorer prognosis and may merit com- ...

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Review Article Endometrial regenerative cells and endometrial cancer stem cells: new insights may provide novel therapeutic targets

Review Article Endometrial regenerative cells and endometrial cancer stem cells: new insights may provide novel therapeutic targets

... to cancer stem cells in EC [49, ...in cancer has been accepted as an indicator of unfavorable ...normal endometrial stem cells ...identify endometrial cancer stem cells ...

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RAB8A a new biomarker for endometrial cancer?

RAB8A a new biomarker for endometrial cancer?

... Endometrial cancer (EC) is a common gynecological ma- lignancy and the incidence is gradually increasing due to life patterns [1]. Current methods of diagnosis of EC rely on invasive techniques, such as ...

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Surgical Treatment of Endometrial Cancer

Surgical Treatment of Endometrial Cancer

... year endometrial cancer is diagnosed in approximately ...with endometrial cancer will also ...in endometrial cancer patients stage I and II should be replaced by laparoscopic ...

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Original Article Elevated expression of RIT1 correlates with poor prognosis in endometrial cancer

Original Article Elevated expression of RIT1 correlates with poor prognosis in endometrial cancer

... in endometrial cancer cell lines and endometrial cancer tissues at mRNA and protein ...in endometrial carcinomas ...of endometrial cancer and might serve as a target for ...

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Original Article Role of endometrial cancer abnormal MMR protein in screening Lynch-syndrome families

Original Article Role of endometrial cancer abnormal MMR protein in screening Lynch-syndrome families

... colon cancer (HNPCC), is an autosomal dominant syndrome that predispos- es patients to multiple malignancies including colorectal cancer (CRC), endometrial cancer (EC), and ovarian ...colon ...

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Endometrial cancer with cervical extension in an obese patient: options for surgery versus combined chemoradiotherapy and extra-fascial hysterectomy

Endometrial cancer with cervical extension in an obese patient: options for surgery versus combined chemoradiotherapy and extra-fascial hysterectomy

... hysterectomy in the setting of cervical cancer. In that trial, the inves- tigators found that the rate of disease-free survival at 4.5 years was 86.0% with minimally invasive surgery and 96.5% with open surgery, ...

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USP14 is a predictor of recurrence in endometrial cancer and a molecular target for endometrial cancer treatment

USP14 is a predictor of recurrence in endometrial cancer and a molecular target for endometrial cancer treatment

... with endometrial adenocarcinoma into two groups, Type I or Type II ...I endometrial adenocarcinomas, the most common subtype, typically occur in the setting of excessive estrogen and consist of low grade ...

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Identification of nine new susceptibility loci for endometrial cancer.

Identification of nine new susceptibility loci for endometrial cancer.

... OncoArray endometrial cancer analysis were supported by NHMRC project grants (ID#1031333 and ID#1109286) to ...by Cancer Research UK and the Oxford Comprehensive Biomedical Research ...(COGS), ...

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Evaluating the p FOXO1/FOXO1 Ratio: An Alternative Strategy for Endometrial Cancer Diagnosis

Evaluating the p FOXO1/FOXO1 Ratio: An Alternative Strategy for Endometrial Cancer Diagnosis

... gastric cancer cells correlates with microvessel area and the expressions of angiogenesis-related mole- ...dometrial cancer cells and is involved in normal growth control and maintenance of genomic ...human ...

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The prevalence of Lynch syndrome in women with endometrial cancer: a systematic review protocol

The prevalence of Lynch syndrome in women with endometrial cancer: a systematic review protocol

... This systematic review looks to collate data from indi- vidual studies in order to determine robust estimates of the prevalence of Lynch syndrome in women with endo- metrial cancer. The information provided by ...

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Endometrial cancer—how many patients could benefit from sentinel lymph node dissection?

Endometrial cancer—how many patients could benefit from sentinel lymph node dissection?

... Endometrial cancer is the most common carcinoma of the female genital tract with over 300,000 new cases di- agnosed each year worldwide ...in endometrial cancer, ...

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Potential new biomarkers for endometrial cancer

Potential new biomarkers for endometrial cancer

... We evaluated overall patient survival in patients with the highest 20% of biomarker expression and patients with the lowest 20% biomarker expression to determine whether the elevation of these genes had any impact on ...

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Nucleophosmin/B23 is a negative regulator of estrogen receptor a expression via AP2g in endometrial cancer cells

Nucleophosmin/B23 is a negative regulator of estrogen receptor a expression via AP2g in endometrial cancer cells

... including endometrial [27], ovarian [28], thyroid [29], gastric [30], colon [31], prostate [32], and bladder [33, 34] ...of endometrial cancer ...estrogen-dependent endometrial tumorigenesis, ...

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Endometrial cancer following endometrial resection

Endometrial cancer following endometrial resection

... of endometrial cancer share the same risk ...that endometrial polyps are characterized by aberrations of specific chromosome regions that probably involve genes related to the prolifer- ative process ...

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A successful intraoperative diagnosis of coexisting lymphoma and endometrial cancer

A successful intraoperative diagnosis of coexisting lymphoma and endometrial cancer

... with endometrial cancer (Table 1) ...for endometrial cancer, and its diagnosis has been made only incidentally, after staging ...an endometrial cancer is so rare, it may be ...

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Oral contraception and risk of endometrial cancer

Oral contraception and risk of endometrial cancer

... for endometrial remodeling, and histological changes during use of COC, are highly suggestive of a protective effect of the proge- stagen component against estrogen-related (type 1) endo- metrial ...of ...

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Progesterone potentiates the growth inhibitory effects of calcitriol in endometrial cancer via suppression of CYP24A1

Progesterone potentiates the growth inhibitory effects of calcitriol in endometrial cancer via suppression of CYP24A1

... in cancer cell lines [13, 14, 22, 26]. In endometrial cancer cells, CYP24A1 RNA splicing is rapid and efficient, and can be regulated by calcitriol ...in cancer cells pretreated with ...

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Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGF-β signaling pathway

Nestin suppression attenuates invasive potential of endometrial cancer cells by downregulating TGF-β signaling pathway

... pancreatic cancer increased cell motility and cause phenotypic changes associated with the epithelial-mesenchymal transition ...prostate cancer cells [32, 33] and suppresses proliferation of nasopharyngeal ...

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