Endothelial barrier function
Lipopolysaccharide (LPS) binding protein and soluble CD14 function as accessory molecules for LPS induced changes in endothelial barrier function, in vitro
... Bacterial LPS induces endothelial cell (EC) injury both in vivo and in vitro. We studied the effect of Escherichia coli 0111:B4 LPS on movement of 14C-BSA across bovine pulmonary artery EC monolayers. In the ...
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Synergism of MSC-secreted HGF and VEGF in stabilising endothelial barrier function upon lipopolysaccharide stimulation via the Rac1 pathway
... stabilise endothelial barrier function in acute lung injury via paracrine hepatocyte growth factor ...Vascular endothelial growth factor (VEGF), which is secreted by MSCs, is another key ...
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Original Article Schistosoma japonicum serine protease inhibitor increases endothelial barrier function
... the endothelial barrier function may become compromised with severe ...the barrier is enhanced it may limit further metabolic waste penetration, even bacterial or viral ...the ...
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Mesenchymal stem cells microvesicles stabilize endothelial barrier function partly mediated by hepatocyte growth factor (HGF)
... from endothelial cells using RIPA lysis buffer supplemented with 1 mmol/L phenylmethanesulfonyl fluoride (PMSF, Beyotime Institute of Biotechnology, Shanghai, China), separated by 6% or 12% SDS-PAGE and ...
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HIF2α signaling inhibits adherens junctional disruption in acute lung injury
... regulate endothelial permeability and angiogenesis by antagonizing each other (25, 30, 35, ...and function of tumor vessels through TIE2 activation ...lial barrier function in sepsis (37), it ...
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Endothelial cell–restricted disruption of FoxM1 impairs endothelial repair following LPS induced vascular injury
... of endothelial integrity after vascular injury is vital for endothelial barrier function and vascular ...of endothelial barrier repair follow- ing ...of endothelial ...
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Chronic ingestion of alcohol modulates expression of ubiquitin editing enzyme A20 in lung macrophages
... the endothelial barrier function of the lung was compromised, showing excessive infiltration of Evans blue in the lung indi- cating lung ...lung endothelial barrier ...the ...
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Leukadherin-1 ameliorates endothelial barrier damage mediated by neutrophils from critically ill patients
... cellular function need only include a subpopulation of receptors held in the activated ...to endothelial ICAM and tether blood neutrophils to the vasculature such that tissue emigration does not en- ...
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Stickel, Diana (2017): Cytosolic and mitochondrial Ca2+ handling in pulmonary arterial smooth muscle and endothelial cells. Dissertation, LMU München: Medizinische Fakultät
... the barrier can be quantified in a transwell permeability assay or the resistance of a small alternating current which is applied to the endothelial layer can be analyzed using the Electrical Cell-Substrate ...
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RSPO3 impairs barrier function of human vascular endothelial monolayers and synergizes with pro-inflammatory IL-1
... and endothelial barrier function (Lim et ...vascular endothelial cells (accession GSE62281, NCBI GEO data repository) (Skaria et ...vascular endothelial barrier function ...
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Effects of Ebola Virus Glycoproteins on Endothelial Cell Activation and Barrier Function
... that endothelial cell function was im- paired during ...on endothelial cell activation and barrier function, we used immunofluorescence analyses and RT-PCR as well as impedance ...
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Effect of amplitude and duration of impulsive pressure on endothelial permeability in in vitro fluid percussion trauma
... regulate endothelial barrier ...a barrier-disruptive chemical agonist, al- though a pathological cyclic stretch enhances the decrease ...in endothelial monolayers from a mouse brain ...
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Neutrophils from critically ill septic patients mediate profound loss of endothelial barrier integrity
... of endothelial barrier dysfunc- ...of endothelial permeability to neutrophils is beneficial to the host, allowing for bacterial containment and eradication; however, its prolonged and dysregulated ...
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A Vascular Permeability Assay Using an In Vitro Human Microvessel Model Mimicking the Inflammatory Condition
... the endothelial barrier function (A) Left: timelines of the treatments applied to microvessels; right: representative images of the responses to the treatments (images taken at 90 min, scale bars: ...
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An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons
... elevated barrier tightness in conjunction with primary brain pericytes and neural progenitor-derived astrocytes and neurons, approaching in vivo TEER meas- urements ...BBB function in human health and ...
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Immortalized Human Brain Endothelial Cell Line HCMEC/D3 as a Model of the Blood-Brain Barrier Facilitates In Vitro Studies of Central Nervous System Infection by Cryptococcus neoformans
... brain endothelial cells in- fected with ...cell barrier, consistent with a trans- cellular movement of ...the endothelial cells ...dothelial barrier, suggesting that these cryptococcal cells ...
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Adenosine receptor signaling: a key to opening the blood–brain door
... AR engagement on the choroid plexus epithelial cell line CPLacZ-2 by CGS21680 induced CX3CL1 expression and promoted lymphocyte transmigration suggesting that CX3CL1 induction by extracellular adenosine con- tributes to ...
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Comparison of apoptosis in human primary pulmonary endothelial cells and a brain microvascular endothelial cell line co cultured with Plasmodium falciparum field isolates
... pRBC-triggered EC apoptosis in the brain, lungs and kidneys has been observed in patients with fatal malaria [12, 13]. Using cocultured human lung EC (HLEC) and pRBC field isolates from Gabon, we showed that al- though ...
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On the relationship of interior point methods
... In this paper, we show that the moving directions of the primal-affine scaling method with logarithmic barrier function, the dual-affine scaling method with logarithmic barrier function,[r] ...
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Prostaglandin D 2strengthens human endothelial
... barrier disruption in primary human pulmonary and dermal microvascular endothelial cells as well 85.. as in pulmonary artery endothelial cells by activating EP4 and only to a small exte[r] ...
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